Adults and the elderly are quite often concerned about heart disease, one of which is ischemia. It is not uncommon for people to experience shortness of breath, dizziness, or tinnitus. To help get rid of unpleasant symptoms and cope with the disease can means "Triductan".
The drug "Triductan" instructions for use defines it as an anti-ischemic and antihypoxic drug. It is used for cardiological, ophthalmic, and otolaryngological diseases.
Composition and release form
"Triductan" and "Triductan MB" are produced in the form of coated tablets. The main active ingredient is trimetazidine dihydrochloride. The composition of the tablets "Triductan" includes 20 mg of the active substance. The medicine "Triductan MV" includes 35 mg of the active substance. As you can see, the active ingredient is the same, so the properties, indications, contraindications and side effects of the drugs are the same.
"Triductan MB" (35 mg) also consists of excipients. They aremicrocrystalline cellulose, mannitol, glycol montan wax, magnesium stearate, and type B methacrylate ammonium copolymer. The drug at a dosage of 20 mg also has excipients such as corn starch, polyvinylpyrrolidone, mannitol, talc, magnesium stearate. The medicine with a dosage of 20 mg has two numbers - 30 and 60. These numbers show the number of tablets that are in the carton. The drug number 30 includes 3 blisters with tablets, each blister contains 10 tablets. The drug with a dosage of 35 mg belongs to number 60. "Triductan MV" No. 60 is available in a carton box containing 6 blisters of 10 tablets.
Pharmacological properties
The main constituent trimetazidine has an effect on cellular metabolism, thereby preventing the level of ATP from decreasing under the condition of hypoxia. The drug normalizes the energy balance in cells and, by regulating the function of ion channels in cell membranes, maintains cellular homeostasis. Thanks to this drug, the process of glucose oxidation is stimulated, and the process of fatty acid oxidation is suspended. Due to this, the energy metabolism of the heart muscle is supported. "Triductan" helps to prevent the development of intracellular acidosis. Trimetazidine reduces infiltration and migration of reperfused and ischemic cardiac muscles. In addition, "Triductan" increases the coronary reserve, reduces angina attacks. Thanks to the drug, the need for nitrates for patients withischemia.
Indications for use
"Triductan" is used in cardiology for long-term therapy of coronary disease, as well as for the prevention of angina attacks in combination with other drugs. Also, the drug is used in ophthalmology for chorioretinal disorders of ischemic origin. In addition, the drug can be used in the treatment of vestibular disorders also of ischemic origin, such as hearing loss, dizziness or tinnitus.
Contraindications
The drug is contraindicated in case of hypersensitivity to any components of the drug. You can not take "Triductan" and people who suffer from severe violations of the liver and kidneys. During pregnancy and lactation, the drug should not be taken. It is undesirable to use it in children under 18 years of age, since there is no data on the safety of this drug at this age.
Adverse reactions
Despite the fact that patients usually tolerate treatment with Triductan well, the instructions for use warn of possible adverse reactions. From the side of the nervous system, side effects such as dizziness or headache may appear. Also, muscle hypertonicity and akinesia, various movement disorders, such as unsteady gait, are not excluded. In addition, sleep disturbance is possible. It can be both drowsiness and, conversely, insomnia.
Cardinal and vascular disorders are also possible. To theminclude tachycardia, extrasystoles, palpitations, orthostatic and arterial hypotension, which can be manifested by facial flushing and general malaise.
Gastrointestinal pain may occur as well as nausea, vomiting, constipation or diarrhea. There are also various skin reactions, such as itching, rash, swelling or hives. Common disorders include asthenia and angioedema.
Overdose
The therapeutic range is quite large, this gives a low probability of intoxication of the body with the drug "Triductan". Instructions for use highlights some of the symptoms of an overdose of this medication. These include redness of the face, arterial hypotension, as well as increased side effects. In case of overdose, symptomatic treatment is necessary.
Usage and dosage
This drug is taken orally with food. Take "Triductan" should be one tablet three times a day, "Triductan MV" - one tablet twice a day, preferably in the morning and at night. Take the tablets with plenty of water. This medicine has been used for quite a long time. The course of treatment is determined by the doctor individually for each patient, depending on how the disease proceeds. The treatment regimen can be adjusted if necessary after a couple of months.
It should be taken into account the fact that "Triductan" must be taken as a course, and not just to suppress angina attacks. Attreatment of elderly patients, the dosage regimen does not need to be changed.
Patients who have moderate impaired renal function should take the drug 2 times a day, 1 tablet (20 mg). Elderly people should also take the drug 2 times a day.
Special Instructions
It should be borne in mind that Triductan is not taken to suppress angina attacks. The instructions for use also warn that this drug is not prescribed as primary therapy for myocardial infarction or unstable angina. If unstable angina attacks occur during treatment, the course of the disease should be reviewed and treatment adjusted.
The drug should be discontinued if there is a movement disorder, such as unsteady gait, tremor. After discontinuation of the drug, the symptoms should disappear within a maximum of 4 months. If symptoms persist, you should visit a neurologist.
The drug "Triductan" does not affect hemodynamics. But side effects such as dizziness and drowsiness can affect driving or operating machinery. Therefore, taking this drug is not recommended in this case.
Drug Interactions
Data on interactions with other drugs are as follows. Trimetazidine can be administered in parallel with drugs such as heparin, acetylsalicylic acid, calciparin, beta-blockers, lipid-lowering drugs.drugs, calcium antagonist and also with digitalis preparations. Please note that trimetazidine has no effect on plasma levels of digoxin.
Drug storage
The drug must be kept out of the reach of the child. Storage temperature should not exceed 25 degrees. The medicine must be kept in its original packaging for the duration of the expiration date, which is 24 months.
"Triductan": price and dispensing in a pharmacy
The price of the drug "Triductan" depends on several factors, primarily on the manufacturer and transportation. In pharmacies, the cost ranges from 300 to 400 rubles. In pharmacies, you can also buy Triductan MV. Its price is twice as high - about 600 rubles. The cost of the drug is considered average, but you should not try to buy it without consulting a doctor, as you can harm your he alth and waste money, albeit small.
Analogues of the drug
An analogue of this medicine may be needed if it is not available at the pharmacy, and also if the price does not suit you. Pharmacists most often offer several analogues of the drug "Triductan", the price of which, however, can be either lower or higher than this remedy. The main substitutes are Trimetazid, Rimecor, Preductal MV, Metazidin, Tricard.
Reviews about the drug
Most of the reviews about this drug are positive, but there are very few of them, so it's hard to judge whether the drug is good or not. Patients who have experienced ischemia are grateful to the drug for recovery. People with tinnitus anddizziness, when taking "Triductan" they felt an improvement. But there are also negative reviews. A small percentage of people claim that the drug is completely useless and does not improve he alth. Also, reviews of some people report that the improvement came after two weeks of treatment. The instruction indicates that the drug should be used for a long time, so you should not expect any changes on the next day of taking Triductan. Feedback from athletes is completely different. They claim that a tablet taken before a workout improves physical condition, even with high loads, shortness of breath does not appear. This suggests that the drug still has an effect from the first dose. We can conclude that the reviews about the drug are quite contradictory, so it is better to take it with caution.
It should be remembered that one way or another, this drug affects the heart and, if the dosage is incorrect, can harm the body, so be sure to read the instructions and consult a doctor before use.
