"Grippferon" is an effective and safe drug used for the prevention and treatment of acute colds and viral infections, as well as influenza. Due to this, it is approved for the treatment of such pathologies in infants and pregnant women.
"Grippferon" is an immunomodulatory, antiviral and anti-inflammatory agent for intranasal use.
Description
The main active ingredient of the medical product is a highly active recombinant, that is, produced by genetic engineering, interferon a-2. The drug is absolutely safe with respect to virus contamination, which is extremely important, since hepatitis B, C, D, as well as such dangerous pathologies as HIV, CMV and other blood-borne infections are widespread in the modern world.
The medicine is a clear or light yellow liquid with a shelf life of two years. Opened plastic vials should be stored in the refrigeratortemperature up to 8 degrees for no more than one month. Instructions for "Grippferon" are presented below.
Pharmacological action
The mechanism of action of the main substance contained in this medicinal product is based on the elimination of the reproduction of any type of virus that enters the body in any way, including as a result of respiratory activity.
Already on the second day of using this medicine, patients experience a significant reduction in the amount of viruses excreted by breathing, and therefore the risk of infection of people who have come into contact with it.
Unlike other drugs of this group, it prevents the spread of viruses in the nasopharyngeal mucosa, that is, where they first enter with SARS.
This medical product has no direct analogues and surpasses other medicines in terms of universality of action on acute respiratory infections:
- Blocks the mechanisms of reproduction of all known types of respiratory viruses that infect humans.
- High therapeutic efficacy.
- Effective as a drug for emergency prevention.
- Not addictive.
The viruses known at the present stage of medical science are not able to acquire resistance to the action of the main substance of the drug "Grippferon", which is non-toxic and safe. It has been established that the drug reduces the frequency of complications in acute respiratory infections by 50-60% and the number of patients taken by approximately 60-70%medicines.
It has absolutely no contraindications, and is compatible with any other drugs, including a variety of antiviral drugs. "Grippferon" can be used in conjunction with vaccination. This medical device significantly reduces the amount of viruses that are released from the respiratory tract of patients with acute respiratory viral infections (similar to a bandage), and significantly reduces infectivity. It also has very pronounced anti-epidemic properties.
Form and composition
Grippferon release form is indicated in the instructions. The drug is available in the form of a dosed nasal spray and drops of light yellow or colorless color. They are packaged in plastic bottles of 5 or 10 ml.
And what is the composition of the drug "Grippferon"? One dose of spray contains interferon alfa-2b - at least 500 IU. The auxiliary components are sodium chloride, purified water, povidone, sodium hydrogen phosphate dodecahydrate, macrogol, disodium edetate dihydrate, potassium dihydrogen phosphate.
1 ml of drops contains human recombinant interferon alfa-2b at least 10,000 IU, as well as excipients similar to those in the spray.
Viruses against which the drug is active
To date, science knows more than two thousand serotypes of the influenza virus and more than two hundred varieties of other viruses that cause SARS, each of which can also have hundreds of its subspecies.
During influenza epidemics, this particular diseaseOnly 20% of all infected people are ill. The rest of the people suffer, as a rule, from other respiratory pathological conditions, against which vaccination and numerous medical preparations do not protect. The drug "Grippferon" can affect not only the influenza virus, but also other infections that cause respiratory diseases.
In the course of scientific experimental studies, a pronounced antiviral effect of the drug "Grippferon" on the following types of infections was established:
- All existing influenza strains, even H1N1.
- Adenovirus AdV 6.
- Human coronavirus HCoV/SPb/01/03 (229E) - one of the types of this virus causes SARS.
- Respiratory syncytial virus.
- Rubella virus.
- Edmonston measles vaccine strain.
- Vaccinal mumps virus strain L-3.
- Avian flu.
- Parainfluenza virus, strain PG2/SPb5/11/03.
- Lethal strains of bird flu.
Indications
According to the instructions, it is advisable to use Grippferon at the first symptoms of an acute viral disease, the sooner the better. This medication is used in the following cases:
- Prevention and treatment of respiratory infections - influenza, rotavirus, colds.
- For the prevention of such diseases.
What is the difference between "Grippferon" for children and adults?
Medication can beuse in the treatment of newborns, its use is possible during pregnancy, also for people who, due to weakened immunity, are prone to frequent colds, after contact with people who are already ill with SARS and influenza, after hypothermia, etc.
The good efficacy of children's "Grippferon" was established when using this medicine in preschool institutions. Also among people who are subject to so-called risk factors. These are he alth workers, teachers, educators, etc. Indications for the use of "Grippferon" are described in the instructions.
Effectively this medicine is also in the emergency prevention of viral diseases. Unlike vaccines that create long-term resistance to certain subspecies of the influenza virus, the drug is used directly in cases where there is a real threat of a respiratory infection after close contact with patients, as well as for colds, etc.
A single dose of a medication for individual urgent prevention significantly reduces the risk of the onset and development of the disease. In our country, the drug is included in the list of state reserve drugs in case of bird flu epidemics.
Use and dosage
As the instructions for "Grippferon" indicate, when the first manifestations of a respiratory disease occur, this remedy should be dripped into the nose. The dosages used are as follows:
- 1 drop five times a dayday - for children up to a year.
- 2 drops three times a day - for children from one to three.
- 2 drops four times a day - from the age of three to 14 years.
- 3 drops every four hours - for adults.
For prophylactic purposes, the drug is used according to age dosages 2 times a day immediately after contact with the patient. Preventive therapy lasts several days and can be repeated if necessary.
After instillation, the nose should be massaged with a slight movement of the fingers for several minutes. This is done so that the medicine is evenly distributed on the nasal mucosa.
When using the drug "Grippferon" there is no need to apply simultaneously vasoconstrictive therapy, since it relieves swelling of the mucous membrane and facilitates breathing.
Analogues
"Grippferon" has several analogues, which are medicines based on interferons. These medications include:
- Alfaron.
- Interferon.
- "Viferon".
- Kipferon.
- "Cycloferon".
The rest of the drugs that are currently on the pharmacological market are not similar in composition to medicines, however, they are analogues of Grippferon in the antiviral direction of action. These include:
- Ingavirin.
- Citovir.
- "Amixin".
- Peramivir.
- Ingavirin.
- Rebetol.
- Lavomax.
- Kagocel.
- Tamiflu.
- Ribavirin.
- Arbidol.
- Remantadine.
- Relenza.
Special Instructions
In accordance with the instructions for "Grippferon", treatment upon detection of the first signs of the disease leads to a significant weakening of them. This applies to runny nose, cough, headache, fever, mucosal congestion, etc.
The duration of pathological conditions is reduced by 50%. This drug in uncomplicated cases, as a rule, does not require additional symptomatic therapy with aspirin, sulfonamides, vasoconstrictor nasal drops. With an increase in temperature, the drug "Grippferon" can be combined with various antipyretic drugs.
The use of this medication several times reduces the risk of developing complications such as acute bronchitis, sinusitis, pneumonia, etc. The use of the drug for prophylactic purposes, during epidemics in children's and medical teams, reduces the risk of morbidity by almost three times. This is especially true for pregnant women. There are a lot of reviews about Grippferon.
Reviews
The opinion of consumers about this medication is extremely positive. People who used it for the treatment and prevention of acute respiratory viral infections note that the remedy effectively helps with the first symptoms of such diseases, and it can be used during pregnancy and lactation, which is also a big plus that distinguishes this medication from many others.
