Cold always creeps up at the wrong time, but as soon as its signs appear, you need to urgently take measures so as not to get sick even more. Coldact (reviews speak of its effectiveness) always comes to the rescue one of the first. It will relieve chills, pain, eliminate runny nose, swelling and minimize all symptoms of the disease.
Composition, issue, form
"Koldakt" refers to the combined synthetic prolonged medicines. Contains active ingredients such as:
- phenylpropanolamine hydrochloride;
- chlorpheniramine maleate;
- paracetamol.
"Koldakt Flu plus", reviews of which are mostly positive, has different forms of release. It is sold in the form of capsules, tablets, syrup and powder. Each type of drug requires a certain dosage, its intake must be prescribed and monitored by a doctor.
So, the capsule is enclosed in an aluminum blister and contains 8 mg of chlorphenamine maleate, 25 mg of phenylephrine hydrochlorideand 200 mg of paracetamol. It contains not only active ingredients, but also auxiliary components. The latter include: talc, ethylcellulose, hypromellose, diethyl phthalate, dyes, povidone, purified water, sodium disulfite, sucrose, starchy ingredients.
Capsule shell contains gelatin, water, methyl parahydroxybenzoate, propyl parahydroxybenzoate, dyes.
Capsules look like gelatin pills, divided into red and transparent parts, containing white, yellow, orange and red pellets. They are aimed at a long period of action, since the microgranules, getting into the gastrointestinal tract, dissolve gradually in it. This process extends the effectiveness of the drug to twenty-four hours. In total, the aluminum blister contains ten pills, and the intake of the drug is designed for 5-10 days.
Suspension acts, unlike capsules, much faster, but not designed for long-term effects. Its action lasts for four hours. The content of active ingredients in the suspension is much lower than in capsules, therefore, the drug should be taken more often, namely 3-4 times a day. A bottle of 60 ml is enough for two days.
Coldact powder and tablets are cheaper than capsules but not as effective. The number of tablets to be taken per day in case of illness reaches twelve pieces, which is not very convenient and not very useful for the stomach and intestines. The powder is used to treat colds in children who refuse to take pills. He is bred in anydrink, be it milk, juice, water, and so on.
Koldakt: pharmacological action
The drug "Koldakt", reviews of which evaluate it as an effective antipyretic, vasoconstrictor and antiallergic agent, exhibits such properties due to the presence in the composition of substances such as paracetamol, chlorphenamine maleate, phenylephrine hydrochloride. Designed to eliminate the relief of symptoms of acute respiratory infections and colds.
Paracetamol is an anti-inflammatory drug. It is used mainly for acute respiratory viral infections, namely for inflammation of the mucous membranes of the sinuses, larynx, bronchi and similar phenomena. Relieves pain, inflammation, swelling, redness, reduces fever.
Chlorphenamine has an anti-allergic effect, removes tearing, itching, pain in the eye and nasal sinuses. Phenylephrine constricts blood vessels, reduces and removes edema, reduces congestion of the upper respiratory tract and nose.
Indications and contraindications for the use of the drug
"Coldact Flu Plus", reviews of which are simply wonderful in terms of eliminating and treating the symptoms of a cold, is indispensable during the flu, SARS, acute respiratory infections. They also take it for pain and fever manifestations, rhinorrhea.
Contraindications to the use of the drug "Koldakt" (reviews and instructions for use - confirmation of this) are several factors:
- sensitivity to ingredients included incomposition of the drug;
- allergy to drug ingredients;
- atherosclerosis of the coronary arteries;
- high blood pressure;
- diabetes mellitus of any type;
- excess thyroid hormones;
- glaucoma;
- serious complex diseases of internal organs, namely the liver, kidneys, cardiovascular system, bladder, duodenum;
- ulcer;
- blood diseases;
- Children under twelve;
- lack of glucose-6-phosphate dehydrogenase.
Caution should be taken with "Coldact Flu Plus", reviews of the tolerability of which are mostly positive, with hyperbilirubinemia, bronchial asthma, obstruction of the pulmonary tract. In people with a lack of glutathione, the use of the drug can cause serious liver damage.
It is worth refraining from using the drug during pregnancy and while breastfeeding.
Instructions for use
As noted by the instructions for use attached to the Coldact Plus preparation, the capsules have a long-lasting effect. They are taken with plenty of water. For adults and children over 12 years of age, the drug is prescribed one pill every twelve hours, the course of treatment lasts up to 3-5 days.
Suspension should be shaken immediately before use. Assign adults and children over the age of twelve, two teaspoons (or 10 ml) 3-4 times a day,for children in the age group from 6 to 12 years, it is advisable to give the medicine one teaspoon (or 5 ml) 3-4 times a day.
As an antipyretic "Koldakt" (reviews about it confirm its effectiveness in the treatment of colds), it is recommended to take no more than three days. If after this time the drug has not helped, you should consult a doctor for another type of treatment.
Side effects of taking Koldakt
The medicine "Koldakt", reviews of which indicate that in some cases it provokes an increase in blood pressure, can also cause heart palpitations, drowsiness, or, conversely, sleep disturbance. Sometimes after the use of pills there is dizziness, increased nervous excitability, excessive dryness of the eye or nasal mucous membranes, pupil dilation, paresis of accommodation. There is also an increase in intraocular pressure, loss of appetite, nausea, pain in the abdomen, in the stomach area. Tablets "Koldakt" can cause anemia, quite rarely - fluid retention in the body, allergies in the form of itching, redness, rash, urticaria or angioedema. Very rarely, thrombocytopenia, leukopenia, and a decrease in the level of leukocytes appear.
Long-term treatment with the drug in isolated cases may be accompanied by hepatotoxic and nephrotoxic manifestations. Methaemoglobinemia and thrombocytopenic purpura were recorded.
Drug overdose
For a long timeoverdose may occur when using the medicine, which in most cases is due to taking large doses of paracetamol, which is part of Coldact Flu Plus. Reviews say that when using more than 10-14 g, pallor of the skin, sleep and appetite disorders, nausea, and a gag reflex may appear. The prothrombotic period increases. The activity of hepatic transaminases also increases. Hepatonecrosis, liver failure, pain in the stomach area arises and develops.
The most serious consequence of an overdose is liver failure, which often leads to encephalopathy, turbulent necrosis, and metabolic acidosis. Edema of the brain of the head is provoked and, as a result, death. Individuals who combine drinking alcohol and taking capsules can suffer serious liver damage.
In case of an overdose of the drug, gastric lavage is prescribed every six hours. It is recommended to take donators of the SH group eight hours after taking Coldact Flu Plus. The instruction states that N-acetylcesteine is administered no later than 12 hours prior to taking the last dose of the drug.
In any case, in case of an overdose of medicine, you should not prescribe treatment yourself, but you need to immediately call a specialist.
Taking with other drugs
The likelihood of an overdose with Coldact Plus (the instruction confirms this) increases when taken together with bambiturates, Difenin, Carbamazepine, Rifampicin, as well as Zidovucin and other drugsmeans that are inducers of liver enzymes.
Enhances the effect of Coldakt and the simultaneous use of sedatives, ethanol, various groups of monoamine oxidase inhibitors.
Concomitant use of antidepressants can cause fluid retention in the human body, dry mouth and lead to constipation. Glucocorticosteroid drugs increase the likelihood of developing glaucoma.
Paracetamol significantly reduces the effectiveness of uricosuric drugs.
Chlorphenamine as part of the product and when combined with drugs containing furazodid, provokes the manifestation of a hypertensive crisis, excessive excitability and hyperpyrexia.
Tricyclic psychotropic drugs significantly increase the effect of phenylephrine, and in combination with halothane can lead to ventricular arrhythmia. Reduce the effect of guanethidine, which in turn increases the α-andrenostimulation of phenylephrine.
What other effects can this medicine cause with long-term use? "Coldact Flu plus" is able to cause the anticoagulant effect of warfarin and other drugs of the coumarin group, and also increases the risk of various kinds of bleeding.
Special instructions for the use of the drug
You should not self-medicate and prescribe Coldact Flu plus on your own. The price (Russia does not produce the drug) is affordable for it, besides, it is sold from pharmacies without a doctor's prescription. But, despite this, the consultation of the therapist should be obtained before taking anydrugs, especially monoamine oxidase inhibitors.
If after using Coldact Flu (the instruction, we recall, describes in detail its correct intake), there is a chill, fever, high temperature, then you should immediately visit a doctor to clarify the course of subsequent treatment. Throughout the entire period of treatment with the drug, it is necessary to abandon the use of alcohol and drugs containing paracetamol. Do not combine medication with sleeping pills and psychotropic drugs.
When examining blood for the amount of glucose and uric acid, it is possible to change the indicators when taking Coldakt medication. The use of the drug should not be combined with driving a car. It is necessary to refrain from carrying out hazardous activities that require special concentration of attention and speed of reaction.
Coldact Flu Plus: price
Russia imports this medicine from India. The manufacturer is Ranbaxy. The cost of the drug is quite acceptable and fluctuates around 100 rubles of the Russian Federation, depending on the place of sale. The drug is available without a prescription and should be stored at a temperature not exceeding 25 ° C for no more than two years.
Produced in capsules of prolonged action, enclosed in an aluminum blister, the preparation "Koldakt". The photos below show this.
AntiFlu and TheraFlu Extratab are analogues of the drug. They contain similar active ingredients, butcost, unlike Coldact Flu Plus, almost twice as expensive. Cheaper substitutes for the drug are Rinza, Rinicold, Coldrex and others.
Coldakt Plus: reviews
Therapy with Coldact Plus medicine, the price of which is quite acceptable, caused a lot of positive feedback. For many, this is a real lifesaver that allows you to stay in line with the most dynamic lifestyle. The reviews showed that when taking the drug, relief comes the very next day. For some, ten hours later, the sore throat stops, the runny nose disappears, the cough disappears, and the temperature drops. They say that if you drink a medicine at the first sign of a cold, then only unpleasant memories will remain from the ailment, and serious consequences can be completely avoided.
There are people for whom Coldact (the price of the medicine is pleasantly surprising) did not fit. These people did not see any result, it did not affect the course of the cold. But such reviews are few and far between. Some say that the capsules are ineffective when you are already ill, and note their uselessness at high temperatures. Many do not advise resorting to the medicine without unnecessary necessity, since, according to them, it contains too much paracetamol. Many complain that the drug often causes drowsiness, in some cases there was an allergic reaction to the drug.
There is a certain category of citizens who prefer to be treated with already proven drugs, such as TeraFlu orregular paracetamol. They don't understand why they should try something else when they have their own proven drugs.
But, despite this, doctors are increasingly prescribing Coldact Plus to their patients during a cold, and those, in turn, despite initial doubts, are satisfied with the result.
