Varicose disease in its various manifestations affects about 80% of women and 30% of men. This pathology is not fatal, but requires high-quality therapy. One of the popular drugs for its treatment is "Reparil-gel". From our article you will find out for what other diseases doctors prescribe this remedy, how to use it correctly.
Description of the drug: composition and form of release
"Reparil-gel" is a drug that is produced in Germany. It has an anti-inflammatory and angioprotective effect. The pharmaceutical company produces the drug in three different forms:
- powder for injection (5 mg ampoules);
- dree;
- spray;
- gel for external use (trade name "Reparil-gel N").
The main active ingredient of the drug is escin. It is a vegetable glycoside, which is obtained from horse chestnut fruits. Escin has a strong protective effect on blood vessels. The substance is characterizedpronounced anti-exudative effect, due to which the permeability of capillary walls decreases.
Pharmacokinetic properties
According to the instructions, the drug is rapidly absorbed and then evenly distributed over the surface of the vascular bed. The highest concentration of the active substance in the body is observed 2 hours after application. The period of decay and excretion is up to 80 hours. The drug leaves the body with urine.
Indications for use
For what disorders and disorders is it advisable to use "Reparil-gel"?
- Varicose disease (pathological changes in the venous wall).
- Thrombophlebitis caused by inflammatory processes on the inner lining of blood vessels.
- Phlebitis of superficial veins.
- Pain and heaviness in the legs, severe swelling.
- Disruption of the brain due to injuries and concussions.
- Encephalitis.
- Bumps, abrasions, sprains.
It should be noted that before using the drug, you need to consult a doctor. The doctor will prescribe a regimen, tell you about possible side effects.
Mechanism of drug action
The main component of the drug - escin - has a venotonic effect, stimulating the activity of the adrenal cortex. As a result, the release of the hormones adrenaline and norepinephrine, which play the role of a kind of neurotransmitters, increases. They sequentially bind to alpha-adrenergic receptors and contribute to the narrowing of the lumen.vessels. Horse chestnut extract is also known for its ability to eliminate venous congestion, observed in varicose veins.
"Reparil-gel" inhibits the synthesis of the enzyme hyaluronidase, which is responsible for the destruction of hyaluronic acid molecules. The latter controls the preservation of the natural elasticity of the walls of the veins, the maintenance of the optimal level of fluid in the tissues of the vessels.
In general, the drug significantly improves blood flow in the limbs. It also reduces the risk of blood clots and has antioxidant properties at the same time.
Instructions for use
The doctor determines the dosage and method of using the drug, taking into account the patient's condition and the severity of his illness.
For adults with complicated thrombophlebitis and brain disorders, the medicine is prescribed only intravenously, 2 ampoules a day. For the treatment of encephalitis or hemorrhage, the dosage can be increased, but the daily amount of the drug should not exceed 20 mg.
Babies from one to 3 years old are recommended to use the medicine in the form of a spray. It is administered intravenously at the rate of 0.1 mg per kilogram of the child's body weight. In the treatment of adolescent patients, the dosage should be increased to 0.2 mg per kilogram of body weight.
Varicose disease is also one of the indications for the appointment of "Reparil-gel". The use of the drug is permissible only on the recommendation of a doctor. If varicose veins are accompanied by phlebitis or disturbances in the functioning of the valve apparatus, it is better to use a dragee or gel. Injections in this case are ineffective.
The course of treatment begins with taking one tablet after meals three times a day. As the patient's condition improves, the dosage can be reduced to two pills per day. The gel instruction recommends applying a thin layer to previously cleansed skin areas. The procedure can be repeated several times a day. Strongly rubbing the product into the skin is highly undesirable.
Contraindications
The use of the drug is not recommended for people with impaired kidney / liver function, as well as for women in a position with Rhesus conflict.
The composition of the "Reparil-gel" is described a little higher. This information is always described in detail in the instructions, this is not at all accidental. The thing is that patients with intolerance to the active components of the drug are better off refusing to use it. Otherwise, the risk of developing allergies increases. If the patient has a similar reaction, it is necessary to note the treatment and consult a doctor. He will definitely pick up an analog remedy with a similar mechanism of action.
Overdose, possible side effects
Numerous clinical trials prove that the use of the drug in recommended doses does not cause side effects. That is why it is so important to follow the instructions exactly. When taking pills with a dose of more than 20 mg per day, overdose symptoms are not excluded. If fever or nausea occurs, stop treatment immediately and consult a doctor.
As for the side effects, theyare extremely rare. The most common among them are high fever, skin rashes, nausea. No cases of anaphylactic shock have been reported.
Additional recommendations
Instructions for use reports that the drug in any of its forms enhances the effect of anticoagulants. No negative interactions with alcoholic beverages were found. However, doctors do not recommend taking the drug along with alcohol.
During pregnancy and lactation, medication is allowed, but only after consultation with your doctor. Ointment "Reparil-gel" is not recommended to be applied to the area of the mammary glands, especially when breastfeeding.
How much will the treatment cost
The drug can be purchased at any pharmacy. A prescription from a doctor is usually not required. Its cost will depend not only on the regional margin of pharmacological networks, but also on the form of implementation. For example, powder for injection costs about 55 rubles per ampoule, gel for external use - from 150 rubles. The most expensive is the tablet form of the drug. For one package (100 pills) you will have to pay a little more than 4 thousand rubles.
What patients say about the drug "Reparil-gel"
Reviews about this medication are very diverse, but in most cases they are positive. Many patients use it to treat varicose veins in courses. They note that a positive effect is manifested after a few days.after starting therapy.
Another important advantage is the composition of the drug. The presence of exclusively herbal ingredients minimizes the risk of side effects.
As noted above, the drug is marketed in several forms. Most patients prefer the gel and explain their choice by the rapid absorption of the composition. After its application, there is no film left on the skin. Many simply forget to take pills, and not everyone likes injections.
