Flamax Forte is positioned by many experts as a wonderful remedy that instantly relieves unpleasant pain, prevents the development of the inflammatory process and lowers body temperature. Experts often recommend it to patients who suffer from diseases of the musculoskeletal system. Read more about this medicine below.
Brief description of Flamax Forte
From what the above remedy helps, probably not everyone knows. It turns out that this medicine has antipyretic and anti-inflammatory properties.
The drug "Flamax Forte" ("Ketoprofen" - another international name) has three forms of release:
- solution;
- blue, biconvex film-coated tablets;
- capsules with white powder of uniform consistency inside.
Capsule contains 50 mgKetoprofen (main active ingredient), lactose monohydrate, silicon dioxide, sodium lauryl sulfate, povidone, croscamellose sodium.
One tablet of the above medicine contains 100mg of ketoprofen, macrogol 6000, talc, titanium dioxide, hypromellose, rice starch, croscamellose sodium, lactose monohydrate, sodium lauryl sulfate, povidone.
The composition of the ampoule of this drug (2 ml) includes 100 mg of ketoprofen, propylene glycol, ethanol, benzyl alcohol, water for injection, sodium hydroxide.
Flamax Forte can only be purchased with a special prescription. Tablets, reviews of which are mostly positive, cost 141 rubles. for 20 pcs. The cost of packing ampoules is 210 rubles. The price of capsules of the above drug is 125 rubles.
Keep this medicine away from children and preferably out of direct sunlight at normal room temperature.
Pharmacological action
The Flamax Forte drug, the photo of which is provided below, produces the following effects on the patient's body:
- antipyretic;
- anti-aggregation;
- anti-inflammatory;
- analgesic.
Ketoprofen with blood proteins binds 99% to albumin in the patient's body. It should be noted that after taking the drug, the concentration of the main substance in plasma is reached quite quickly.
Ketoprofen has the ability to enter the synovial fluid and connective tissues. Aftera single injection of the drug intramuscularly after a quarter of an hour in the synovial fluid, a sufficiently high concentration of it is noted. It lasts more than a day (about 30 hours). During this time, it is quite good to reduce stiffness in the joints and pain in them.
Ketoprofen is mainly metabolized in the liver. In the same place, the process of glucuronidation is carried out, as a result of which glucuronic acid and esters are formed. Further, these substances are successfully excreted by the kidneys.
Indications for use
Medicine "Flamax Forte" instructions for use recommends taking with symptoms of the following diseases:
- rheumatoid arthritis;
- osteoarthritis;
- gouty arthritis;
- myalgia;
- psoriatic arthritis;
- sciatica;
- ossalgia;
- otitis media;
- bursitis;
- arthralgia;
- tendinitis;
- neuralgia;
- sciatica;
- toothache;
- oncological diseases;
- headache;
- algodysmenorrhea.
It should be noted that the instructions for use also recommend using Flamax Forte in the complex therapy of postoperative and post-traumatic pain syndrome. In addition, the above medicine is used in childbirth as a tocolytic and analgesic agent.
Contraindications
Tablets "Flamax Forte" experts and instructions are not advised to use if the patient suffers from such diseases,like:
- hypersensitivity to individual ingredients of the drug;
- kidney diseases that are in a progressive state;
- hyperkalemia;
- gastroduodenitis during exacerbation;
- hematopoietic disorder;
- ulcer during exacerbation;
- impaired hemostasis;
- erosion of the gastrointestinal tract during the period of exacerbation;
- severe liver failure.
Instruction "Flamax Forte" also does not recommend using in the third trimester of pregnancy and during breastfeeding. It is forbidden to use the above medicine for patients after coronary artery bypass grafting and with a combination of recurrent nasal polyposis and bronchial asthma with intolerance to NSAIDs.
It should be remembered that it is not recommended to use Flamax Forte, the photo of which is provided below, for the treatment of children under 15 years of age.
With great caution, this remedy should be used to treat patients who suffer from arterial hypertension, bronchial asthma, edema, severe dental diseases, diabetes mellitus, renal failure, sepsis, chronic heart failure.
How to use
Flamax Forte injections are administered intramuscularly, as well as intravenously. The latter is carried out exclusively in the hospital. On average, the infusion of the substance (infusion) lasts about one and a half hours. The maximum administration time is 48 hours.
At the same time, the dose of the above remedy should notexceed 300 mg. If the infusion is short, 100-200 mg of the drug should be diluted in 0.9% sodium chloride solution in an amount of 100 ml. Such an infusion of funds is carried out for no more than one hour.
The next infusion of this drug is allowed only after 8 hours. If the infusion of the therapeutic agent is prolonged, then it is important to dilute it in half a liter of a special solution.
Intramuscularly, the above drug is administered a maximum of 2 times a day in an amount of 100 mg.
Capsules of the drug "Flamax Forte" patients are allowed to use only in the process of eating in a maximum amount of 2 pcs. in one go. Depending on the course of the disease, the doctor determines the appropriate dosage for a particular patient. The maximum dose of the drug per day is about 300 mg.
Flamax Forte tablets should also be taken with meals. At one time, the instruction allows the patient to use a maximum of 3 times a day, one pill each.
Specialists note that an overdose of the above medicine is not too dangerous. It is accompanied by the following symptoms:
- short of breath;
- dizzy;
- abdominal pain;
- bleeding;
- headache;
- vomit.
Treatment in this case is symptomatic. That is, the patient should first of all do a gastric lavage and prescribe sorbents.
Special Instructions
Patients should remember and strictly observe some measuresPrecautions:
- simultaneous therapy with the above drug and Warfarin requires strict medical supervision;
- this medicine perfectly masks the symptoms of many infectious diseases;
- during treatment, it is important for the patient to control peripheral blood counts;
- you need to carefully monitor the work of the kidneys and liver when therapy is carried out with the drug "Flamax Forte";
- reviews of experts and instructions recommend not to practice long-term treatment with the above remedy and use it in minimal amounts to reduce the risk of side effects from the digestive system;
- if it is necessary to determine 17-ketosteroids, the patient should cancel this drug within two days (that is, 48 hours);
- in some cases, during therapy with Flamax Forte, the patient's concentration may worsen (this should be remembered when driving vehicles).
Side effects
Specialists note that in some cases, some patients have experienced serious side effects when using the above medication. Scientists admit that their appearance may be due to the action of ketoprofen.
So, this medicine may cause the following side effects:
- dyspepsia, gastritis, belching, abdominal pain, diarrhea, nausea, constipation, stomatitis, vomiting, anorexia, increased appetite, rectal bleeding, dry mouth, GI perforation, liver dysfunction, melena, excessive thirst,hematemesis, peptic ulcer, occult bleeding, intestinal ulceration, cholestatic hepatitis, salivation;
- nervousness, dizziness, blurred vision, vertigo, hearing loss, taste disturbance, retinal hemorrhage, conjunctivitis, malaise, amnesia, pigmentation changes, CNS depression, confusion, eye pain, abnormal dreams, insomnia;
- peripheral vascular disease, increased blood pressure, anemia, agranulocytosis, increased heart rate, hypocoagulation, thrombocytopenia, worsening heart failure, hemolysis, tachycardia;
- dyspnea, rhinitis, epistaxis, hemoptysis, laryngeal edema, pharyngitis, bronchospasm;
- increased blood urea nitrogen, abnormal liver function, edema, hematurgia, menometrorrhagia, interstitial nephritis, renal failure, nephrotic syndrome;
- alopecia (exfoliation) skin rash, pruritis, eczema, purpura, anaphylaxis, excessive sweating, myalgia, weight gain, allergic reactions.
Specialists warn that when observing the symptoms of the above diseases, the patient should definitely visit the doctor and tell him about the he alth problem. This medicine should be stopped.
Interaction with other drugs
If the patient is taking other medications while taking the above drug, they should inform the doctor.
It should be remembered that the above remedy enhances nephrotoxiceffect of loop diuretics. In addition, the effectiveness of uricosuric drugs is significantly reduced when they are used simultaneously with Flamax Forte tablets.
Expert reviews also note that the above drug enhances the effects of ethanol, anticoagulants, antiplatelet agents, fibrinolytics.
With the simultaneous combination of Flamax Forte with corticotropin, corticosteroids, ethanol, NSAIDs, the patient may suddenly experience bleeding in the gastrointestinal tract, ulcers will appear, and kidney function will be impaired.
The drug "Flamax Forte" reduces the effectiveness of diuretics and antihypertensive drugs.
Bleeding can also occur if the above medicine is used simultaneously with the following:
- Heparin.
- Thrombolytics.
- "Cefotetan".
- "Cefoperazone".
- Antiplatelet agents.
- Cefamandole.
When treating with this drug, it is very important for the doctor to recalculate the doses of hypoglycemic agents, including insulin, because their effect is significantly increased.
In addition, the above medicine increases the hematotoxicity and myelotoxicity of drugs. Also, this drug increases the blood concentration of verapamil, nifedipine, methotrexate, lithium preparations.
Absorption of Flamax Forte is reduced if it is included in therapy with antacids and colestyramines.
If you mix the above drug with tramadol in one bottle, the result is a small precipitate.
Drug "Flamax Forte":analogues
Sometimes there are situations when the patient just needs to know the analogues of the above medication. This may be due to the fact that the pharmacy temporarily lacks the necessary drug, or, for example, does not suit the cost of Flamax Forte. Indications for use, which are listed above, may also be for the following drugs:
- "Fastum gel";
- "Arquetal";
- "Profenid";
- "Artrum";
- "Quickgel";
- "Ketonal";
- "Ketospray";
- "Ketonal uno";
- "Artrosilene";
- "Ketonal duo";
- "Oruvel";
- "Flexen".
It should be noted that they produce the same therapeutic effect on the patient's body as the Flamax Forte drug. But before using a substitute for this medicine, you need to consult your doctor.
Reviews about the drug
Satisfied patients leave quite a lot of positive feedback about the above preparation. People claim that this medicine is just an excellent pain reliever. For example, a woman writes about the appointment of this drug after surgery to relieve pain. The injection worked instantly, she almost immediately got to her feet and began to move normally. The woman did not feel pain, there was no discomfort.
Some men write that after grabbing their backs in the country, they can’t straighten upcould. Tried many different remedies, but nothing helped. My back hurt terribly. Only Flamax Forte was able to relieve pain. Their reviews claim that after the first injection, the pain subsided within 20 minutes and did not bother all night. Therefore, this category of patients claims that injections are an excellent tool that maintains a therapeutic effect for a long time.
There are also responses from people who have used the above drug in therapy. People write that this medicine instantly relieves pain during attacks of chondosis. But some patients complain that the drug Flamax Forte, although it relieves pain perfectly, still causes side effects in some cases. For example, after these injections, weakness occurs in the body and a person wants to lie down a bit. Therefore, if the patient was injected with this remedy, he needs to refrain from driving for at least an hour or two.
Flamax Forte is highly effective and is completely safe for the patient. It perfectly relieves severe pain, even if it is in an exacerbated period. In addition, the drug perfectly normalizes body temperature and prevents the development of the inflammatory process.
