Over the past 5-10 years, the demand for immunostimulating drugs has risen sharply. These are natural or synthetic agents that can have a regulatory effect on the body's defenses. On the territory of Russia, this group of medicines has significant sales volumes, second only to antibiotics and cancer drugs. One of its popular representatives is Sodium nucleinate. This is an immunostimulating drug with a wide spectrum of activity.
General information
The drug goes on sale in two dosage forms: tablets and powder for suspension. Pills are film-coated, packaged in 50 pieces per pack. One tablet contains 250 mg of active ingredient. Its name is the same as the trade name of the drug. Excipients include: paraffin, magnesium carbonate, starch, titanium dioxide, beeswax. Powder for suspension is sold in 10 ml vials. One package contains 50 such vials. Each vial contains 500mg active.
Pharmacological properties
"Sodium nucleinate" has a wide spectrum of action. Its components accelerate regeneration, normalize the function of the bone marrow, and activate the formation of leukocytes. The drug is also responsible for stimulating the natural immune processes in the body. Its action is aimed at combining blood components responsible for maintaining tissue defenses, restoring the work of macrophages.
Sodium nucleinate, which is part of the drug, increases the body's antitoxic resistance. At the same time, it reduces the immunosuppressive properties of antibiotics, hormones and cytostatics. Numerous medical studies confirm the ability of the drug to regenerate tissues in many diseases, including ulcerative colitis.
Indications for use
Tablets "Sodium Nucleinate" instruction recommends taking in the following cases:
- for the treatment of secondary immunodeficiency disorders accompanying the natural aging process;
- to correct agranulocytosis;
- as part of the complex treatment of infectious diseases occurring against the background of immunodeficiency conditions.
Drug in powder form is actively used to treat the following disorders:
- agranulocytosis, lymphocytopenia, leukopenia;
- dystrophic and ulcerative disorders;
- chronic alcoholism;
- elimination of intoxication of the body;
- periodontal disease;
- violation of phosphorus metabolism;
- diseases accompanied by immunodeficiency (tuberculosis, rheumatism, pneumonia, etc.).
In addition, the use of "Sodium Nucleinate" is indicated for the prevention of complications of bacterial etiology and wound healing after surgical interventions.
Dosing regimen
According to the annotation, this drug should be taken orally immediately after meals. Adults are not recommended to exceed the daily dosage of 2 g. It should be divided into four equal doses. The average duration of treatment is usually 10 days. If necessary, the doctor can increase the duration of treatment up to 6 weeks or three months.
To prevent intoxication of the body, "Sodium nucleinate" instructions for use recommend using it in the form of a suspension (1-1.5 g per day). The average duration of the course of admission is three weeks. This therapy can be repeated every six months.
Elderly patients with low immunity are recommended to take the drug at a dosage of 1-1.5 g per day. The duration of therapy is three weeks. Similar therapy should be repeated in autumn and spring. It can be supplemented with multivitamin complexes, but before that you need to consult a doctor.
Athletes are also prescribed the drug in the form of a suspension. The daily dosage is 1.5 g per day, it must be divided into four doses. Usually the course of treatment occurs during the competition.
Contraindications
Summary does not recommend the use of "Sodium nucleinate" during the treatment of malignant lymphomas and leukemias. The drug is strictly contraindicated for pregnant women and young children.
Adverse reactions
Hypersensitivity to the substances that make up the medication can provoke an allergic reaction. Usually it is manifested by rashes on the skin, severe itching and irritation. In such a situation, you should consult a doctor to replace the treatment or adjust it. "Sodium nucleinate" can cause increased sweating, bradycardia, CNS depression. Information on overdose with the subsequent development of complications has not been recorded.
Analogues
Not all patients are suitable for the drug described in the article. Some have side effects. Others cannot afford treatment due to financial problems, because the cost of the drug varies from 1,500 to 2,000 rubles. Therefore, consumers are forced to look for analogue means. It is not recommended to approach this issue on your own. Only a doctor can prescribe this or that medication. What analogues does "Sodium Nucleinat" have?
Among the variety of drugs with a similar effect, Likopid and Imunofan deserve special attention. These are immunomodulators of endogenous origin. Consider each of them in more detail:
- "Likopid". The drug is included in the complex therapy of diseases accompanied by secondaryimmunodeficiency. It can be used by adults and children, but it is better for pregnant and lactating ladies to refuse. At the beginning of treatment, an increase in temperature to 38 degrees is permissible. The disorder resolves on its own, drug withdrawal is not required. If he alth problems persist for several weeks, you should visit a doctor. The cost of pills depends on the amount of active substance and is 250-1500 rubles.
- "Imunofan". It is an immunostimulating drug with antioxidant and hepatoprotective effects. It is prescribed for the prevention and treatment of chronic inflammatory diseases of various etiologies. The medicine can be used during pregnancy, but always under the supervision of a doctor. The price varies from 430 to 550 rubles.
The described medicines are not full synonyms of "Sodium Nucleinate", but are characterized by similar pharmacological properties. In addition, the cost of analogues is several times lower, which makes them affordable for the average patient.
Consumer opinions
What do patients say about treatment with Sodium Nucleinate? Reviews of real consumers reveal all the advantages and disadvantages of this immunomodulator. It often happens that the description of the drug is delightful, and the experience of use is simply disappointing.
Given the pharmacological properties and indications for use, the drug should be prescribed everywhere. However, the opinion of doctors on this issue is not so positive. Reliable evidence of high efficiency is not presented. In other words,it is impossible to be sure that after treatment the immunity of a person will increase. In parallel, there are positive reviews of people, where they talk about the miraculous properties of the medicine.
Interesting is the opinion of other patients who talk about the serious consequences of using an immunomodulator. After the course of treatment, some of them began to lose their hair. Doctors suggest that Nucleinat stimulated hematopoiesis, but at the same time significantly depleted iron reserves in the body. As a result, there was a failure in metabolism, total baldness began. These examples are very revealing for other patients. You can not start therapy without consulting a specialist. Otherwise, you can cause irreparable damage to the entire body, even harm your he alth.
