"Akriderm GK" is a drug of combined action for external use in dermatology. The therapeutic effect of the drug is determined by the active active ingredients that make up its composition. According to the instructions, "Akriderm GK" has anti-inflammatory, anti-allergic, antifungal and antimicrobial activity.
- Betamethasone dipropionate has an anti-inflammatory, anti-allergic effect.
- The antibiotic gentamicin has a bactericidal effect and is active against pathogens of many infectious diseases.
- The antimycotic drug clotrimazole blocks the growth of the cell membrane of fungi.
When using Akriderm GK in prescribed doses, the absorption of active substances into the bloodstream through the skin is negligible (recommended for children from two years old).
Pharmacology
"Akriderm GK" recognized as localdrug with multiple actions:
- anti-inflammatory,
- antiallergic,
- antipruritic,
- antifungal,
- decongestant.
The mechanism of action of the drug is based on its ability to block the accumulation of leukocytes, on the release of pro-inflammatory biologically active substances in the inflammatory focus. Betamethasone, present in the composition of the drug, reduces the vascular tissue capacity and inhibits the formation of edema.
Gentamicin, which is part of the drug, is a well-known antibiotic with a wide range of bactericidal effects.
Clotrimazole, which is part of the drug, is an antifungal agent from the group of imidazole derivatives. It works by blocking the synthesis of ergosterol, which is an integral component of the fungal cell membrane.
Validity period
When the drug is used externally in therapeutic doses, the penetration of active substances into the blood is extremely insignificant. When applied to the skin, the intensity of penetration of the active ingredient, betamethasone, depends on the skin, its condition (the absence of wounds and cracks). The use of dressings significantly increases the absorption of betamethasone and gentamicin, which leads to an increased risk of negative effects.
Indications
According to the instructions for use of Akriderm GK ointment, the drug is prescribed for the following diseases.
- Dermatitis,which are acute inflammatory lesions of the skin resulting from the action of irritating factors of various etiologies on it.
- Diffuse neurodermatitis, which is a skin disease of allergic and neurogenic origin. In the occurrence of neurodermatitis, genetics plays a huge role, predisposition to atypical reactions. Symptoms of the disease, as a rule, occur against the background of stress or disorders in the activity of the nervous system. Violations in the work of the digestive system, other mental disorders are essential. Diffuse neurodermatitis is characterized by the appearance of external symptoms on a huge area of the skin. In some cases, the rash and redness may cover the entire body of the patient.
- Limited neurodermatitis, including chronic lichen.
- Eczema, which is a skin disease characterized by itching, blistering and pustules.
- Dermatomycosis (including thrush in women), which are fungal skin lesions, especially when they are localized in the groin area or large folds of the skin (in women, mainly under the breasts).
Treatment of ringworm
In the treatment of thrush, in addition to the use of Akriderm GK, it is required to drink systemic drugs. "Akriderm GK" for thrush in women is used against the background of the recommended intake of other forms of antifungal agents taken orally. Ointment for dermatomycosis is applied to the skin infected with harmful fungi. For maximum effect, apply the cream once or twice.per day in small quantities. You can rub the drug, but not necessarily. In men, thrush is located in the groin area. Preparations of other groups for thrush men should also be taken. "Akriderm GK" in this case acts as an additional local remedy. The main treatment is carried out by taking systemic medications. The duration of therapy for thrush depends on the speed of the drugs. With a mild form and a good effect of treatment, you can limit yourself to five days, in a difficult case, you need to increase the course of treatment to two weeks.
You can start treating thrush with "Akriderm GK" only after the attending physician allows such therapy. There are forms of thrush localized on the mucous membranes. In such forms of the disease, the use of Akriderm GK is irrational, since it is not recommended to be applied to mucous membranes.
Pregnant women are not recommended to treat ringworm with Akriderm GK.
Contraindications
It is worth limiting the use of Akriderm GK ointment in the presence of the following diseases:
- Skin tuberculosis.
- Syphilis and its skin manifestations.
- Chickenpox.
- Herpes.
- Skin reactions after vaccinations.
Side effects
According to the instructions, Akriderm GK can give a number of adverse reactions in the form of:
- Itching, severe burning or irritation, dry skin, folliculitis, hypertrichosis, steroidacne, hypopigmentation.
- When using closed dressings, swelling of the upper layer of the skin, infection, skin atrophy is possible.
- With long-term therapy or application to large areas of the skin surface, an increase in the patient's body weight, osteoporosis, increased pressure, edema, ulceration of the gastrointestinal mucosa, exacerbation of foci of infection, overexcitation, frequent insomnia.
Issue form
Ointment for topical application "Akriderm GK" 15 or 30 g in aluminum tubes. One tube is included in the pack.
Cream for topical application "Akriderm GK" 15 or 30 g in aluminum tubes, one aluminum tube in a cardboard box.
If the patient's skin is very dry, with many cracks and wounds, then they prefer to use an ointment, and with a weeping lesion of the skin, use a cream. For a more even distribution, it is possible to mix the drug with a fat baby cream, but mixing the cream and ointment will not work.
Dosage
According to the instructions for use "Akriderm GK" should be applied externally. Patients are required to avoid getting the medication in the eyes. It is not advised to apply Akriderm GK to mucous membranes and large areas of the skin. The drug in any form should be applied in a small layer. Most often, the patient's skin is lubricated twice a day. For example, at nine o'clock in the morning and in the evening at nine o'clock. At the first stage, a single application per day is sufficient, and if the disease is severely neglected, the attending physician may recommend a different dosage andfrequency of use.
Cream or ointment is applied to diseased skin areas in the required amount, gently rubbing, twice a day. The duration of therapy is determined individually and depends on the severity of the disease. In diseases of the skin of the feet, the average duration of treatment is from two to four weeks. If clinical improvement does not occur, the diagnosis needs to be corrected or the treatment regimen corrected. If even two weeks after the start of therapy there are no changes for the better on the skin, then the medication is stopped and the attending physician is consulted to clarify the diagnosis.
When treating genital infections, the genitals should be lubricated carefully, no more than five days. In any case, consultation with a skin specialist is required.
Overdose
When using the medication, it is possible to develop allergies, including severe burning, itching and the development of prickly heat.
With prolonged use of the drug, symptoms of hypercortisolism may develop. They are manifested in the fact that patients begin to complain of weakness, headaches, weight gain. There are cases in patients with a disease with hypercortisolism, a mental disorder occurs, sudden depressions, sleep disturbances occur.
According to patients, an overdose of Akriderm GK is treated by gradual withdrawal of the drug. With the development of reactions of severe skin sensitivity, the drug should be replaced.
Special Instructions
During pregnancy, the use of medication is allowed only in cases where the possible benefit of therapy for the expectant mothersignificantly outweighs the likelihood of negative consequences for the fetus. In such situations, the use of the drug should not be prolonged and limited to tiny areas of the skin. In the first trimester, it is better not to use Akriderm GK, since there is no evidence base about the benefits and harms of the drug. Refusal of this medication will help eliminate the risk of systemic effects on the unborn child through the woman's blood. The overall effect of the drug on the child in the early stages of pregnancy automatically increases in the presence of damage to the skin of a pregnant woman.
In addition to the possible negative impact on the child with uneven skin, negative effects can also be observed in the pregnant woman herself, which can worsen her condition quite a lot. If there is a way to stop such a medication before the twelfth week, then it is better not to use the drug.
Therapy of skin diseases during childbearing should be postponed to the last two trimesters of pregnancy. At this time, the unborn child has already formed internal organs and systems.
The most optimal period for the use of the drug is considered the latest stages of pregnancy. "Akriderm GK" in the third trimester will no longer have a negative impact on the child. After all, during the last trimester, the baby is already fully formed and just gaining weight.
The drug can be prescribed during childbearing to women with allergic and fungal skin diseases of a chronic nature, with their exacerbation. "Akriderm GK"allowed to apply to a woman. The advantage of its use is the low risk of systemic negative manifestations.
It has not been studied whether the active components of the drug are excreted in mother's milk. If necessary, according to the instructions for Akriderm GK ointment, during the period of natural feeding of the child, you should switch to artificial mixtures.
The drug can be used in pediatrics, starting from the age of two patients. It is worth noting that it should be used with extreme caution in minor patients. This is explained by the fact that the skin area in comparison with the weight of a small child is much larger than in adulthood, and the upper layer of the dermis is not sufficiently developed in children, as a result of which it becomes possible to absorb a large amount of active substances, which increases the risk of developing negative effects. Because of this, the use of the drug in children should be as short as possible. When resistant strains appear, it is necessary to stop the course of using the medication and make changes to the treatment. In case of poisoning with Akriderm GK, it is required to gradually reduce the dose of the drug until it is canceled with simultaneous therapy according to the symptoms.
Interaction with other drugs
Cases of negative interaction "Akriderm GK" with other medicines have not been recorded. But it's still worth telling the doctor about the medications you take.
Reviews
Reviews in the instructions"Acriderma GK" you will not find, on the forums, consumers leave them mostly positive:
- Many doctors believe that Akriderm GK is nothing more than a lifesaver in the external treatment of dermatoses. It has a quick, pronounced effect, quickly removes puffiness in the affected areas.
- ENT doctors, according to reviews, Akriderm GK ointment is considered a very effective drug in the treatment of ENT diseases, especially with abscesses, inflammation of the hair follicles, otitis media. The drug quickly causes an antibacterial effect.
- Dermatologists, judging by the reviews on the instructions for use of Akriderm GK, often prescribe the drug for dermatitis in large folds: under the breasts in women, in the groin area, in the area between the toes and hands.
Analogues
Akriderm GK has two main analogues: Kanzinon and Triderm.
"Canzinon" is an antifungal agent belonging to the group of imidazole derivatives. This is a cheap analogue of Akriderm GK, which can be purchased for only eighty rubles. "Canzinon", in addition to a cream or ointment, can be produced in the form of a vaginal cream or tablets. He, like Akriderm GK, treats diseases such as:
- Stomatitis.
- Fungal infection between fingers.
- Sexual infections.
- Lichen (skin disease).
- Fungal paronychia, which is a pathology associated with the development of a purulent-inflammatory process on the skin surroundingnail.
Canzinon should not be used by children under two years of age, women during menstruation and early pregnancy (first trimester).
"Triderm" is a medicine for external use on the skin. It is used to treat diseases acquired by an infectious secondary method. The drug is produced in the form of a cream, ointment. "Triderm" has shown effectiveness in the fight against the following diseases:
- Dermatitis.
- Lichen.
- Candidiasis.
- Eczema.
- Neurodermatitis.
"Triderm" is prohibited for children under two years of age.
The use of Akriderm GK analogues must be accompanied by a confirmation from the attending physician. Given all the contraindications and characteristics of the patient's disease, you can safely begin the treatment of diseases of the skin.
