In Russia, under the name "Miramistin", 2 drugs are registered - a solution for local use (manufacturer - the Russian company "Infamed") and an ointment for local and external use (manufacturer - Ukrainian pharmaceutical company "Darnitsa"). The remedy named last, some people call a cream. Officially, the drug is not considered a cream, but an ointment. "Miramistin-Darnitsa" is the full trade name of this drug.
Main component
The active substance in the preparation is benzyldimethyl [3-(myristoylamino)propyl] ammonium chloride monohydrate (miramistin). It's an antiseptic. This component negatively affects various microorganisms - gram-negative and gram-positive, anaerobic and aerobic, asporogenic and spore-forming microflora. Miramistin acts most strongly on gram-positive bacteria (streptococci, staphylococci, etc.). Active substancealso has a negative effect on mushrooms.
Miramistin improves the effectiveness of antibiotics because it makes bacteria and fungi less resistant. During the period of application of the ointment, the likelihood of infection of damaged skin areas decreases, and regenerative processes are accelerated. Tissues that have undergone necrosis, Miramistin dehydrates. This helps to form a dry scab faster.
Excipients
Miramistin contains a number of additional components. This is:
- purified water;
- macrogol 6000;
- macrogol 1500;
- macrogol 400;
- disodium edetate dihydrate;
- propylene glycol;
- poloxamer 268.
Indications for use
Ointment (cream) "Miramistin" is used in various fields of medicine:
- In traumatology, surgery. With the help of the drug, various damaged areas of the skin that have become infected are treated - trophic ulcers, bedsores, festering postoperative wounds, etc. Miramistin is also suitable for preventing re-infection of granulating wounds.
- In dermatology. "Miramistin" helps to treat skin diseases - candidiasis of the mucous membranes and skin, strepto-, staphyloderma, dermatomycosis of large folds, smooth skin and feet, keratomycosis.
- In combustiology. "Miramistin" can be prescribed as a remedy for frostbite, burns II and III A degrees. Another indication for use is the preparation of burn injuries for dermatoplasty.
Miramistin is available without a prescription, so everyone is advised to add this drug to their home first aid kit. The ointment can be used without a doctor's prescription in case of minor injuries at home or at work. "Miramistin" in such cases performs a preventive task - reduces the risk of complications of wound infection.
Contraindications
You can not use ointment (cream) "Miramistin" with individual sensitivity to the components of the drug. This contraindication is indicated in the instructions. When ignored, people experience allergic reactions.
The instructions do not indicate indications for the use of "Miramistin" for children. The thing is that the manufacturer advises using the drug only for adults, with the exception of pregnant and lactating women. The reason is that there is not enough experience in the use of ointment for the treatment of children, women during pregnancy and lactation. Experts cannot say that Miramistin is absolutely safe for these groups of patients, because during the period of use of the drug, the active substance enters the systemic circulation.
How to apply
Before starting treatment with ointment, a standard treatment of an existing wound or burn is carried out. After that, Miramistin is used. The cream is applied in several ways:
- The medicine is applied in sufficient quantity directly to the affected area. Next, to prevent infection, a sterile gauze bandage is applied.
- Smallthe amount of the drug is applied to the dressing. Next, this treated bandage is applied to the injured area, the wound.
- The tampons are impregnated with the drug. Then tampons are loosely filled with wound cavities after surgical treatment.
- If the patient has fistulous passages, then gauze turundas with Miramistin are injected into them.
The frequency of use of the drug depends on the problem. If there are wounds and burns in the 1st phase of the wound process, then Miramistin is used 1 time per day. In the 2nd phase, the drug is used 1 time in 1-3 days. The duration of treatment is determined by the dynamics of healing and cleansing of damaged skin areas.
In dermatological diseases, the drug is applied to the affected areas several times a day. If a gauze bandage impregnated with medicine is used, then it is applied 1-2 times a day. The duration of treatment can be 5-6 weeks.
Side effects and symptoms of overdose
The instructions for using Miramistin ointment indicate that side effects are possible, but you should not pay attention to them. As practice shows, in some patients with trophic ulcers and burns, the drug causes a burning sensation. This side symptom is short-lived. After some time after applying the medicine, it disappears, so if a burning sensation occurs:
- no need to abandon the use of "Miramistin";
- no need to use analgesics.
So far, specialists have not encountered overdose symptoms, because the drug is mainly used on small areas of the skin, and the active substance penetrates into the blood in a small amount. But when applying the drug to a large affected area, a little more Miramistin penetrates into the systemic circulation. Possible negative consequences are prolongation of bleeding time. With such a symptom of an overdose, either the applied dose of the ointment is reduced, or the drug is completely canceled. Doctors prescribe menadione sodium bisulfite (Vikasol), oral calcium supplements.
Drug Interactions
In the instructions for use of Miramistin ointment, the manufacturer indicated that soap solutions inactivate the drug.
If the infection has penetrated deep into soft tissues, Miramistin can be used with systemic antibiotics. In this case, the dose of antibiotics may be reduced.
Additional instructions
Ointment "Miramistin" for external use has a wide spectrum of antimicrobial activity. Due to this, it can be used before the identification of the causative agent of the infectious process. The ointment has a negative effect not only on monocultures, but also on mixed bacterial and fungal infections.
The effectiveness of Miramistin-Darnitsa is enhanced if it is applied to a wound that has been previously prepared and washed with an antiseptic solution.
Ointment reviews
There are many reviews about Miramistin creamUkrainian production. Almost all of them are positive. The advantages of the drug people include:
- low price;
- no smell;
- no pain, tingling after application.
Some people call the ointment a magic wand. It, judging by the reviews, is effective for abrasions, scratches, cuts, wounds. The ointment prevents suppuration, copes with other skin problems.
Analogues
Instead of Miramistin cream, you can use a solution for topical application, which has a similar name. It contains only 2 components - miramistin and purified water. The solution is recommended to be used:
- in the treatment of purulent wounds, purulent-inflammatory processes of the musculoskeletal system and for the prevention of suppuration;
- for the prevention and treatment of suppuration of postpartum injuries, wounds of the vagina and perineum, postpartum infections;
- in the treatment of burns;
- for the prevention and treatment of dermatomycosis, pyoderma, mycosis of the feet, candidiasis of the mucous membranes and skin;
- for the prevention and treatment of infectious and inflammatory processes occurring in the oral cavity;
- in the complex treatment of diseases such as acute and chronic otitis, sinusitis, laryngitis, tonsillitis, urethritis.
Persons looking for the safest remedy should pay attention to "Bepanten" - an analogue of Miramistin for children and adults (for everyone without exception). This is an ointment for external use.in which the active substance is dexpanthenol. Indications:
- violation of the integrity of the skin (burns, shallow wounds, abrasions);
- dry skin (this symptom can be eliminated if it is caused by external factors, dermatitis);
- Cracked nipples during lactation;
- diaper rash and "diaper" dermatitis in children.
Balsamic liniment (according to Vishnevsky), which is made on the basis of birch tar and xeroform, can also be referred to the analogues of Miramistin. The drug has an antiseptic effect, accelerates the regeneration processes. It is recommended for use in the presence of non-infected, long-term non-healing postoperative, post-traumatic wounds. During pregnancy, liniment can be used only after consulting a doctor. Before the appointment, the specialist evaluates the benefits for the expectant mother and the risk to the fetus. The use of the drug during lactation requires the abolition of breastfeeding.
Note information: the use of Miramistin in veterinary medicine
Miramistin is an effective substance. It is actively used in the treatment of not only people, but also animals. The proof of this is the fact that there is "Alezan" - a cream with miramistin and ASD-2F, ASD-3F. This is a combined antiseptic preparation intended for external use. The components of this cream fight pathogenic microorganisms, contribute to the removal of the inflammatory process, and activate regeneration processes. Alezan was developed for horses with traumatic,postoperative wounds, trophic ulcers, burns, bedsores, fistulas, dermatitis of fungal and bacterial etiology.
In conclusion, it is worth noting that Miramistin-Darnitsa is a really effective ointment. At the same time, its counterparts are no worse. For this reason, you can add any remedy intended for the treatment of wounds, burns and for the prevention of infection of skin areas to your home first-aid kit. It is especially recommended to buy such a medication for those people who have children. Every child loves to be active, and often outdoor activities and games lead to injuries and wounds. A remedy for treating wounds and burns will prevent suppuration and accelerate healing.
