"Tsiprolet": instructions for use, analogues and reviews

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"Tsiprolet": instructions for use, analogues and reviews
"Tsiprolet": instructions for use, analogues and reviews

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This article will be presented to the drug "Tsiprolet 500" instructions for use.

Most diseases are known to occur against the background of active reproduction of pathogenic bacteria. In the treatment of such diseases, antibacterial and antimicrobial drugs are often used today. "Tsiprolet" is very popular, it is often prescribed to fight infections of various origins. Quite often, patients have a question about whether the drug belongs to the category of antibiotics. This question arises due to the fact that in different sources the drug belongs to different groups. What does the instructions for use for Tsiprolet tell us?

tsiprolet instructions for use tablets
tsiprolet instructions for use tablets

Description

It is quite difficult to unequivocally answer the question of whether it is an antibiotic. Disputes about attributing it to one or another group of drugs are underway.still. "Tsiprolet" is a fluoroquinolone, the action of which is to destroy the DNA of a harmful microorganism and its further death. Fluoroquinolones are active both against those bacteria that begin to multiply actively, and those that are at rest.

According to the instructions for use for tablets "Tsiprolet", the spectrum of action of the active substances of the drug covers both gram-positive and gram-negative bacteria, which allows the use of the drug in various infectious diseases. This is the main similarity between fluoroquinolones and antibiotics.

These groups of substances differ in origin and chemical structure. Antibiotics are substances of natural origin or synthetic analogues, while fluoroquinolones do not have similar natural substances.

Thus, it is a man-made antibacterial drug.

Properties

As the instructions for use for "Tsiprolet" (500 mg) indicate, the active ingredient is ciprofloxacin, which is included in the category of fluoroquinolones. This substance has the following properties:

  1. Detrimental effect on various types of microbes.
  2. Easy penetration into tissues and cells in the human body.
  3. No habituation of pathogenic bacteria even with long-term use.
  4. No quantitative or qualitative harm to intestinal or vaginal microflora.

These are the main properties inherent in "Tsiprolet". When the active substance enters the cellbacteria, it stops the production of enzymes that are involved in the reproduction of infectious agents, which ultimately leads to the death of microbes.

In accordance with the instructions for use, "Tsiprolet" has a wide spectrum of action, so it is prescribed for the treatment of a variety of diseases. Only a limited number of bacteria are able to show resistance to its active substance. In most cases, "Tsiprolet" is prescribed at the initial stage of the disease or if other drugs have not given the expected therapeutic effect.

Ciprolet 500 instructions for use
Ciprolet 500 instructions for use

Today there are four generations of fluoroquinolones, and "Tsiprolet" is included in the group of the second of them. It fights pathogenic bacteria with a pronounced effect, namely staphylococci, Escherichia coli, streptococci, etc. The drug is quite quickly and well absorbed in the intestines, then entering the bloodstream, then spreading through tissues, bones and organs.

The drug is excreted mainly with urine, and the rest with bile and feces. The price of the drug is affordable, and it is quite effective, so it is often prescribed by patients on their own. However, this is the wrong decision, since the causative agent of the infection may be resistant to the active substance "Tsiprolet". In addition, the drug has a number of contraindications, so some groups of patients should not take it.

Indications

According to the instructions for use, "Tsiprolet" is intended for the treatment of infectious diseases of various origins, which are provokedbacteria sensitive to ciprofloxacin. The drug is prescribed in the following cases:

  1. Treatment of acute respiratory infections such as abscess, chronic bronchitis, empyema, pneumonia, infectious pleurisy, etc.
  2. Therapy of inflammatory diseases of the kidneys and bladder. Even small doses of "Tsiprolet" can eliminate cystitis and relieve inflammation in the kidneys.
  3. Gynecological and urological infectious pathologies, including sexually transmitted diseases.
  4. The drug enables effective treatment in the field of surgery. It is widely used in the treatment of carbuncles, abscesses, boils, mastitis and other diseases of soft tissues and skin of infectious origin.
  5. Infections of ENT organs (as an antibiotic).
  6. Inflammatory processes in the peritoneum, including abscess and peritonitis.
  7. Infectious pathologies of joints and bones, such as purulent arthritis, chronic or acute osteomyelitis.
  8. Eye diseases caused by infection such as conjunctivitis, keratitis, blepharitis, etc.

In the latter case, the drug is used in the form of drops. After a surgical intervention, the drug is prescribed as a prophylaxis in order to avoid the formation of a purulent infection. This is confirmed by the instructions for use for "Tsiprolet".

Contraindications

Like any other drug, it has a number of contraindications, namely:

  1. Pregnancy and lactation.
  2. Children under 18,which is due to the fact that the skeleton is actively forming in a child at this age. For children over 15 years of age, the drug can be prescribed as a last resort and under the supervision of a specialist.

If a patient has a violation in the circulatory system, epilepsy, mental disorders, atherosclerosis of cerebral vessels, then "Tsiprolet" is prescribed only according to the results of a thorough examination. It is also undesirable to take the drug to patients with a history of liver and kidney disease.

ciprolet instructions for use tablets 500
ciprolet instructions for use tablets 500

Side effects

According to the instructions for use and reviews for "Tsiprolet" (500 mg), the list of side effects of the infusion solution and tablets includes the following conditions:

  1. Central nervous system: dizziness, headache, tremor, sleep disturbance, fatigue, anxiety, increased sweating, nightmares, increased intracranial pressure, hallucinations, depression, peripheral paraalgesia, psychotic reactions with risk of self-harm, migraines, syncope, cerebral artery thrombosis.
  2. Digestive system: nausea and vomiting, abdominal pain, anorexia, flatulence, hepatitis, cholestatic jaundice, elevated liver enzymes and alkaline phosphatase, hepatonecrosis.
  3. Sense organs: impaired color perception, smell and taste, hearing loss, diplopia, tinnitus.
  4. Hematopoietic system: leukopenia, anemia, thrombocytopenia, granulocytopenia, hemolytic anemia, leukocytosis, thrombocytosis.
  5. Cardiovascular system: cardiac arrhythmias, low blood pressure, flushing of the skin on the face, tachycardia.
  6. Bone and muscle system: arthralgia, arthritis, myalgia, tendovaginitis, tendon ruptures.
  7. Urinary system: hematuria, urinary retention, urethral bleeding, dysuria, polyuria, reduced renal nitrogen excretion, interstitial nephritis.
  8. Lab indicators: elevated bilirubin, platelets, creatine and a high hypoglycemic index.
  9. Allergic reactions: shortness of breath, urticaria, pruritus, laryngeal and facial edema, eosinophilia, fever, vasculitis, petechnis, erythema nodosum, hypersensitivity to light, Stevens-Johnson syndrome, Lyell's syndrome, exudative erythema multiforme, blistering followed by bleeding, scabs of small nodules.
  10. Other adverse reactions: weakness, superinfections such as candidiasis, pseudomembranous colitis, etc.

When using the solution, local reactions may occur, manifested by burning and pain at the injection site, as well as phlebitis. As indicated in the instructions for use of "Tsiprolet", eye drops also have a number of possible side reactions:

  1. Visual organs: itching and burning, slight soreness, conjunctival hyperemia, eyelid edema, tearing, decreased visual acuity, foreign body sensation in the eyes, keratitis, corneal infiltration, the appearance of a white precipitate of a crystalline appearance.
  2. Other reactions: allergy, itching, feelingunpleasant taste in the mouth after using the drops, superinfection rarely develops.

Drug forms and dosages

The drug comes in three forms: tablets, injection and eye drops.

Tablets "Tsiprolet" according to the instructions for use are prescribed for diseases of mild and moderate severity. They are recommended for acute bronchitis, urethritis, cystitis, genital infections and prostatitis. In addition, the drug in tablets is prescribed for tracheitis, lesions of the larynx and sinusitis. Also, this drug is indicated for arthrosis and rheumatoid arthritis in the acute stage.

This confirms the instructions for use for tablets "Tsiprolet". Check out the reviews below.

It is also recommended to use tablets as a medicine for dysentery, typhoid fever, salmonellosis, as well as for chronic cholecystitis, cholangitis and duodenitis in an acute form. Also, the drug is used in the treatment of periodontitis and complicated caries.

Ciprolet eye instructions for use
Ciprolet eye instructions for use

The dosing regimen is established taking into account the type of infectious disease, the course of the disease, the weight and general condition of the patient. If we are talking about infectious diseases of the kidneys, respiratory or urinary tract with moderate severity, 250 mg is prescribed twice a day. In severe disease, the dose is doubled.

For gonorrhea, 250 to 500 mg once a day is prescribed. Enteritis, colitis and gynecological diseases, accompanied by fever, will requireintake per day 500 mg "Tsiprolet" according to the instructions for use.

Pills should be taken immediately before meals with plenty of water. The duration of therapy is calculated taking into account the severity of the disease. After elimination of all symptoms, the drug should be taken for another two days. Most often, the therapeutic course is from a week to ten days.

The solution form of the drug is used in more severe cases. As a rule, these are abdominal abscesses, adnexitis, sepsis, glomerulonephritis, pyelonephritis, infectious diseases of the upper respiratory tract. All these pathologies proceed in a severe form. Injection should be made only in stationary conditions. The dosage is prescribed by the doctor, who calculates it taking into account the age, weight and nature of the disease, as well as possible complications.

According to the instructions for use for drops "Tsiprolet", they are prescribed for infectious and inflammatory diseases of the organs of vision. These are keratitis, conjunctivitis, blepharitis, etc., and drops can also be used as a prophylactic after surgery on the eyes. The drug helps prevent the development of a secondary infection when a foreign body enters the eye or is injured. Treatment is selected depending on the severity of inflammation.

For moderate severity, it is recommended to instill two drops in each eye every four hours. In more severe cases, it may be necessary to instill eye drops every hour. The duration of such therapy is from four daysup to two weeks.

Interaction with other drugs

As stated in the instructions for use, "Tsiprolet" (500 mg), when taken simultaneously, may interact with the following substances:

ciprolet 500 instructions for use reviews
ciprolet 500 instructions for use reviews
  1. Didanosine reduces the effectiveness of ciprofloxacin.
  2. Theophylline accumulates in plasma and increases the risk of intoxication.
  3. The absorption of ciprofloxacin may be reduced when taken concomitantly with drugs containing aluminum, magnesium and iron ions, as well as antacids. Between such drugs and "Tsiprolet" there must be a break of at least four hours.
  4. Cyclosporin in combination with "Tsiprolet" enhances its toxic effect on the kidneys.
  5. Similar antimicrobial drugs increase their effect. These are drugs such as beta-lactams, metronidazole, aminoglycosides, etc.
  6. Nonsteroidal anti-inflammatory drugs, with the exception of acetylsalicylic acid, increase the risk of seizures.
  7. Plasma absorption of ciprofloxacin is increased when taken concomitantly with metoclopramide.
  8. Indirect anticoagulants prolong the bleeding period and increase their effect.

The following substances are acceptable for combination with ciprofloxacin:

  1. Infectious diseases caused by Pseudomonas - ceftazidime, azlocillin.
  2. Streptococci - azlocillin, mezlocillin and other beta-lactam antibiotics.
  3. Staphylococci –vancomycin, isoxazolylpenicillins.
  4. Anaerobic type infections - clindamycin, metronidazole.

Quite often the question arises about the compatibility of "Tsiprolet" with alcohol. It should be noted that alcohol itself is already a toxic substance, especially when it comes to large doses. Such abuse can lead to serious consequences for the body in general and the liver in particular.

In the instructions for use for tablets "Tsiprolet" (500 mg), hepatitis is listed among the side effects. This is due to the hepatotoxic effect that the drug can have. Accordingly, alcohol consumption during antimicrobial treatment may exacerbate this adverse reaction. Thus, alcohol and this drug are absolutely incompatible, and it is dangerous to use them at the same time.

ciprolet tablets 500 mg instructions for use
ciprolet tablets 500 mg instructions for use

With this combination, the liver will suffer first of all, and after it, which is natural, all systems and organs will fail. In addition, the effectiveness of the drug is significantly reduced in combination with alcohol. In this case, pathogenic microbes are not completely destroyed and a relapse of an infectious disease is possible.

What else does the instructions for use for Tsiprolet tablets 500 mg tell us?

There is another reason why you shouldn't mix a remedy and alcohol. It lies in the fact that this combination affects the psychomotor reactions of a person, reduces coordination and concentration, and the nervous system is also depressed, which is especiallysevere cases can lead to a coma.

Analogues

"Tsiprolet" can not always be found in pharmacies. However, the pharmaceutical market is ready to offer several similar drugs that have a similar effect on the human body. So, for example, a fairly common replacement option for "Tsiprolet" is "Medociprin". It contains the same active ingredient ciprofloxacin. The drug has a very broad spectrum of action against various microbes.

Medocyprin is prescribed for the treatment of inflammatory processes caused by infection of the respiratory tract, skin, abdominal cavity, joints, bones, urinary tract, etc. "Medocyprin" is prescribed in the postoperative period as a prophylactic. In addition, the drug is used in the field of dentistry. "Medocyprin" is contraindicated in children under 15 years of age, women during gestation and lactation. In some cases, individual intolerance to the components of the drug may be observed. So it says in the instructions for use.

Tsiprolet eye drops also have analogues. The most common of them is the antibacterial drug "Ciprodox". This drug is prescribed for the treatment of diseases of the anterior chamber of the eye of an infectious nature. "Ciprodox" is contraindicated in keratitis of viral origin, as well as under the age of 15 years. This is due to the fact that at this age there is an active stage of skeletal formation. Also, the drug is contraindicated in women during pregnancy and lactation. "Ciprodox" may affect the developmentbone structure of a fetus or newborn baby.

Other analogues of "Tsiprolet" in tablets are:

  1. Ciprofloxacin.
  2. Ciprinol.
  3. Cifran.
  4. Ciprobai.

There are also similar drugs for injection:

  1. Quintor.
  2. Cyprobid.
  3. "Ifitsipro".

Common analogues of Tsiprolet drops are:

  1. Rocip.
  2. Tsipromed.
  3. Ciprofloxacin-AKOS.
ciprolet 500 mg instructions for use
ciprolet 500 mg instructions for use

Reviews

Most reviews speak of the undoubted effectiveness of Tsiprolet. The drug quickly has a positive effect on the body from the first days of treatment. Even with the use of the minimum dosage of the drug, the effect appears after 3-5 days. Such speed is an important advantage, since antibacterial drugs affect not only harmful bacteria, but also affect beneficial microorganisms.

Patients undergoing a course of treatment at the minimum dosage do not need to take additional drugs that restore the intestinal microflora. This is confirmed by the instructions for use for tablets "Tsiprolet" 500. According to reviews, another undoubted advantage of the drug is its low cost. Its price is approximately 150 rubles.

No less good reviews about Tsiprolet drops. The drug often helps to get rid of problems such as conjunctivitis and blepharitis. Side effects are quite rare and are associated,as a rule, with an individual reaction of the body to the components of the drug.

Least of all reviews can be found about the injection solution "Tsiprolet". This form of the drug is used much less frequently than tablets or drops. Yes, and preference is given to analogues in cases where it is necessary to carry out injection treatment.

Conclusions

"Tsiprolet" is a powerful and potent drug, it can cause the development of various side effects. For this reason, you should not prescribe it yourself. This drug should be prescribed by a doctor based on the results of the examination of the patient. The most common adverse reactions to taking "Tsiprolet" are nausea, diarrhea, headache. The correct dosage chosen by a specialist will avoid complications and achieve the maximum therapeutic effect.

We have reviewed the instructions for use for tablets "Tsiprolet" "500 mg", eye drops and solution.

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