Means "Biseptol" is a combined drug with antibacterial properties. It is produced by the Polish pharmaceutical company "Polfa" and is dispensed from pharmacies exclusively by prescription.
Its active ingredients perfectly fight the growth of bacteria, destroy gram-negative and gram-positive microorganisms, including those that have developed resistance to other drugs of the sulfanilamide group. In this article we will tell you everything about the drug "Biseptol": what helps, what are its indications and contraindications for use. We will also describe how and in what doses it should be used, what side effects it can have on the human body. We hope you find this information useful.
Form of release of the drug "Biseptol"
This medicinal product is produced in several versions: in the form of tablets of 120 mg and 480 mg, oral suspensions of 80 ml andampoules with a concentrate of 8 ml. Regardless of the form of release, the drug contains two main components: sulfamethoxazole and trimethoprim (400 mg and 80 mg, respectively). The suspension is prescribed for children and has a pleasant sweetish taste. In addition to active ingredients, it consists of Cremophor RH 40, sodium carboxymethylcellulose, magnesium aluminum silicate, citric acid, sodium hydrogen phosphate, m altitol, propylhydroxybenzoate, methylhydroxybenzoate, propylene glycol, purified water. Ampoules are used only for inpatient treatment. They, like the suspension, contain, in addition to the two main active, several auxiliary components: propylene glycol, sodium hydroxide, benzyl alcohol, ethanol, sodium pyrosulfate and water for injection. Tablets have a round flat shape, white-yellowish color and engraved "Bs". In addition to active ingredients, they consist of potato starch, talc, magnesium stearate, polyvinyl alcohol and other components.
Pharmacological action
The drug "Biseptol" has a bacteriostatic effect on various types of pathogens. Sulfamethoxazole disrupts the metabolism of bacteria, including preventing the synthesis of dihydrofolic acid in their cells. Trimethoprim prevents the formation of nucleic acids necessary for the growth and reproduction of microorganisms, which leads to their rapid death. The active components of Biseptol tablets are absorbed in the small intestine. They penetrate into the fluids and tissues of the body: into the kidneys, lungs, tonsils, prostate gland, vaginal andbronchial secret. Sulfamethoxazole and trimethoprim are passed through the placental barrier and during lactation can be excreted in breast milk. 60 minutes after taking the drug, the concentration of active substances in the blood reaches the limit value. The therapeutic effect lasts for 12 hours. The drug is excreted from the body within 10-12 hours, mainly with urine. So, we examined what effect the drug "Biseptol" has. From what it helps, we will tell further.
In what cases do doctors prescribe the drug "Biseptol"?
The drug destroys various gram-negative and gram-positive bacteria and even some pathogenic fungi. It is effective against pathogens such as Haemophilus influenzae, Escherichia coli, Klebsiela, Proteus, Enterobacter, Morganella, Streptococcus, Salmonella, Legionella, Toxoplasma, Neisseria. It is also active against chlamydia and vibrio cholerae. A wide range of pathogenic microorganisms sensitive to the active complex of sulfamethoxazole and trimethoprim determines an impressive list of diseases for which Biseptol is prescribed. What does he help? Often this remedy is used to treat acute infections of the respiratory tract (pharyngitis, tonsillitis, pneumonia, bronchiolitis), infections of the upper respiratory tract (otitis media, chronic sinusitis). Often, doctors prescribe the drug Biseptol for bronchitis caused by bacteria. It is worth remembering that when a cough appears, acquire and usemedicine without the recommendation of a doctor is impossible. Inflammation of the bronchi can be caused not only by bacteria, but also by viruses that are resistant to the components of the tablets. In order not to harm your body, the drug "Biseptol" for coughing should be taken only after visiting a therapist. Self-treatment is unacceptable.
What do Biseptol tablets help with?
The remedy is often used to treat diseases of the urinary tract and genital organs. It is effective in the presence of urethritis, including post-gonorrheal, gonococcal infection, pyelitis, chronic pyelonephritis, prostatitis. Often the drug "Biseptol" is prescribed for cystitis. The thing is that in almost 80% of cases, the cause of infection in the urinary tract and the inflammatory process of the bladder is Escherichia coli. Biseptol tablets perfectly fight this pathogen.
However, it is worth remembering that when treating diseases of the urinary tract, you should be guided by the recommendations of your doctor. He will probably prescribe you not Biseptol tablets, but a fluoroquinolone antibiotic. Inadequate therapy and self-medication can lead to chronic diseases of the urinary tract, which are extremely difficult to treat. In addition to cystitis, the drug "Biseptol" also helps in the presence of a gastrointestinal infection: typhoid fever, bacillary dysentery, paratyphoid, cholera. It is also effective in the presence of infections of soft tissues and skin, such as furunculosis, pyoderma or abscess. Sometimes doctorsprescribe and in the treatment of meningitis the drug "Biseptol". From what it helps, we examined. Next, we describe the scheme of application, as well as talk about contraindications and possible side effects of this drug.
Instructions for use. Dosage
The duration of treatment is set for each patient individually. It can be from 5 to 14 days. Usually the daily dosage of the drug is calculated according to the following formula: 30 mg of sulfamethoxazole and 6 mg of trimethoprim per 1 kg of body weight. Babies are prescribed the drug "Biseptol" in the form of a suspension or syrup. The standard dosage for children is:
- 3 to 6 months old - 2.5 ml (every 12 hours);
- aged 7 months to 3 years - 2.5-5ml;
- aged 4 to 6 years - 5-10 ml;
- ages 7 to 12 - 10 ml.
Children 12 years of age and older and adults should use 20 ml every 12 hours. When prescribing Biseptol tablets to patients with impaired renal function, the dosage is halved.
Contraindications and side effects of the drug "Biseptol"
It is contraindicated in patients with severe disorders of the functioning of the kidneys and the hematopoietic system. The drug "Bispetol" is not recommended for people with folic acid deficiency, as well as those with hypersensitivity to active ingredients (trimethoprim and / or sulfonamides). It is not prescribed in childhood up to 3 months, duringpregnancy and lactation. With prolonged and uncontrolled use, the drug "Biseptol" can adversely affect well-being, including causing nausea, vomiting, diarrhea, gastritis. In rare cases, use may contribute to the appearance of hepatitis, acute liver necrosis, pancreatitis. Also, while taking the pills, allergic reactions may occur: hives, itching or skin rash.
The drug can also cause headache, dizziness, cause apathy and depression. Its use in high doses can develop thrombocytopenia, anemia, agranulocytosis and disrupt kidney function. Therefore, do not neglect the appointment of the attending physician and exceed the recommended dose. Stay he althy!
