The drug "Erespal" in the RLS (Register of Medicines) is listed as an anti-inflammatory and anti-bronchoconstrictor drug. Due to its activity, the production of biological substances, which play a significant role in the appearance of inflammation and bronchospasm, is reduced. To date, this medicine is one of the most effective drugs in the fight against cough, which is suitable not only for adults, but also for children from birth.
Instructions for Erespal syrup from radar and tablets will be described in detail in this article.
Composition and dosage form of the drug
The drug is available in tablets, as well as in the form of syrup. Round white tablets are film-coated. The syrup has an orange tint, there may be sediment.
The active component of "Erespal" from the radar station is fenspiride hydrochloride. Auxiliary substances are hypromellose, colloidal anhydrous silicon dioxide,calcium hydrogen phosphate, magnesium stearate and povidone. The film shell is made from titanium dioxide, glycerol, hypromellose, macrogol and magnesium stearate. The syrup is characterized by a flavoring composition with a honey aroma, in addition, the composition includes licorice root extract, vanilla tincture, sucrose, saccharin, glycerol, potassium sorbate and purified water.
Reviews on the use of "Erespal" are presented below.
Pharmacological action
Anti-inflammatory, as well as anti-bronchoconstrictor activity of the drug is due to the fact that the active substance fenspiride helps to reduce the production of a number of biologically active components that play a significant role in the formation of inflammation. These include harmful substances such as arachidonic acid derivatives, as well as free radicals. This is indicated by the instructions for Erespal from the radar.
The process of inhibition of the metabolism of arachidonic acid by the active substance is carried out due to the blockade of histamine receptors. Histamine in this case stimulates the formation of acid products. The active substance fenspiride blocks the so-called adrenergic receptors, whose stimulation is accompanied by an increase in the secretion of the bronchial glands. Thus, fenspiride helps to reduce the action of a number of factors that lead to hypersecretion of pro-inflammatory factors, as well as to the occurrence of inflammation along with bronchial obstruction. In addition, "Fenspiride" acts as an antispasmodic component.
The drug "Erespal" from RLS is well absorbed from the digestive system. The elimination process is up to twelve hours, which occurs mainly with urine.
Indications for use
Prescribe the use of 80 mg of "Erespal" (tablets) for various diseases of the upper and lower respiratory tract, namely:
- Rhinopharyngitis and laryngitis.
- Tracheobronchitis.
- Bronchitis with or without chronic respiratory failure.
- Bronchial asthma as part of complex treatment.
- Respiratory symptoms in the presence of cough, hoarseness, sore throat, whooping cough, and flu.
- Infectious diseases of the respiratory tract, which are accompanied by a cough, when standard antibiotic therapy is indicated for patients.
- Otitis and sinusitis of various etiologies.
Dosing regimen
Adult patients are prescribed eighty milligrams of the drug twice a day, or three to six tablespoons of Erespal syrup from the RLS per day. One tablespoon contains thirty milligrams of fenspiride hydrochloride, as well as nine grams of sucrose. The maximum allowable daily dose of the drug is two hundred and forty milligrams. The duration of treatment should be determined by the attending physician.
"Erespal" in the form of tablets is not suitable for children's treatment, and is also not applicable for adolescents under the age of eighteen. For this age category, the use of the drug is recommended in the form of a syrup.
Children, as well as teenagers, as a rule, "Erespal"prescribed at the rate of four milligrams per kilogram of body weight. Children under two years of age weighing up to ten kilograms are prescribed two to four tablespoons of syrup, that is, from ten to twenty milligrams a day. The product can be added to baby bottles. One teaspoon contains ten milligrams of fenspiride hydrochloride. For children from two to sixteen years old, whose weight exceeds ten kilograms, doctors prescribe two to four tablespoons of syrup per day. It must be taken before meals. It is advisable to shake the drug before use.
What else does the user manual for Erespal from the radar describe?
Drug side effects
The following adverse reactions are likely with respect to the drug:
- On the part of the heart, a moderate tachycardia can sometimes occur, whose severity will decrease with a decrease in the dosage of the drug.
- The digestive system may react with gastrointestinal disturbances, nausea, epigastric pain.
- Drowsiness can rarely occur as part of the work of the nervous system.
- Rash, erythema, urticaria or angioedema may appear on the part of the skin with excessive use of the drug.
The patient should be aware that if any adverse reactions occur, including those not mentioned above, or changes in laboratory parameters as a result of treatment, he should immediately contact his doctor.
Contraindications for use
According to the instructions for use for Erespal syrup from RLS, they should not be treated if at least one of the following contraindications is related to the patient:
- The age category is under eighteen when it comes to pills.
- Presence of hypersensitivity to the active substance, or to any of the components of the drug.
- Pregnancy period
- Breastfeeding. It is not advisable to use "Erespal" during breastfeeding, as there is no data on the penetration of the active substance into mother's milk.
In addition, care should be taken to prescribe Erespal syrup to patients whose body does not tolerate fructose, and it is also prohibited in galactose malabsorption syndrome and sucrase deficiency. Patients with diabetes are also not recommended due to the presence of sucrose in the composition of the syrup.
Advice on drug use
In order to treat children, as well as adolescents under eighteen years of age, it is necessary to use Erespal syrup.
It should be borne in mind that parabens, that is, parahydroxybenzoates, are included in the composition of the medicine in the form of a syrup, due to which the use of this medication can provoke the appearance of allergic reactions, including delayed ones.
As part of the prescription of the drug to patients with diabetes, it should be borne in mind that Erespal syrup contains sucrose.
Influence of "Erespal" on the ability to managevehicles and mechanisms
Studies related to the study of the effect of this drug on the ability of drivers to drive vehicles, as well as work with mechanisms, have not been conducted. Therefore, patients should keep in mind that the chance of developing drowsiness while taking Erespal is not excluded. In addition, at the beginning of therapy or when combined with the use of alcohol, care must be taken while driving vehicles, as well as during work that requires a high speed of motor reactions.
Overdose of Erespal
In the event that the dosing of the drug is violated, drowsiness may occur, or, conversely, arousal, as well as nausea, vomiting and sinus tachycardia.
The treatment in this situation should be gastric lavage, monitoring of electrocardiography along with maintaining the vital functions of the body.
Erespal drug interaction
Special studies on the interaction of the active component of fenspiride with other drugs have not been conducted.
Due to the likelihood of a sedative effect when using histamine receptor blockers, it is not advisable to take Erespal syrup in combination with medications that have a sedative effect on the body or together with alcohol.
Terms of dispensing from pharmacies and storage mode
This medicine is available by prescription in pharmacies. "Erespal" in the form of tablets is desirablekeep out of the reach of children. The temperature in the room should not exceed twenty-five degrees. Syrup "Erespal" does not require special conditions for its storage. The shelf life is three years from the date of production. It is strictly forbidden to use the drug after the expiration date, which is always indicated on the package.
Price
The cost of the drug is 300-350 rubles. It depends on the region and pharmacy chain.
There are also analogues of Erespal, cheaper than the drug itself. More on that below.
Analogues
Means with exactly the same effect will be:
- Eladon.
- Fespalen Solution Tabs.
- Inspiron.
- Erisspirus.
- "Epistat".
- "Fenspiride".
Analogues of syrup are:
- Erisspirus.
- Inspiron.
- Fosidal.
- "Epistat.
- Bronchomax.
Reviews about the drug "Erespal"
Patients love the medicine. Many write that this drug perfectly helps to cope with infectious diseases of the respiratory system.
True, it is noted that in some patients, while taking this medication, the pressure rises, which should simply be taken into account. In general, people are satisfied with the effect of "Erespal" and report in their reviews that it is very good in treatment.
The drug is especially successful in fighting cough, patients note that the medicine reduces its intensity on the third day, and eliminates it completely after five days. Manysatisfied with the action of "Erespal" and with bronchial asthma, which, in comparison with other less effective drugs, helps to improve the condition of the disease.
Satisfied with this drug and the parents of young children. An undoubted advantage is that Erespal syrup is allowed for babies from birth, and thanks to its pleasant taste, they drink it without whims. In addition, as people note in their reviews, this medicine does not cause allergies.
But this drug may not be suitable for everyone, for example, there are cases when beta-blockers like Erespal cause adverse reactions in people in the form of bronchospasm. If such patients take medications that relieve spasms, then they may begin tachycardia along with palpitations and agitation. Therefore, it is better for such patients to look for another cough remedy, after consulting with their doctor. As another small minus, the price of the drug is indicated.
We reviewed the information about the drug "Erespal" from the radar.