Gastroprotectors are preparations that are astringent, mucous, enveloping agents that relieve painful spasms, envelop the mucous membrane, thereby protecting it from the aggressive effects of gastric juice.
Functions of gastroprotectors
Gastroprotectors are special medicines designed to protect the delicate gastric mucosa from exposure:
- Pepsina.
- Hydrochloric acid and other aggressive compounds that can destroy the gastric mucosa.
Gastroprotectors are medicines that are used for gastrointestinal diseases such as:
- Erosion of the esophagus and stomach.
- Stomach ulcer.
- A duodenal ulcer.
Gastroprotectors are the means that:
- Increase the resistance of the mucosa to the environment.
- Mechanically protect the mucosa.
- Simultaneously protect the esophagus, stomach and intestines and increase mucosal resistanceto environmental influences.
The peculiarity of gastroprotectors is that they are based on natural preparations, without chemicals, which provides effective protection without harming other organs and without causing allergic reactions.
The list of gastroprotective drugs is quite large. Below are the most popular ones.
Ventrisol
It is used for people suffering from gastritis, gastric ulcer, inflammation of the duodenal mucosa. Accelerates the healing process of the affected areas of the digestive tract. Envelops only the ulcerated places of the stomach or duodenum. The price of "Ventrisol" is acceptable, it is an inexpensive drug.
Together with proteins formed from tissues devoid of epithelium, the drug forms a substance that cannot be dissolved. It fills the affected areas of the stomach and protects it from the damaging effects of acid. Allows damaged tissues to recover. Produced in the form of tablets. The price of "Ventrisola" is approximately 150 rubles.
It should not be used by pregnant women and mothers who are breastfeeding.
Neointestopan
The drug has an adsorbing and enveloping effect. Brings intestinal flora back to normal. Covers the stomach and duodenum with a thin film. Reduces intestinal spasms and has a positive effect on irritated gastric mucosa.
Makes the contents of the intestine thick and improvesstool consistency. It is used for food allergies and acute diarrhea caused by food poisoning, as well as for violations of the intestinal microflora.
Contraindicated in children under 3 years of age, and pregnant women should use with caution. Side effects include constipation.
You can take the medicine for no more than two days. Available in tablet form.
Analogues of "Neointestopan": "Neostopan", "Capect", "Reban".
De-Nol
This drug protects the gastric mucosa and tissues, and also neutralizes the aggressive environment. Refers to bacterial agents. The drug is capable of destroying microbial cells. The drug acts on the stomach and duodenum. Prevents the development of peptic ulcer. In the stomach becomes a colloidal solution. Thanks to this, the mucous membrane is protected from the actions of gastric juice.
The drug restores damaged stomach tissue. It has a complex effect on problems in the intestines and stomach. It has astringent, antiseptic, antibacterial and healing effect. The drug is available in the form of tablets.
Indications for the use of the drug "De-Nol" are as follows:
- gastric and duodenal ulcer;
- chronic gastritis;
- dyspepsia and diarrhea;
- irritable bowel syndrome.
Ulgastran
Refers to the same pharmacological group. It is used for gastric and duodenal ulcers, inflammation of the mucosa and various types of gastritis. Protects the gastric mucosa from the action of acids. Forms a protective film on damaged areas of the stomach and duodenum. Allows you to bind bile acid and pepsin.
Acts as an analgesic and allows you to speed up the recovery of damaged areas of the stomach and duodenum. The composition includes aluminum s alt. Reduces the activity of pepsin and increases the production of prostaglandins. When dissolved in an acidic environment, it forms a sticky mass with unusual properties. Creates a barrier to protect damaged areas of the stomach.
Produced in the form of tablets.
Sukrat
Mechanism of action of a gastroprotector: has a protective effect on the mucous membrane of the stomach and intestines. Produced in the form of tablets, in the package - 10 pieces.
This gastroprotective drug, interacting with the proteins of necrotic ulcer tissue, creates protective layers that help prevent the subsequent destructive action of pepsin, hydrochloric acid and bile s alt. It helps to increase the synthesis of prostaglandin, reduces the active actions of pepsin and binds a bile s alt. Inhibits active activity of pepsin by 30%. Gives a mild antacid effect.
Kaopectat
The gastroprotective medicine belongs to the antidiarrheal pharmacological group. The action of the drug is to adsorbtoxins, bacteria and gases while normalizing the composition of the intestinal flora. Due to the astringent effect, it relieves irritation of the intestinal mucosa, relieves spasms.
The medical preparation "Kaopectat" is actively used for the following gastrointestinal dysfunctions:
- acute diarrhea of various origins (infectious, allergic, medicinal);
- toxic infections;
- diseases associated with disorders in the intestinal microflora.
The drug "Kaopectat" is not prescribed for children under 3 years old, children from 3 to 6 - with caution. Contraindications for prescribing the drug may be hypersensitivity, fever.
As a side effect, constipation is noted, various allergic reactions may occur.
Venter
"Venter" is a medical preparation from the pharmacological group of gastroprotectors. This drug has anti-ulcer activity. The effect is achieved due to the formation of a protective layer on the mucosa, which counteracts the destructive effect of gastric hydrochloric acid or bile s alts on the stomach.
The medical preparation "Venter" is actively prescribed for gastric or duodenal ulcers. The drug has low absorption, 90% of it in the primary composition is excreted through the intestines, a small percentage can be excreted through the kidneys.
The drug "Venter" by pregnant women and during lactation should be used with caution and under the supervision of a physician.
Contraindications for prescribing the drug are: hypersensitivity, kidney disease, obstruction and bleeding in the gastrointestinal tract.
Possible side effects: constipation, nausea, dry mouth, slight drowsiness, slight itching.
Ankrusal
"Ankrusal" is a medical preparation from the pharmacological group of gastroprotectors, the main therapeutic agent of which is sucrolfate.
The pharmacological action of the drug is the formation of a protective layer on the walls inside the stomach and the absorption of bile s alts. "Ankrusal" is used during the course prescribed by the doctor for diseases of the digestive tract and metabolic pathologies:
- stomach ulcers or duodenal ulcers;
- peptic ulcers of unknown location;
- clinical conditions resulting from acid disturbances;
- gastroesophageal reflux;
- certain diseases of the urinary system (hyperphosphatemia in uremia).
Ankrusal is contraindicated in hypersensitivity, gastrointestinal obstruction, gastrointestinal bleeding, and pregnant women.
It should be noted that the drug is poorly absorbed, does not accumulate in tissues, and part of the drug taken (95-97%) is excreted with feces. Constipation is noted as a side effect.
Alsukral
Also included in the list of gastroprotective drugs. Refers to the type of film-forming agents, used for people suffering from an ulcerstomach.
Forms a protective film-like layer, reduces exposure to pepsin and increases Pg production. When dissolved in an acidic environment, the drug turns into a sticky mass endowed with alkaline qualities. In the stomach, it is converted to a polyanion with negative charges.
Protects damaged areas of the mucosa. It also protects the mucous membrane from exposure to aggressive substances. Weakly interacts with the mucous membrane, thus enhancing the protection of the mucous membrane and helps to protect against the action of substances such as bile.
