"Zinaprim" is a popular antibacterial drug used in veterinary practice to treat a wide range of infectious diseases in domestic and farm animals. Available in the form of a solution for injection or a fine powder to be diluted with water and taken orally.
Composition of the drug "Zinaprim"
Instructions for use speaks of the content of two main active ingredients, such as:
- sulfamethazine;
- trimethoprim.
Both substances of synthetic origin. Their combination in the right concentration enhances each other's action (synergism) and gives a powerful bactericidal effect. The mechanism of action is aimed at blocking all important physico-chemical processes occurring in the cell. Due to this, the spectrum of activity of the drug covers a large number of pathogenic bacteria that cause dangerous diseases:
- Escherichia coli;
- Clostridium spp.;
- Salmonella spp.;
- Proteus mirabilis;
- Haemophilus influenza and gallinarum;
- Streptococcus pneumoniae, pyogenes, faecalis, etc.;
- Staphylococcus aureus;
- Brucella spp.
Excipients can be citric acid, metabisulphite or sodium hydroxide, hydrochloric acid, deionized water.
Sulfatrim, Sulfprim 48, Trimethosul, Ditrim can be called as analogues. Which drug to choose in this or that case, the doctor should decide.
Indications for use
The drug is effective against a wide range of bacterial infections in domestic and farm animals. Among them:
- lung tract infections, bacterial infection of the blood (septicemia), enteritis in cats and dogs;
- pneumonia, gastroenteritis, mastitis, vibriosis, brucellosis, salmonellosis, urogenital infections, purulent inflammation, skin diseases in cattle and small cattle;
- diarrhea, mumps and pneumonia in horses;
- suppuration, malignant edema, dysentery, porcine pneumonia;
- pasteurellosis, pneumonia, rhinitis, colibacillosis, rabbit enteritis;
- infectious complications of viral diseases, pasteurellosis, salmonellosis, colibacillosis, streptococcal infections of poultry.
Judging by the reviews, this is a very effective drug. Rabbit breeders say that this remedy helps with such an ailment as coccidiosis. Howeverbefore starting treatment, be sure to consult with a veterinarian.
"Zinaprim": instructions for use in veterinary
The method of application varies for individual groups of animals. If necessary, consult a veterinarian first. The daily dose of the drug for cattle, goats, sheep and pigs is 1 g of powder or 1 ml of solution per 10 kg of body weight. The same ratios apply to pets. At first, the interval between doses should be at least 12 hours. The duration of such treatment is from 3 to 5 days. If necessary, increase the dose of the drug "Zinaprim".
Instructions for use for rabbits suggest the use of 1 g of the product per 1 liter of drinking water on the first day of treatment. In the next 2 or 3 days, the dose is reduced by half and limited to only a liter of water per day, with the Zinaprim drug dissolved in it.
Instructions for use for birds are similar. However, it is forbidden to use it for the treatment of laying hens, as the product sticks to the eggs, which makes this food unsafe. For the treatment of disorders of the gastrointestinal tract of chickens, both powder and solution of the drug "Zinaprim" can be used. Instructions for use for chickens are similar to those for adult birds.
Solutions are prepared daily in an amount that satisfies the natural needs of the animal. For the period of treatment, the diluted drug should bethe only source of drinking water. Those who met all of the above requirements, in the reviews most often characterize the drug as effective and efficient.
Being in the body
The drug is rapidly absorbed through the gastrointestinal tract or injection site and distributed throughout the body in the shortest possible time, penetrates into all tissues and organs. Most of sulfamethazine and trimethoprim are administered in the urine as compounds after some time, a smaller part - in the bile.
The components of the drug can settle in the tissues for a long time. For this reason, meat and milk of animals treated with Zinaprim should not be eaten. Instructions for use warns that animals should be slaughtered for meat only after 5 days have passed from the moment the product was used. Do not eat the eggs of birds that have undergone treatment. "Zinaprim" is a veterinary drug and, according to the degree of influence on the human body, was classified as a hazard class 3.
Side effects and contraindications
Accurate and conscientious observance of all recommended doses of application does not bear a negative result. However, prolonged use may lead to diarrhea, vomiting, nausea, kidney failure, and indigestion caused by Zinaprim.
Instructions for use warns of the danger of intoxication whenoverdose. In this case, pathological damage to the tissues of the kidneys and a violation of their work occurs. If this happens, the medication should be stopped immediately and appropriate antidotes administered to the affected animal. In the event of the appearance of unpleasant symptoms with full observance of all prescribed doses, individual intolerance to any components is possible.
Animals suffering from renal and hepatic insufficiency should be given the drug with great care, as this can cause serious malfunction of these systems. During pregnancy and breastfeeding, Zinaprim should not be used.
Medication Precautions
The instructions for use indicate the need to comply with basic hygiene measures. Before and after using "Zinaprim" you need to thoroughly wash your hands and exposed parts of the body to prevent the penetration of the drug into the human body or contact with the mucous membranes of the eyes and nose. You should also take care that this product is stored at home at the right temperature and out of the reach of children.
When using the powder, it is necessary to prevent it from getting on the skin, using protective gloves. It is advisable not to smoke, drink or eat during the procedure. It is not recommended to work with this tool for pregnant and lactating women. And also apply the drug near food, tableware, household appliances. Entry into the body"Zinaprima" can cause severe poisoning. If this still happens, you need to see a doctor.
