An effective antiviral therapeutic and prophylactic agent that allows you to fight herpes infection, herpes zoster, nonspecific colpitis and vaginosis, papillomavirus infection, is the drug "Epigen". Patient reviews indicate that the drug helps to get rid of discomfort in the genital area, is used to treat cervical erosion.
Composition and release form
The medicine is produced in the form of a spray (gel) intended for local and external use. The product is contained in vials equipped with a nozzle for vaginal use. The active ingredient is glycyrrhizic acid. Auxiliary components include propylene glycol, tween-80, folic, ascorbic, fumaric, maleic acids.
Pharmacological properties
Due to the presence of glycyrrhizic acid, which is isolated from licorice root, the drug "Epigen" (reviews saythis) has immunomodulatory, antipruritic, regenerative, anti-inflammatory, antiviral properties.
The drug has a detrimental effect on the RNA and DNA of many viruses (varicella, herpes simplex, various papillomaviruses, cytomegalovirus). The antiviral effect of the agent is associated with the indexing of interferon. The drug causes viral replication in the early stages. This occurs as a result of a selective dose-dependent slowdown of phosphorylating kinase P.
The drug, interacting with viral structures, changes the phases of their cycle, resulting in irreversible inactivation of free viral particles. The agent blocks the penetration of viral proteins into the cell, disrupting the ability of microorganisms to synthesize new viral particles. The drug has immunomodulatory and anti-inflammatory properties. It slows down the activity and formation of phospholipase and prostaglandins in activated peritoneal macrophages, accelerates the movement of leukocytes to the affected area, and activates oxygen-dependent mechanisms of phagocytosis.
The drug has a membrane-protective effect, reduces the intensity of lipid oxidation by binding toxic oxidation products and free radicals. The regenerative properties are associated with improved mucosal and skin recovery.
Epigen is an intimate spray (reviews confirm this fact), very easy to use, and its action begins from the first seconds after irrigation. The active substance accumulates when used externallyin the affected areas. Due to the slow absorption, glycyrrhizic acid practically does not enter the systemic circulation.
Indications for use
The drug is prescribed for the treatment of herpesvirus infection (primary acute and recurrent), which is caused by the herpes simplex virus type 1 and 2. Effectively copes with the remedy "Epigen"-gel (reviews of doctors testify to this) as part of a complex treatment for herpes zoster caused by the Varicella Zoster virus.
The drug is used for the treatment of papillomavirus infection, treatment and prevention of cervical pathology and genital warts, prevention of recurrence of infections caused by cytomegalovirus, papillomavirus, herpes.
The drug is used for the treatment and prevention of conditions that are accompanied by a decrease in local immunity. As part of the combined and complex treatment, the drug is prescribed for vaginal dysbacteriosis, bacterial vaginosis, vulvovaginal candidiasis, nonspecific colpitis.
Used "Epigen"-spray for erosion. Patient reviews say that the remedy effectively eliminates discomfort. The medicine restores tissue, suppresses pathogenic microbes, and prevents the formation of a malignant process.
"Epigen" is an intimate gel (patient reviews provide information about this), which allows you to cope with discomfort in the genital area, accompanied by dryness, burning, itching, and also in hypoestrogenic conditions. The drug is used inpreventive purposes during sexual intercourse (to prevent sexually transmitted viral infections).
How to use
Before use, the bottle with the medicine must be shaken, during the procedure it should be kept upright. Thus, the drug "Epigen" from thrush is used. Patients' reviews say that it must be applied to the entire affected surface, holding the can at a distance of 5 cm. The optimal therapeutic dose is 2 clicks on the valve.
Intravaginal administration of the product is carried out using the supplied vaginal nozzle. It is presented in the form of a hollow tube 7 cm long, at the opposite ends of which there is a valve and a sprayer. Before use, the spray valve is removed from the balloon and a nozzle is put on, which is injected into the body, producing 1-2 injections. This allows you to evenly apply the medicine to the internal genital organs. After the procedure, you should remain in a supine position for 10 minutes; for hygienic purposes, it is recommended to wash the nozzle with soap and warm water.
"Epigen intimate" (reviews of the male part indicate this), in addition to external use, they are injected 2 times per procedure into the opening of the urethra by means of a spray bottle, which is held at a distance of 1 cm from the organ. According to a similar scheme, the medicine is used for clinical extragenital manifestations of herpes.
Treatment regimens
With cytomegalovirus infection and genital herpes, the remedy is used infor two weeks, 5 times a day. The spray is applied both externally and intravaginally. After localization of the recurrence, the drug is used three times a day for 10 days. To prevent the recurrence of these diseases, the medication must be used in the morning and evening from the 20th day of menstruation until they end.
When shingles is required to apply the drug "Epigen" 6 times a day. Patients' reviews say that after using the medicine, the amount of rash decreased significantly, and they used the spray until all signs of the disease disappeared.
When papillomas are located in the perianal region, near and directly on the genitals themselves, the medication is prescribed 6 times a day. Procedures are performed within a week. To prevent the progression of papillomavirus infection, you should use a spray before and after sexual intercourse, as well as 3 times a day when provoking factors appear: overwork, stress, taking cytostatics, antibiotics, microflora disorders, respiratory viral infections.
For the treatment of vaginosis, nonspecific colpitis, the "Epigen-gel" remedy (doctors' reviews and their prescriptions indicate this) should be used vaginally for a week. If there is no improvement, the course of treatment is repeated after 10 days.
For manifestations of discomfort in the genital area, characterized by dryness, burning and itching, as well as as a result of ovarian failure, the drug is prescribed 2 times a day for three weeks.
Contraindications
It is not recommended to use the drug for individual intolerance to glycyrrhizic acid and other components. With caution, you should use the drug "Epigen" during pregnancy. Reviews of patients say that the medicine helps well with the manifestations of thrush, allows you to protect against infection before childbirth. You can use the medicine during the entire period of pregnancy and lactation according to absolute indications. The conducted studies did not establish the teratogenic and embryotoxic effects of the drug.
Side effects of "Epigen"
Reviews of patients indicate a good tolerance of the drug. In rare cases, allergic manifestations (including contact dermatitis) may occur.
Special Instructions
For the effective action of the medicine, the affected areas should not be washed. If signs of irritation, intolerance appear, it is necessary to stop using the Epigen medication (intimate gel). Reviews say that in rare cases, suppuration may form in the affected areas, as well as an unpleasant odor. In such situations, you should contact a specialist.
Drug Interactions
The drug can be used when taking the main groups of medicines (painkillers, anti-inflammatory, antiseptics, antibiotics), which are used for additional therapy of the above diseases. While taking antiviral drugs (interferon alfa, iodouridine, acyclovir)there is an increase in their action. During the treatment of a viral infection with Epigen, it is not recommended to take interferonogens (tilorone, cridanimod).
Epigen medicine (intimate spray): reviews
Patients leave conflicting reviews about a drug. In some cases, no improvement was observed after its use, in others, patients praise the spray. Especially a lot of reviews about the favorable disposal of thrush with the help of medicine. People say that after several procedures, burning and itching disappeared. Many talk about plans to use the drug as a preventive measure, which is especially important in the spring, when immunity is weakened.
Some patients say they used the medicine during pregnancy. Moreover, the spray was advised to them by doctors, since it contains licorice and lactic acid, there are no dyes and fragrances. Women report that they used the medicine throughout their pregnancy and continue to do so at the present time. Thanks to the drug, they forgot about irritation and dryness in the intimate area.
Analogues and price
Glycyrrhizic acid is a structural analogue of the drug "Epigen". According to the pharmacological action, the preparations "Vagikal", "Vagilak", "Laktonorm" have similar properties. The same active substance - licorice root extract - is also contained in the drugs "Glycyram" and "Epigen Labial", but the indications for these medicines are different. Women leave feedback that ashygiene product, you can use glue mousse, gel "Nivea", "Lactacid". The cost of the Epigen spray is about 700 rubles.
