There are many indications for the use of a local anesthetic. In medical practice, drugs are widely used that can cause blockade of nerve nodes and peripheral nerves. Anesthetics are also very popular in cardiology practice. They are used for the treatment and prevention of ventricular arrhythmias that accompany acute myocardial infarction, with glycoside intoxication and anesthesia. Quite often, doctors use Lidocaine Hydrochloride (2%) and analogues of this medication. For example, Candibiotic, Luan, Lykain, Versatis, Helikain and Milgamma.
Basic information
The drug belongs to the group of local anesthetics, antiarrhythmic drugs. Available in the form of a clear solution for injection, colorless and odorless. The main component of the drug is lidocaine hydrochloride in the amount of 100 and 20 mg per ml. According to its chemical structure, the drug belongs to acetanilide derivatives. Renderspronounced local anesthetic and antiarrhythmic effect on the patient's body. The action occurs by reducing nerve conduction, which develops due to the blockade of channels in nerve endings and fibers. The effect of lidocaine develops in a fairly short period and lasts up to 90 minutes. When used locally, the medicine dilates blood vessels.
The components of the product are able to normalize the cell membrane, block sodium channels and increase the permeability of membranes for potassium ions. Accelerates repolarization in the ventricles the drug "Lidocaine hydrochloride" in ampoules. The action of the product has been thoroughly studied over the years.
Indications and contraindications
The medicine can be used in such cases:
- Spinal, epidural, conduction, infiltration, thermal anesthesia.
- Preventive measures for secondary ventricular fibrillation and recurrent ventricular tachycardia.
- Gastric arrhythmias resulting from glycoside intoxication.
Before starting therapy, you should carefully study all the information about the drug "Lidocaine hydrochloride". A recipe in Latin might look like this: Rp.: Sol. Lidokaini 10%-2ml, D.t.d. N10 in amp.
Contraindications for the medicine are as follows:
- Bradycardia.
- Sinus node weakness.
- Blockade of the ventricles of the heart muscle.
- Heart failure in both acute and chronic stages.
- Cardiogenic shock.
- Reducedpressure.
- The period of gestation.
- Breastfeeding the baby.
- Allergic reaction to product components.
Lidocaine hydrochloride is not suitable for everyone as an anesthetic. The release form does not matter. Some patients may develop allergies.
Dosage
For the above types of anesthesia, the drug is prescribed in a dose of 10 to 20 mg. The maximum daily allowance should not exceed 400 mg. In the elderly and patients with cirrhosis of the liver, the dose is set individually. As an antiarrhythmic drug, a solution of "Lidocaine hydrochloride" is administered intravenously. It is diluted with an isotonic agent until a concentration of 20 mg per 1 ml is obtained. The drug is dripped for 12 hours under the control of the pulse and ECG.
Overdose may cause the following symptoms:
- dizziness;
- nausea;
- vomit;
- bradycardia;
- collapse;
- convulsions.
When the patient feels worse, the drug is stopped. He is connected to oxygenation with oxygen and symptomatic treatment is prescribed. With severe convulsions, the introduction of diazepam is indicated. It is necessary to carefully observe the dosage for Lidocaine Hydrochloride. Instructions for use contains detailed information about the drug.
Compatibility with other drug groups
Negative consequences have interaction with the following medications "Digitoxin", "Quinidine", "Verapamil", "Procainomiom", muscle relaxants,curariform drugs. Co-administration may lead to increased drug exposure. And also to the development of side effects when using Lidocaine Girpochloride. A prescription is required. Without it, it will not be possible to purchase the drug in a pharmacy. The most popular substitutes for this remedy will be described next.
Candibiotic
The drug belongs to a group of drugs with antibacterial, anti-inflammatory, antifungal, local anesthetic properties for topical use. It is made in the form of ear drops. The main components in the composition are beclomethasone dipropionate, clotrimazole, lidocaine hydrochloride, chloramphenicol.
The medicine has the following effects:
- antifungal;
- bacteriostatic;
- anti-inflammatory;
- antiallergic;
- local anesthetic.
Kandibiotic has a greater range of effects compared to Lidocaine Hydrochloride, which is mainly used for local anesthesia. The indications for its use are as follows:
- Allergic and inflammatory pathologies of the ear.
- External acute and diffuse otitis.
- Acute otitis media.
- Chronic otitis media in the acute stage.
- Post-operative intervention on the ear.
The medical remedy "Candibiotic" is used only for ENT pathologies, in contrast to the remedy "Lidocaine hydrochloride". Instructions forapplication will help to understand the features of the use of the drug. It also has contraindications: eardrum injury, the patient's age is up to 7 years, hypersensitivity to the components.
Dosage
The drug is instilled 4 or 5 drops into the external auditory canal three times a day. Interaction with other agents has not been studied. In rare cases, an allergic reaction to the main components in the composition of the drug may occur. Recall, it includes beclomethasone dipropionate, clotrimazole, lidocaine hydrochloride, chloramphenicol. During pregnancy and lactation, the drug is prescribed at the discretion of the doctor. It should only be used when the benefit to the mother outweighs the risk to the baby. It is necessary to store the drug at a temperature of no more than 25 degrees, in a dark place and not accessible to children. The remedy "Candibiotic" is dispensed in a pharmacy by prescription. It is not advisable to use drops for children under 6 years of age. During therapy, it is necessary to follow the correct dosage and recommendations of the doctor.
Milgamma drug
Produced in the form of dragees and injections. Refers to the complex of vitamins of group B. It is prescribed for pain relief. The composition of the drug includes thiamine hydrochloride, pyridoxine hydrochloride, cyanocobalamin, lidocaine.
The drug has a beneficial effect on the body in the treatment of ailments of the nervous system and the motor apparatus. The main component enhances blood flow and improves performanceCNS.
Indications:
- Neuralgia of various kinds.
- Neuritis of the facial and trigeminal nerve.
- Osteochondrosis.
Contraindications:
- Heart failure in the stage of decompensation.
- Underage.
- Hypersensitivity to the elements in the composition.
Features of use
In case of severe pain, it is recommended to administer the drug every day for 10 days. Then, upon reaching a positive therapeutic effect, it is advisable to take the drug once or twice a week. The medicine is administered intramuscularly and deeply. Lidocaine hydrochloride (1%), which is part of the solution, relieves pain and burning in the patient at the site of a pinched nerve between the vertebrae.
Gel "Luan"
The drug is used for superficial anesthesia. Available in the form of a transparent gel. The main element in the composition is lidocaine hydrochloride. The medicine is used for local action. It has an anesthetic effect. This is due to reversible inhibition of nerve endings on the surface of the skin and mucous membranes.
When is the drug used?
Indicated for diagnostic and therapeutic endourethral and endoscopic procedures. Lidocaine hydrochloride in ampoules is also prescribed for local anesthesia. The action of the product is identical to the gel. The only difference is that the solution is administered intramuscularly or subcutaneously.
Contraindications:
- Tendency to hemorrhoidal bleeding.
- Injury to the mucous membranes.
- Hypersensitivity to drug ingredients.
Dosage
The product is squeezed directly into the urethra. At the same time massage its back wall. Next, you need to clamp the urethra with a clamp and wait 10 minutes, and then proceed to diagnostic studies. The contents of one tube with the gel is enough for manipulation and persistent local anesthesia, thanks to the ingredient called lidocaine hydrochloride. The instructions for use describe when the medicine can be used. The annotation also indicates possible side effects.
Versatis
The drug belongs to the group of local anesthetics. Available in the form of a patch of white or yellowish color. The main element in the composition of the drug is lidocaine hydrochloride at a dose of 700 mg. The size of the patch is 14x15 cm. The active ingredient is an acetamide derivative. It has membrane-stabilizing activity, causes blockade of sodium channels of excitable neuronal membranes. Does not irritate the skin.
Indications for patch use:
- pain relief from vertebrogenic injuries;
- neuralgia after a herpetic rash;
- myositis.
Topical use of the patch may well be an alternative to the use of Lidocaine Hydrochloride. Pain disappears fairly quickly. The drug is not prescribedin violation of the integrity of the skin, hypersensitivity to the main substance.
Dosage
The patch is for topical use. It is glued to the area that needs to be anesthetized. After contact with the product, wash your hands thoroughly. The drug "Versatis" can be on the skin for up to 12 hours. Then you need to take a break for half a day. Then again you have to glue the patch. If hyperemia and burning appear at the point of contact, then the system must be removed until the symptoms that have arisen disappear. Within 20 minutes after applying the patch, the patient's pain will disappear.
"Lycaine" will replace lidocaine hydrochloride
The drug belongs to the group of antiarrhythmic drugs. It is a local anesthetic derived from acetanilide. It has membrane stabilizing activity. Causes all kinds of anesthesia. It has a blockade of sodium channels of excited membranes of neurons and cardiomyocytes. The composition of the drug includes lidocaine hydrochloride monohydrate at a dose of 20 mg.
Indications:
- Treatment and prevention of ventricular arrhythmias.
- Myocardial infarction.
- Anesthesia.
- Glycoside intoxication.
- Some types of anesthesia.
- Blockade of peripheral nerves and nodes.
Contraindications:
- Shock.
- Bleeding.
- Severe pathology of the liver and kidneys.
- Pregnancy.
- Lactation.
- Low blood pressure.
- Bradycardia.
Dosage
As an antiarrhythmic agent, the drug is administered intravenously at a dose of 2mg per kg body weight of the patient. The maximum rate for one application should not exceed 80 mg. Intramuscularly administered from 2 to 4 mg per kg of body weight. The interval between injections of the drug should be at least two hours.
For local anesthesia, the drug is administered in an individual dose for each patient, depending on the method of the procedure and the time it takes to complete it. It is not recommended to take Lykain together with the following drugs:
- Beta-blockers.
- "Phenobarbital".
- MAO inhibitors.
- "Suxamethonium chloride".
- "Amiodarone".
Gel "Helikain"
The drug belongs to the group of class A antiarrhythmic drugs. It is a local anesthetic, a derivative of acetanilide. Causes all types of local anesthesia. It has membrane stabilizing activity. The medicine contains lidocaine hydrochloride.
Indications
Gel "Helikain" is prescribed in such cases:
- Treatment and prevention of ventricular arrhythmias.
- Myocardial infarction.
- Glycoside intoxication.
- Blockade of peripheral nerves and nodes.
- Local anesthesia in dentistry, obstetrics, surgery and gynecology.
Contraindications:
- Low blood pressure.
- Bradycardia.
- Cardiogenic shock.
- Severe pathology of the liver and kidneys.
- Pregnancy.
- Breastfeeding.
- Increased sensitivity to the maincomponent.
How to apply the medicine?
Gel "Helikain" is administered at the rate of 2 mg per 1 kg of body weight. The average single dose should not exceed 80 mg. The drug is administered intravenously over 5 minutes. Then shows the introduction of infusion for 12 hours. The drug dissolves in isotonic fluid.
Intramuscular injection at a dosage of 2 or 4 mg per 1 kg of the patient's body weight. The calculation of the medicine should be performed only by a doctor. In general, the gel is well tolerated, but an allergic reaction may develop in the form of a rash and redness at the injection site. The remedy is sold in a pharmacy by prescription. Do not add the solution to the blood for transfusion. The medicine is stored at a temperature not exceeding 25 degrees, in a dark, dry place out of the reach of children. It is not recommended to drive vehicles and perform work associated with risk and danger during treatment. With caution, the drug is administered to patients after 65 years of age. Patients with severe pathology of the liver and kidneys should preferably stop using the drug.
Side effects
Incorrect use of the drug can lead to the development of the following symptoms:
- migraine;
- dizziness;
- tachycardia;
- pressure reduction;
- pain in the epigastrium;
- nausea;
- sleep disorder;
- excitement;
- spine pain;
- involuntary urination;
- respiratory depression until it stops.
Before prescribing a remedy, the doctor must thoroughly studythe patient's history, contraindications, and increased risk of an allergic reaction. During pregnancy and lactation, the drug is administered only in emergency cases, when the benefit to the mother outweighs the risk to the baby.
Interaction with other drug groups
It is not recommended to take it together with the following drugs and substances:
- barbiturates;
- beta-blockers;
- MAO inhibitors;
- amiodarone;
- propafenone;
- phenytoin;
- cimetidine.
You should gently inject the solution into the forearm and neck. Especially if in these places there was previously a surgical intervention. Also, patients during spinal and epidural anesthesia who have spinal deformity should refrain from using the anesthetic in this form. If a person has never been injected with Lidocaine Hydrochloride before, a subcutaneous test is recommended to rule out an allergic reaction.
Summarize
Specialists note that in medical practice, drugs are often used, the active ingredient in which is lidocaine hydrochloride. This substance perfectly blocks the nerve endings. Due to this, the patient does not feel pain during minor surgical interventions, as well as during diagnostic procedures. However, it should be borne in mind that the described drugs also have many contraindications. It is no coincidence that lidocaine hydrochloride is dispensed in pharmacies strictly by prescription.
