Tablets "Remantadine" belong to the category of the oldest medicines that are indicated for ARVI and influenza. The drug allows you to quickly eliminate the disease, when the usual antibiotic was ineffective. From the article you will learn the mechanism of action of the drug, its therapeutic effect, dosage. And also let's figure out what Remantadine tablets are for in modern medicine.
Medication description
Remantadine tablets were patented by pharmacists in 1965 in the USA. Later, experts conducted special tests among volunteers, due to which they were able to prove the high effectiveness of the drug. Today, the drug belongs to the category of synthetic substances. This is one of the few derivatives of adamantane (a chemical compound that occurs naturally in oil). The tablets are effective in the planned prevention and treatment of type A influenza, as well as in preventing the development of the active stage of tick-borne encephalitis.
Release form andcomposition
To understand what Remantadin tablets are for, you need to study all the properties of this medication. Experts have proven that the active substance of the drug is a white crystalline powder, which dissolves well in alcohol. The final composition of auxiliary trace elements depends on the form of release. The main active ingredient of the drug is rimantadine. The composition also includes auxiliary components:
- magnesium stearate;
- cornstarch;
- colloidal anhydrous silicon dioxide;
- lactose monohydrate.
The drug comes in two forms. Capsules of 100 mg are sold in blisters. Tablets of 50 mg are packaged in blisters of 10 pieces.
Pharmacological principle of action
If a patient wants to figure out what Remantadine tablets are for, then you need to pay attention to the properties of this drug. The drug compares favorably with all analogues with a powerful antiviral effect, as it belongs to ion channel inhibitors that are built into the shell of a dangerous virus. The active substance inhibits the disease at an early stage, and also blocks the development of painful symptoms.
Pills are taken exclusively orally, the maximum effect is achieved 30 minutes after consumption. It should be noted that the active substance is characterized by slow metabolism, due to which the drug remains in the patient's blood for a long time. Reception "Remantadin" can not replace the full prevention of dangerous encephalitis. Treatment must be comprehensive. The antiviral drug is characterized by gradual absorption, it is perfectly absorbed by the intestinal mucosa. The remains of the drug are excreted from the body with urine.
Indications for use
Many patients are wondering what Remantadine tablets are for? This is a high-quality antiviral agent, the main mechanism of which is the inhibition of the initial stage of virus reproduction after its penetration into a previously he althy cell. Due to this, the transfer of genetic material by dangerous viruses to the blood cytoplasm is blocked. The universal composition of the drug significantly reduces the risk of influenza.
To understand what Remantadin tablets are from and their use by patients, you need to take into account several important nuances. Experts say that the drug is relevant in the following cases:
- In the cold season, when the epidemiological threshold rises. The drug helps to strengthen the body's immune system to minimize the risk of developing SARS.
- The drug is effective for the prevention and treatment of influenza type A.
- Doctors prescribe "Remantadine" against encephalitis of viral etiology.
The tool helps to protect a person when in contact with patients with influenza.
Contraindications
The instructions for the Remantadin tablets indicate that not all patients can take the drug. The medication is contraindicated if the patient has the following diseases and conditions:
- thyrotoxicosis;
- lactose deficiency;
- galactosemia;
- impaired glucose absorption;
- pregnancy;
- kidney failure.
In the instructions for the Remantadin tablets, the manufacturers indicated that it is better not to use this remedy for women during lactation. Otherwise, stop breastfeeding your baby.
There are a number of conditional contraindications that must also be taken into account:
- individual sensitivity of the body to the components of the drug;
- tachycardia;
- presence of chronic diseases of the digestive system;
- diseases of the cardiovascular system.
Instructions for use
The method of using Remantadin tablets has its own characteristics, which must be taken into account. The drug is best taken on a full stomach. There are some dosage recommendations:
- In the instructions for the use of Remantadine tablets by adults, it is indicated that 300 milligrams of the drug should be consumed on the first day. The next two days, the dosage should be 200 mg. At the final stage, the patient needs to take 100 mg of the drug.
- Teenagers from 11 years of age take the medicine 1 tablet 3 times a day.
- Children over 8 years of age can be given a maximum of one tablet per day, but not more than two days.
Each patient must know what Remantadin tablets help from. In the instructions for use of the drugmanufacturers have indicated that the remedy is effective during influenza epidemics. For this, patients take 50 mg of the active substance for two weeks. Adults at risk are prescribed the drug 100 milligrams 2 times a day. Treatment lasts a maximum of 15 days.
Recommendations from experts
In the instructions for the Remantadin tablets, the manufacturers indicated that the drug is taken exclusively orally to prevent the development of influenza. Pills are best consumed after meals, drinking plenty of non-carbonated water. The prophylactic course is 15 days. For the fight against influenza in the early stages during the first 24 hours, take 2 capsules 3 times a day. After an encephalitic tick bite, you must take 100 mg of medication 2-3 times a day.
Adverse reactions
After reading the instructions for the "Remantadine" tablets, one can understand that almost all patients tolerate the effects of the drug on the body well. But exceeding the allowable dosage is fraught with the development of side effects:
- insomnia;
- flatulence;
- dizziness;
- impaired concentration and psychomotor activity;
- acute abdominal pain;
- dryness of the oral mucosa;
- severe nausea, vomiting;
- mild headaches;
- significant increase in plasma bilirubin concentration.
Allergic reactions are accompanied by profuse skin rashes, itching, burning. Whenat least one side effect should be consulted with a doctor. During treatment, it is better to refrain from driving a car, as well as carrying out work that requires a person to have an increased concentration of attention. Instructions for the use of "Remantadine" tablets by adults and methods for calculating the optimal dosage help to avoid the most common mistakes.
Consequences of exceeding the allowable dosage
Numerous reviews of Remantadine tablets indicate that taking an antiviral medication should be carried out in strict accordance with the individual characteristics of each patient. Exceeding the permissible dosage and frequency of administration does not lead to an increase in the antitoxic effect. But it is fraught with the development of complications. Most often, doctors diagnose disorders in the gastrointestinal tract, pronounced allergic reactions.
Experts have not yet come up with a universal antidote for Remantadine tablets. Overdose therapy is based on gastric lavage, as well as the appointment of high-quality symptomatic drugs.
Interaction with other medicines
If you combine Remantadine and Paracetamol, then the maximum concentration of an antiviral substance in human blood plasma will be reduced by 11%. Experts recommend using other remedies to effectively fight a fever. A similar situation is observed after the use of the drug by the patient."Cimetidine", which reduces the concentration of "Remantadine" by 19%. But anabolics do not affect the intensity of the drug.
Significant reduction in the benefit of antiviral pills is observed if the patient has taken urine-modifying agents. Absorbents prevent the absorption of the active components of "Remantadin" by the body. It is better not to combine an antiviral drug with antiepileptic drugs. Hemodialysis practically does not affect the intensity of the action of the antiviral agent.
Available analogues
In modern pharmacies, each patient can purchase different types of medicines that do an excellent job with viral infections and are used to prevent SARS. The following medicines are in the greatest demand:
- Arbidol.
- Algirem.
- "Amixin".
- Kagocel.
- Rimantadine.
- Ingavirin.
- Orvirem.
- Remantadin-STI.
The choice of the drug depends on the patient's tolerance of the main components and the recommendations of the attending physician. When buying, it is better not to be guided by the price, the main thing is the healing effect.
The use of "Remantadine" during pregnancy
Until now, studies on this category of patients have not been conducted. But during an experiment on animals, specialists managed to determine that the active substance of the drug quickly penetrates the placentalbarrier into breast milk. Within 3 hours after taking the tablet, the concentration of the drug in milk exceeds the indicators of the active substance in the blood plasma. This situation is especially dangerous for a developing baby. But a pregnant woman gets a big load on her kidneys.
Adverse reactions of the body negatively affect the he alth and well-being of the expectant mother. After using the capsules, bloating, stool disturbance, increased gas formation, vomiting, and nausea may occur. In some cases, appetite may disappear, the heartbeat will increase, and insomnia will appear.
In rare cases, "Remantadine" tablets can provoke a severe course of gestosis, the appearance of cramps in the limbs of a pregnant woman, and cerebrovascular accident. Exceeding the concentration of the drug in the blood of the expectant mother is simply unacceptable. Use "Remantadin" during pregnancy is prohibited. To combat SARS, it is better to use high-quality interferons and homeopathic remedies.
Prevention and treatment of children
During the epidemic of influenza and SARS, it is small patients who are most at risk of getting sick. Universal tablets "Remantadin Avexima" can increase the protective function of the immune system in order to prevent the further spread of the disease. The drug eliminates the symptoms of diseases as quickly as possible. The product has a powerful antitoxic effect, improves the well-being of the child and promotes a quick recovery.
For preschoolers, manufacturers have providedthe presence of a special dosage form - syrup. The medication can be used to treat babies from 4 years old. Children from 8 years of age are prescribed tablets or capsules. The final treatment regimen and the optimal dosage are determined solely by the pediatrician.
The intensity of therapy depends on the age of the patient:
- Children from 3 to 4 years old on the first day are given 2 teaspoons of the drug 3 times a day. At the final stage of the therapeutic course, the child uses the medication once a day.
- From 4 to 8 years old "Remantadine" is taken 3 teaspoons three times a day. On the fourth day of the disease, the drug is used once in the morning.
The drug can be used not only to fight the flu, but also to prevent SARS.