In the treatment of diseases such as osteoporosis and tendinopathy, a special place in complex therapy is given to chondroprotectors. One of the common drugs in this group is Piascledin 300 (instructions are included in each package). This drug has not such a large list of contraindications and almost does not give side effects, therefore it is actively used in medical practice. It is prescribed for the treatment and as a prophylactic for degenerative-dystrophic diseases of the joints.
Piaskledin 300: what is it?
This is a French-made drug manufactured by Laboratoires Expanscience, which has been operating in the pharmaceutical market for over 40 years and is engaged in the production of natural medical and cosmetic products. This drug is positioned as a medicine that has a completely natural plant base, making itsafe. The instruction says that the drug does not cause side effects and an allergic reaction. The effect on the body is mild and has no withdrawal syndrome. This is indicated by the instructions for use for Piascledin 300.
Pharmacological action
This drug increases the speed and quality of metabolic processes in cartilage tissues and joints. The systematic use of the drug has an anti-inflammatory and moderately analgesic effect. The instructions for use for "Piaskledin 300" indicate that the agent inhibits irreversible destructive processes in the cartilaginous tissue of the joints. It has an auxiliary effect in restoring the motor function of the joint. The active substance of this drug contributes to the destruction of proteoglycans (substances that disrupt the cartilage), which in turn leads to the restoration of cartilage tissue and improves its mobility. The data of clinical studies conducted by the laboratory confirm that Piascledin 300 (the instruction also does not refute this fact) really promotes the regeneration of cartilage tissues and stimulates the production of collagen in chondrocytes of articular tissues.
Indications for use
This drug is prescribed as part of the complex therapy of osteoarthritis of the hip and knee joints (at all stages of the disease), osteochondrosis, tendinopathy, and also as an adjuvant in the treatment of periodontitis.
Composition
The medicine comes in capsules thatintended for oral administration. Packages come in 30 and 15 pieces. The capsule shell is white in color, it is made on a gelatin basis with the addition of titanium dioxide. They are sealed in blisters and packed in branded cardboard boxes with detailed instructions. One capsule of the drug contains 100 mg of non-pollinated compounds that are derived from soy bean oil and 200 mg of avocado oil. Auxiliary substances are represented by colloidal silicon dioxide and butylhydroxytoluene. The list of components that make up the drug must be studied before taking the medicine in order to avoid allergic reactions. This is confirmed by the instructions for use for "Piaskledin 300". The price of the drug is not the lowest. It depends on the pharmacy network and the region. On average, a pack of 30 capsules will cost you 1000-1300 rubles.
Dosage
Like all chondroprotectors, this drug is not a fast-acting remedy. To achieve the desired therapeutic effect, experts recommend a course of treatment, the duration of which should be at least six months. If there is such a need, the course of treatment should be repeated. Capsules take 1 pc. once a day with plenty of water. It is best to take the drug in the morning.
Contraindications
The first and almost the only contraindication to taking "Piaskledin 300" in the instructions indicates pregnancy and breastfeeding. In addition, the drug is notassigned to minor patients.
Side effects
Very rarely, taking this medicine can cause an allergic reaction, expressed in the form of hives. In this case, the treatment is canceled and the remedy is replaced. This is confirmed by the instructions for use for "Piaskledin 300" and reviews.
Overdose
There are no clinical data on overdoses of this drug. Capsules must be taken according to the doctor's prescription and instructions to avoid the consequences in the form of allergic reactions, dyspepsia, headaches and nausea.
Drug Interactions
This drug is successfully combined with other drugs. At the initial stage of treatment, it is often prescribed in combination with non-steroidal anti-inflammatory drugs and analgesics, which are then gradually canceled or reduced in the dose.
What is the benefit?
The main positive factor is the proven (both scientifically and according to patient reviews) the effectiveness of the use of "Piaskledin 300". The manual also focuses on this. In this regard, it makes sense to also take into account the fact that the drug is a completely natural remedy, which has a positive effect on the patient's he alth as a whole.
Flaws
This drug has a good sustained effect, but it cannot be classified as a drug that has a quick effect and is used inas an ambulance. The duration of admission is perhaps the only significant drawback of this medication, except for the cost of course. The price is certainly high, but here everyone makes his own decision, based on his abilities.
Storage method and expiry date
The drug should be stored in a dark and dry place at room temperature. The shelf life of the medicine is 36 months, after this time the capsules should not be taken.
Special Instructions
This medicinal product cannot be taken with alcohol as there is no evidence of interaction with alcohol. Taking the drug does not have a significant effect on concentration, so you can safely drive a car and engage in other activities that require concentration and speed of psychomotor reactions. This is confirmed by the instructions for use for Piascledin 300.
Analogues
There is no absolutely exact analogue with the same active substance on the pharmaceutical market, since each pharmaceutical company develops its own method for isolating or synthesizing active substances in medicines. However, on the shelves of pharmacies there is a wide variety of chondroprotectors that have an identical effect. For example, Alflutop is a 1st generation chondroprotector manufactured by the Romanian company Biotehnos S. A. This drug is based on a bioactive concentrate of small marine fish. It has a similar therapeutic effect on joints and cartilage tissue. Produced in the form of an injection solution. A significant difference may be the cost of the drug, it is higher than that of Piascledin 300, but the duration of treatment is much shorter and can be limited to five to six injections into the joint. Treatment costs almost the same amount, although the remedy has a slightly higher price. In the instructions for use of the analogue "Piaskledin 300" this is emphasized.
The American drug "Artra" is also popular. It is produced by the well-known pharmaceutical company Unipharm Inc. This drug stimulates the process of regeneration of cartilage tissues of the joints. Its main difference is that it is not a drug with a natural component. The main active ingredient of "Artra" is a synthetic substance based on chondroitin sulfate sodium and glucosamine hydrochloride. The drug has a significant number of contraindications, but its price is significantly lower.
The drug "Rumalon", presented on the Russian market, is produced by the company "Ferein". This chondroprotector is of animal origin and is a glycosaminoglycan-peptide complex based on the bone marrow and cartilage of calves. The drug helps to restore the disturbed metabolism in the cartilaginous hyaline tissue, has an anti-inflammatory effect. Available as an injection solution. Costs more than Piascledin 300.
"Dandelion P" is a Russian-made bioactive food supplement. But experts sometimes refer it to chondroprotectors of plant origin andrecommended as an adjuvant for the treatment of osteochondrosis and arthrosis. The drug has a wider spectrum of action on the body. It is also used as a choleretic, mild laxative and diuretic.
Dona, produced by the Italian company Rottapharm, is another representative of this group of medicines. The main active ingredient of this remedy is glucosamine. It has an anti-inflammatory, corrective effect on the metabolism of cartilage tissues. Available in the form of an injectable solution.
Another chondroprotector is Movex Comfort. It is manufactured in India by Sava He althcare Ltd. The drug is based on glucosamine and chondroitin. Available in tablet form, it has an anti-inflammatory and regenerative effect on the joints.
In the drug "Struktum" the active substance is also synthesized - it is chondroitin sulfate. It acts as an activator of synthesizing processes in cartilage tissues, stimulates regeneration and increases protective properties. It is used in the treatment of osteoarthritis and osteochondrosis. It is also produced in the form of capsules that are filled with powder. This is confirmed by the instructions. The price of Piascledin 300 is almost twice as high as compared to it.
Reviews of doctors
Experts say that patients who took this drug speak positively about it, noting that gradually (one and a half to two months after the start of taking) the pain in the joints disappears, and theirmobility, the quality of life improves significantly. However, it should be noted that some patients after treatment had complications of diseases of the digestive system. Therefore, it is important to first study the contraindications and instructions for "Piaskledin 300", reviews of doctors and consumers.
