Drugs against fungal disease have long flooded the pharmaceutical market. This is due to the fact that damage to the nail plate and skin of any origin is difficult to treat. Fungal disease leads to damage to the epidermis. In addition, when immunity is weakened, the infection can spread to internal organs, affecting also the respiratory, urinary systems and abdominal organs.
Symptoms of disease
Infection of the nail is manifested by the following symptoms:
- changing hue;
- seal the nail;
- appearance of roughness on its surface;
- staining;
- itch;
- reddening of the epidermis around the nail;
- skin peeling around the plate;
- dry;
- brittle nails.
Fungal medicines are effective when the following conditions are met:
- Correct dosing.
- Using a medication for a period of time prescribed by a doctor. That is, if the doctor recommends taking the drug for 5 days twice a day, then it is so, and not otherwise.
- Using the medicine of the exact company prescribed by the doctor. Because the doctor who prescribed the drug knows what to expect from this remedy and how it performs in therapy.
- Compliance with the rules of personal hygiene.
Best toenail fungus pills
Drug list:
- "Terbinafine".
- "Fluconazole".
- "Lamisil".
- "Itraconazole".
- "Ketoconazole".
- "Orungal".
What are the best pills for toenail fungus to take?
Terbinafine
Antimycotic drug that has a pathogenic effect on fungi of the genus Trichophyton, Microsporia, Epidermophytosis. Terbinafine destroys the outer membrane of the source of the fungus, which helps to disrupt its functioning and leads to gradual death.
According to reviews, these are the best tablets against toenail fungus. The cost of the drug varies from 170 to 700 rubles. The drug is recommended to be taken under the following conditions:
- fungal infections of unknown origin;
- complex therapy for ringworm;
- dermatophytosis (a collective name characterizing a group of fungal skin lesions);
- fungal foot infection;
- fungal infection of internal organs.
Terbinafine side effects include:
- urticaria (a skin lesion characterized by an itchy rash);
- anaphylactic shock (immediate allergic manifestations, a state of sharply increased sensitivity of the body);
- Quincke's edema (a reaction to the influence of various factors, often of an allergic origin);
- mental disorders;
- dizziness;
- taste disturbance;
- exacerbation of inflammation in the joints and ligaments.
All of these adverse reactions are most pronounced when using the maximum allowable daily dose. Restrictions include:
- allergic reactions;
- failure of kidney and liver function.
During pregnancy, pills are contraindicated for use. Perhaps the use of "Terbinafine" in the last three months of waiting for offspring.
The method of application depends on the clinical picture of the disease and the severity of its symptoms. For adult patients, therapy is prescribed with a minimum dose of 250 milligrams per day. With the ineffectiveness of treatment, the concentration of the drug increases by 2 times or the antimycotic agent changes. The duration of therapy varies from 14 to 180 days.
Fluconazole
These are inexpensive pills for toenail fungus. The cost of the drug varies from 40 to 270 rubles. Indications for taking the drug are the following conditions:
- cryptococcosis (an infectious disease caused by yeast fungi, characterized by lesions of the central nervous system, lungs);
- candidiasis (a group of lesions that are manifested by purulent discharge caused by yeast-like fungi of the genus Candida);
- dermatomycosis (a condition belonging to a large group of fungal diseases that affect the skin, nails, folds of the body);
- lichen versicolor (a type of mycotic diseases in which the parasite damages the stratum corneum of the dermis);
- gibert's lichen (an acute dermatological disease characterized by the appearance of pink spots on the skin of the trunk and limbs, located along the Langer lines).
This is one of the best pills for toenail fungus. The severity of side effects depends on the dosage and method of administration of the drug into the body. The following negative reactions are likely to occur:
- itching of the skin;
- pain in the gastrointestinal tract;
- nonspecific inflammatory lesions in the organs of the stomach and intestines.
Restrictions on the use of pills:
- allergic reaction;
- liver failure;
- signs of viral hepatitis;
- kidney failure;
- psoriasis (chronic non-communicable disease, dermatosis,affecting mainly the skin).
For fungal nail infections, take 150 mg tablets once a day for one month, then 150 mg once a week (1 month), then as needed. Therapy should be canceled after a he althy nail grows.
The duration of treatment for a fungal infection in young patients should be strictly calculated by a specialist, depending on the severity of the symptoms.
For fungus of the nail plate and soft tissues, the drug can be used at a concentration of up to 12 milligrams per day per 1 kilogram of the child's weight for one week.
Lamisil
Antimycotic drug, the active ingredient of which is terbinafine. "Lamisil" has a high pathogenic effect on the sources of fungal infection not only of the skin and internal organs, but also of hair and nails. Even in low dosages, the drug has a detrimental effect on the outer shell of the fungus and provokes not only the suppression of its reproduction, but also its gradual death.
Indications for the use of "Lamisil":
- fungal lesions of the nail plates;
- ringworm (damage to the skin, as well as nails and human hair, which is provoked by pathogenic fungi and is considered highly contagious);
- onychomycosis (fungal infection of the nails).
This is one of the most effective pills for toenail fungus. According to reviews and instructionsaccording to the application, it is known that the adverse reactions that the drug has depend on the characteristics of the body and chronic diseases. The following states may occur:
- allergic manifestations of local and general nature;
- loss of appetite;
- migraine;
- dizziness;
- taste bud disorders.
The following conditions serve as a restriction on the reception of "Lamisil":
- allergic reactions;
- kidney and liver disease.
For adult patients for the treatment of toenail fungus, tablets are prescribed with a minimum concentration of 250 milligrams once a day. With damage to the nail plate, the duration of therapy depends on the effectiveness of the medication. If the symptoms of the disease subside, then Lamisil should be taken until the unpleasant symptoms disappear steadily.
Ketoconazole
A powerful antimycotic agent that is used to treat common fungal diseases. "Ketoconazole" destroys the sources of the fungus, affecting the protein structure of their outer shell.
According to reviews, tablets against toenail fungus are recommended for use with severe lesions, which are caused by total damage to the plate and a number of underlying soft covers.
The big advantage of this medication is that it affects conditional and pathogenic bacteria, which, as a rule, aggravate the clinical picture of fungaldiseases and lead to a decrease in the effectiveness of some antimycotic drugs. The cost of the medication varies from 240 to 420 rubles.
Indications for use:
- infections caused by yeast-like fungi that damage mucous membranes;
- nail fungus;
- vaginal candidiasis (an infectious lesion caused by yeast-like fungi and characterized by irritation).
Side effects from the use of "Ketoconazole" depend on the concentration and duration of therapy:
- pain and discomfort in the abdomen;
- increased sensitivity of reflexes;
- vomiting and nausea;
- hair loss;
- increased body temperature;
- impotence;
- loss of sleep;
- conjunctivitis (inflammatory lesion of the mucous membrane of the organs of vision, which is provoked by an allergic reaction or infection);
- tonsillitis (an infectious disease, the leading symptom of which is an acute or chronic inflammatory process in the palatine tonsils);
- glossitis (pathological inflammation of the tissues of the tongue, which is more often a symptom of general pathologies of the body, but in rare cases acts as an independent disease).
According to the instructions, contraindications are:
- kidney disorders;
- children under 12;
- liver dysfunction;
- allergic reactions.
Use "Ketoconazole" during pregnancyforbidden. Dosage and duration of therapy is determined only by the doctor.
Adults are prescribed 200 milligrams a day. With the ineffectiveness of therapy, the concentration of the drug is increased by 2 times. If the nail is damaged, the medication is used until a he althy plate grows, the duration of treatment is at least one month.
Itraconazole
An antifungal drug that has a powerful pathogenic effect on the source of infection. The price of the medicine varies from 270 to 600 rubles.
According to the instructions for use of the drug, tablets against toenail fungus are prescribed in the presence of the following conditions:
- vulvovaginal candidiasis (the development of an inflammatory process on the mucous surfaces of the vagina, caused by the activity of infectious microorganisms belonging to fungi of the genus Candida);
- oral candidiasis;
- onychomycosis;
- histoplasmosis (an infectious disease caused by the fungus Histoplasma capsulatum);
- sporotrichosis (chronic fungal infection of the body with typical skin manifestations);
- cryptococcal meningitis (a form of the disease in which the causative agent is a deadly fungus);
- paracoccidioidomycosis (deep systemic chronic mycosis, characterized by damage to the skin, as well as mucous membranes and internal organs with the formation of granulomas and ulcers).
Adverse reactions are known from the instructions for use, whichprovokes "Itraconazole":
- impaired absorption of nutrients in the gut;
- dysbacteriosis (a condition caused by a violation of the intestinal microflora associated with a change in the species composition of bacteria);
- pain and discomfort in the abdomen;
- migraine;
- dizziness;
- allergic manifestations.
Prohibitions on the use of drugs:
- allergic reactions;
- kidney and liver disease.
During pregnancy and breastfeeding, it is contraindicated to take Itraconazole. Onychomycosis is eliminated by taking 200 milligrams of the drug per day for 3 months, then repeated therapy is carried out.
Orungal
Antimycotic agent, which is produced in the form of capsules or solution. Assign the drug "Orungal" under the following conditions:
- pityriasis versicolor (a non-inflammatory disease of the skin of a fungal etiology that affects the stratum corneum of the epidermis);
- lesion of the nail plate;
- deep visceral candidiasis;
- fungal keratitis (an inflammatory lesion that occurs in the cornea of the eye under the influence of pathogenic microflora);
- blastomycosis (a fungal disease that usually occurs in temperate climates by contact with soil, grass);
- paracoccidioidomycosis (systemic mycosis with the development of benign self-limiting lung lesions);
- systemic aspergillosis (a disease caused by various types of mold fungi that affects several organ systems simultaneously);
- histoplasmosis.
Contraindications for use and side effects of "Orungal"
According to the instructions for use, the drug is prohibited for use under the following conditions:
- breastfeeding;
- pregnancy;
- high sensitivity;
- in childhood and old age;
- cirrhosis of the liver (a pathological condition resulting from impaired circulation in the hepatic vascular system and dysfunction of the bile ducts);
- chronic kidney and heart disease.
When the nail plate on the legs is affected, take 200 milligrams twice a day for one week. Duration of therapy - 21 days.
The drug is generally well tolerated. In rare cases, the following adverse reactions may occur:
- pain in the abdomen;
- diarrhea;
- intestinal obstruction;
- nausea;
- dyspepsia (disturbance of the normal functioning of the stomach, difficult and painful digestion);
- vomiting;
- hepatitis (inflammatory liver disease, usually of viral origin);
- toxic liver damage;
- headache;
- peripheral neuropathy (damage to a conditionally isolated part of the peripheral nervous system);
- vertigo (symptom best known as dizziness, itoccurs with an ear pathological process or brain lesions);
- menstrual irregularities;
- pulmonary edema;
- congestive heart failure;
- skin itching;
- rashes;
- alopecia (abnormal hair loss, leading to their partial or complete disappearance in certain areas of the head or torso);
- photosensitivity (skin reaction to sunlight involving the immune system);
- Stevens-Johnson syndrome (an acute allergic disease characterized by rashes on the skin and mucous membranes).
Conclusion
It is not difficult to eliminate the fungal infection of the nail plate thanks to a large assortment of drugs. Many of them help get rid of an unpleasant disease in a matter of weeks.
The effectiveness of antimycotic drugs has been proven by numerous positive responses from people. It is important not to delay with therapy and immediately seek help from specialists when the first symptoms of the disease appear. The doctor will help you choose the safest and most effective medication.
