Ordinary diarrhea is often perceived not as a problem, but as a kind of misunderstanding - they say, it just happened, it will pass by itself. However, the discomfort that literally bursts into a person’s life with an acute disorder of the digestive system is far from the main cause for concern. Liquefied stool is a symptom of an insidious disease resulting from various disorders in the body.
You need to understand that prolonged diarrhea dehydrates the body much faster than a thirty-degree heat. The functional imbalance of the gastrointestinal tract leads to the fact that the lion's share of the most useful trace elements and vitamins simply does not reach the "destination". And over time, cells begin to experience a shortage of "building materials". The result of such a scenario is very deplorable, and if we are talking about a fragile child's body, then the outcome can be fatal.
To neutralize such a threat, Stopdiar is well suited (reviews from both doctors and patients are very positive) - a highly effective antibacterial drug based on nitrofuran derivatives.
Issue form
Suspension (syrup) of bright yellow color with banana smell;the original bottle is made of dark glass (container capacity - 125 ml, actual volume of liquid - 90 ml). The medicine container is placed in a cardboard box containing a double-sided measuring spoon (5 ml and 2.5 ml).
In turn, Stopdiar tablets have a lemon-colored film shell and are packaged in 24 units / blister. The geometry of the pills is standard.
Chemical composition and shelf life of the medicinal product
The component base of the Stopdiar preparation is defined by the instructions for use as follows:
- one dose of syrup (5 ml) contains 220 mg of nifuroxazide (active reagent);
- of the same active ingredient in one tablet - 100 mg.
Suspension contains banana flavor, sucrose and defoamer emulsion; per pill - talc, potato starch and magnesium stearate.
Provided that the storage temperature requirements (15-25 degrees Celsius) are met, the syrup will be good for three years, the tablets for four.
Pharmacological action of the drug
Getting into the gastrointestinal tract, nifuroxazide is practically not absorbed - it is released unchanged and thus provides the maximum concentration of the reagent in the problem area of the digestive system. Such a mechanism of contact with infectious agents guarantees a high rate of manifestation of the therapeutic effect. At the same time, Stopdiar, whose analogues often “shock” the intestinal microflora, is distinguished by its tolerantattitude towards "peaceful" bacteria. Being a derivative of 5-nitrofuran, nifuroxazide demonstrates activity against staphylococci and streptococci, and also disrupts the usual life cycle of Salmonella, Shigella and Escherichia coli.
Regular use of suspension/tablets for acute diarrhea does not lead to the development of resistant strains. Moreover, the effectiveness of therapy does not depend on the specifics of the acid-base environment in the intestinal lumen, nor on the response of pathogenic microorganisms to antibiotics.
In an unbalanced digestive system, a decrease in the level of toxins after taking Stopdiar (doctors' reviews indicate that this process is extremely fast) is achieved by inhibiting dehydrogenases and inhibiting the synthesis of protein compounds directly in bacterial cells.
Conditions for appointment
Since the Stopdiar tablets / suspension (the use of the drug is normalized by the instructions) is an intestinal antiseptic, indications for its appointment can be:
- acute or chronic diarrhea caused by pathogens sensitive to the active ingredient (nifuroxazide);
- other diseases of the gastrointestinal tract of a bacteriological nature of origin.
Among the most pronounced symptoms of infectious diseases: loose stools, severe nausea, vomiting, permanent abdominal pain, persistent flatulence.
"Stopdiar": instructions for use of tablets
There is a direct relationship between the release formdrug and those recommendations, which informs the instructions. "Stopdiar" - tablets that are intended for patients over 6 years of age and must be used without violating the integrity of the film shell (chewing the pills is not allowed). At the same time, the regimen of taking the drug does not depend on the diet and the schedule "breakfast - lunch - dinner": the medication is taken every 6 hours until the symptomatology regresses. The optimal single dose for this age group is 2 tablets (8 units / day). The duration of the course should not exceed seven days, but the control period is limited to 72 hours: if after this time the patient does not feel better, you should immediately consult a doctor to adjust the therapy.
Instructions for using the suspension
"Stopdiar" for babies (reviews of young mothers about the drug are very positive) is available in the form of a suspension, but with the same effect, the drug can be used in the treatment of older patients.
The patient is given syrup every 6-8 hours (again, without reference to food intake), while the medicine bottle is shaken vigorously in order to give the contents a homogeneous state.
Double-sided measuring spoon allows you to dose the medication in a volume of 110-220 ml, which is very convenient, based on the recommendations of the instructions. For children, depending on age, the following norms are established:
- from two to six months - 110-220 mg of syrup, twice a day;
- from six months to six years - by220 mg active fluid, thrice daily;
- over six years - 220 mg suspension, four times a day.
Contraindications for the use of medication
"Stopdiar", reviews of which are based on the personal experience of many parents (the drug is considered one of the best solutions to the complex problem of childhood diarrhea), still cannot be called a universal drug.
Prescribing this substance is not medically justified if:
- the patient has all the signs of individual intolerance to the components;
- the patient is allergic to 5-nitrofuran derivatives.
In addition, both in the case of suspension and in the case of tablets, there is a restriction on the minimum age of the patient - 2 months and 6 years, respectively. In addition, Stopdiar is a syrup (for children, the instruction introduces additional conditions of use), which is contraindicated in case of prematurity of the fetus, that is, if the young patient is 2 months old, but the birth was premature, the use of this medication can cause complications in the gastrointestinal tract.
Acceptable side effects and special instructions
Side effects of the drug "Stopdiar" instructions (reviews on this topic are very rare, because, regardless of the form of release, the medication is well tolerated by people who suffer from diarrhea and related disorders) characterizes as follows:
- increased diarrhea aggravated by painsyndrome in the abdomen (interruption of therapy is not required due to the transience of the described effect);
- shortness of breath, Quincke's edema, skin allergies (if such symptoms are detected, the drug is stopped).
Special instructions - this is a consequence of the biochemical characteristics of nifuroxazide. For example, the non-susceptibility of the main component to metabolic processes sometimes leads to the fact that pathogens of a severe form of the disease stop responding to the medication, and then the emphasis is on the parallel use of the profile antibiotic (although the use of Stopdiar with other antibacterial drugs is not recommended due to the mechanism of its reaction – total adsorption). Long-term antidiarrheal therapy based on nifuroxazide also puts forward requirements for the diet - juices, spicy and rough foods, thermally processed vegetables and fruits should be excluded from the diet.
Interaction of "Stopdiar" with other drugs
Before using, first of all, you need to understand the principles of drug interaction of the Stopdiar drug. Reviews (tablets and suspension, it must be said, were equally supported by the broad masses) often contain information that taking the described substance "put an end" to attempts to simultaneously get rid of several diverse ailments (that is, diarrhea passed, but other symptoms, drug-suppressed remained).
As mentioned above, the reason for this is the specific mechanism of contact of "Stopdiar" with other chemical compounds. BeingAs a reagent that is not subject to absorption, the drug, however, is able to concentrate the active components of other pills and syrups on its surface, and can remove them from the body in an unsplit form.
The instruction says that the interval between taking Stopdiar and oral administration of another medication should be at least 2 hours.
Opinions and comments
About the drug "Stopdiar" reviews are mostly positive. There were no serious complaints about the effect of its components on the body of a child or an adult patient on thematic forums. Almost everyone who has come across a medication talks about its effectiveness in terms of relieving acute diarrhea.
But when compared with a more expensive analogue - "Enterofuril" (under this trade name the same nifuroxazide is hidden), the opinions of patients / parents regarding the pharmacological dynamics demonstrated by "Stopdiar" were somewhat divided. Probably, the notorious question of price again played its role, because reputable doctors say that both drugs are equally effective and do not cause dysbacteriosis.
