In the recent past, "Adelfan" was one of the most common drugs used to relieve the symptoms of hypertension. It contained two active substances - reserpine and dihydralizine, which had a complex effect. They had the ability to relax the walls of blood vessels, affecting the central nervous system and reducing the number of heartbeats. Why was Adelfan discontinued? And also many people are interested in what can now replace this tool. Let's figure it out in this article.
Harm to the body
Some effects of the drug are extremely unfavorable for the body. But in the case of sudden jumps in blood pressure of uncertain etymology, "Adelfan" was indispensable and especially popular with the elderly. Side effects of the drug are quite extensive:
- Depression of the central nervous system.
- Headaches.
- Development of signs of depression.
- Spasms and convulsions.
- Heart failure, angina and heart attack.
- Irritable.
- Anxiety.
Overdose is very dangerous
Overdose could lead to slurred speech, drowsiness, dizziness and slowed motor functions. It was impossible to take this drug with epilepsy, pathologies of the heart, liver and kidneys, during pregnancy and under the age of 18 years. So, why was Adelfan discontinued?
Safer drugs
Since the drug is morally outdated and safer and more modern drugs of similar action or more effective have entered the pharmaceutical market, it was discontinued at the beginning of 2015, and at the moment it cannot be found in pharmacies.
Pharmaceutical companies have developed a structural analogue that also reduces blood pressure quickly, but does not have such strong and diverse side effects. Such a drug was Adelfan-Ezidrex, which is produced in India and practically does not differ in composition from its predecessor, but supplemented with substances that stop the harmful effects of active components. Having had the necessary effect in the body, the active substances of the drug are excreted naturally over the next day, without being able to negatively affect the internal systems of a person.
Why "Adelfan" is discontinued,interested in many.
Dosage
The new drug not only has different properties, but is also taken in different doses. The norm is no more than two tablets per day. However, sometimes one tablet taken in the morning is enough to achieve a stable antihypertensive effect. Half an hour after taking it is not recommended to eat. With regular use, the risk of sudden jumps in blood pressure is reduced for a long time.
Contraindications
Contraindications, however, the analog is no less than the original drug. No less impressive is the list of side effects that can occur in all systems of our body. However, taking "Adelfan-Ezidrex" will help to avoid anemia, dry mouth, upset stool and flushing to the face. This drug is well accepted by the organisms of people in old age and patients weakened by other diseases.
Why Adelfan was discontinued is now clear. But what to replace it with?
Analogues
In addition to Adelfan-Ezidrex, there are other generics. All of them are combined symptoms. That is, they do not remove the root cause of high blood pressure, but only quickly remove the signs of hypertension. Especially often, doctors prescribe the following drugs:
1. "Enap". Inexpensive analogue of "Adelfan", costs only 56 rubles. Lowers blood pressure without slowing down the heart rate. Acts quite gently and is relatively safe.
2."Triresid". Has the same properties as the previous preparation.
3. "Reserpine". It is used not only to relieve the symptoms of hypertension, but also for some mental illnesses as part of complex therapy. Released by prescription. Analogues and substitutes for "Adelfan" can be bought at any pharmacy.
To relieve symptoms of hypertension
The above drugs have a similar composition, being structural analogues of this drug. However, there are other drugs that relieve the symptoms of hypertension:
1. Apo-Hydro and Dichlothiazide are effective thiazide diuretics. They have a pronounced diuretic effect.
2. Tenoric, Arifon, Tenorox and Ionic are thiazide-like diuretics.
3. Furosemide and Lasix are loop diuretics. They remove excess fluids and s alts from the body.
4. "Veroshpiron" refers to diuretics that conserve potassium in the body.
Analogues in the composition of "Adelfan" reduce blood pressure due to its pronounced diuretic effect. However, they are categorically contraindicated for those who have problems with the genitourinary system. Treatment with drugs in this group has proven to be effective, along with a relatively small number of side effects and contraindications.
Other generics
Other generics of "Adelfan" are drugs, the action of which is primarily aimed at solving problems of the cardiovascular system. To theminclude:
1. "Koramin". A fairly well-known analogue, which is prescribed to accelerate the process of restoring myocardial functions during ischemia and infarction. The drug also helps with hypertension, as well as intense exercise. Coramine is not contraindicated in the elderly, it is prescribed to support the myocardium. To enhance the clinical effect, it is taken in combination with "Vasalamin".
2. "Nephrox". A popular Russian analogue of "Adelfan". It is used for the prevention and treatment of such diseases as: high blood pressure, diabetic nephropathy, atherosclerosis, azotemia, kidney failure and inflammation in the genitourinary system.
3. "Cordaflex" is prescribed for the treatment of hypertension of varying degrees of severity, with cardiac ischemia and angina pectoris. This drug quickly and effectively stops the hypertensive crisis.
4. "Krishtal" is prescribed as a prevention and treatment of ischemia, atherosclerosis, arterial hypertension, obliterating endarteritis and dyscirculatory encephalopathies. New generation analogues of Adelfan are now very popular.
5. "Verapamil". It is also prescribed for hypertension, ischemia and angina pectoris. Suitable for atrial fibrillation and flutter and supraventricular tachycardia. For the relief of a hypertensive crisis, the drug is prescribed in the form of injections. Its effectiveness has also been proven in acute coronary insufficiency and other similar conditions.
6. "Atherophyton". It contains biologically active ingredients thatrestore normal blood cholesterol levels and strengthen the walls of blood vessels. It has a preventive effect, preventing atherosclerosis, ischemia, heart failure, varicose veins and thrombophlebitis.
7. "Ebrantil". A worthy alternative to Adelfan. Produced in the form of a solution for parenteral use. Suitable for relieving hypertensive crisis. Sometimes used as a means of controlling blood pressure during operations. There are other medicines analogous to Adelfan.
8. Complex "AngiOmega". Dietary supplement, which contains niacin, vitamin E, omega-3, 6, 9 acids, policosanol and oleuropein. This dietary supplement is recommended for the prevention and treatment of atherosclerosis, ischemia, angina pectoris and brain diseases such as memory and attention impairment, forgetfulness and cerebral atherosclerosis. In addition, "AngiOmega" has a supportive effect as part of complex therapy for diabetes mellitus, hypertension, low-calorie diet, psycho-emotional stress, reduced immunity, etc.
We figured out why Adelfan was discontinued. Preparations analogues of the described medicine are given in large quantities. But all prescriptions must be done by a doctor.
