In the article we will consider the most effective drugs for osteoporosis.
Drugs are presented in a fairly wide range, however, among them it is impossible to choose the best remedy that can cure absolutely all diseases. Treatment directly depends on the degree and stage of the pathology. The choice of medicines doctors carry out taking into account the individual characteristics of the organism of a particular patient.
Drug treatment of this disease is pathogenetic in nature. Since osteoporosis is formed against the background of a decrease in bone density, its therapy is aimed at replenishing minerals, and, in addition, at increasing the strength of bone tissue. Osteoporosis requires an integrated approach from patients, as a rule, people are prescribed drugs that belong to several pharmacological groups at once.
The treatment of osteoporosis with drugs and methods of therapy will be described below.
Basictreatment principles
Fracture consolidation is an essential physiological process necessary for survival. Weak bone fusion in the body provokes not only a sharp decrease in the functional activity of the supporting and motor systems, but also significantly worsens the quality of human life. After fractures, severe deformities can occur. The main cause of such deformities may be an incorrect comparison of the bone fragment, leading to a curvature or shortening of the limb, and, in addition, to a pronounced limitation in motor activity and movement. Osteoporosis drugs restore broken bones to their former strength, preventing recurrence of chronic pathologies.
In recent decades, pharmacological drugs for the treatment of osteoporosis have been synthesized, with the use of which the relative risks of vertebral fractures have been reduced by up to seventy percent, and proximal femoral fractures by up to fifty-one percent.
Tactical treatment of osteoporosis depends on the degree of diagnosed degenerative change and the stage of the disease.
- For example, there is a primary disease that can develop during natural menopause with a decrease in the production of sex hormones in the female body. Therefore, drugs for hormone replacement therapy and bone mass building may be included in the treatment regimen.
- The secondary form of osteoporosis occurs in patients, as a rule, after taking pharmacological drugs, and, in addition, as a result of diseasesendocrine, immune, cardiac and vascular systems, as well as against the background of the development of pathologies of the digestive tract. The treatment of bone fragility is aimed at eliminating the causes of the disease.
In the main treatment, drugs are used that affect the metabolic process in the bone structure. Such medicines improve the absorption of calcium trace elements. In order to increase the therapeutic effectiveness, such drugs are used for a long time, without any interruptions. Symptomatic therapy plays a huge role, which is aimed at alleviating the well-being of a person. Non-steroidal drugs can be used along with antispasmodics, muscle relaxants, painkillers and balanced vitamin complexes.
Next, let's find out what doctors first of all pay attention to when choosing the main drugs for the treatment of osteoporosis.
What do doctors look for when choosing a medicine?
When choosing the most effective medication for osteoporosis, doctors take into account many factors, for example, it is important to pay attention to the age of the patient, the results of laboratory and instrumental studies, and, in addition, the presence of chronic pathology in history.
Therapeutic preparations must necessarily fulfill the main tasks of treatment, preventing the development of further destructive and degenerative changes in the supporting system. A properly prescribed medication can suppress increased resorption, stimulating reduced bone formation, which significantly increases bone mineral density, improving their condition.and reducing the likelihood of new fractures.
Choosing the right osteoporosis medication
An anti-osteoporotic agent must necessarily reduce the likelihood of fractures that are localized in the vertebrae and in the proximal thighs. These bone injuries are the cause of the most dramatic medical and social consequences, especially in older patients.
Effective Osteoporosis Medicines: Bisphosphonates
This category of drugs is the basic component of therapy for patients with osteoporosis. Basically, bisphosphonates are recommended for postmenopausal women. Such medicines restore bone density, preventing the occurrence of fractures. True, these drugs for osteoporosis differ in an extensive list of side effects and contraindications. It is important to note that before using medicines from the bisphosphonate group, it is necessary to perform a comprehensive examination in order to exclude all contraindications.
Which drugs are on the list of the best drugs for the treatment of osteoporosis?
Drug "Bonviva"
The active ingredient in Bonviva is ibandronic acid. Together with auxiliary ingredients in the composition, it can effectively reduce the processes of bone destruction, stopping resorption. The drug "Bonviva" is produced in tablet format, and, in addition, in the form of injections. As a rule, Bonviva pills at a dosage of 150 milligrams are enough to use only once a month, and for injection therapyform, it is recommended to perform one injection every three months.
Bonviva is prohibited for patients suffering from individual sensitivity to the ingredients of this medicinal composition. This remedy is contraindicated for pregnant women and children. Great care should be taken when taking this medicine in the presence of osteoporosis in those patients who have a history of pathology of the digestive tract.
Osteoporosis drug "Zometa"
The active ingredient in this case is zoledronic acid, which acts on osteoclasts. Release this medication in the form of a concentrate. Immediately before use, 4 milligrams of the medicinal product is diluted with 100 milliliters of saline or dextrose. This medication is administered by intravenous drip method. It is enough to put a drip only once every six months.
Medication "Aclasta"
This drug acts as an analogue of Zometa. Its main difference is its course, for example, one dropper is usually prescribed every two years. True, the opinions of experts about Aklasty differ significantly, since the drug in question has a lot of all kinds of side effects.
Foroza medicine
Foroza is produced in the form of tablets. The active ingredient is alendronate sodium. This medication is able to restore bone tissue, but it does not directly affect bone formation. This bisphosphonate is able to repair bones throughactivation of osteoclasts, but the process itself is carried out exclusively on damaged areas.
This medication has been developed and marketed exclusively for the treatment of osteoporosis. The drug "Foroza" significantly reduces the percentage of bone fractures in the presence of pathologies of any localization. Foroza treatment involves taking one tablet once a week. This dosage is enough to effectively affect the entire body.
Continuing our review of Osteoporosis Treatments.
Calcium preparations as an effective treatment for osteoporosis
Calcium citrate carbonates can regulate and optimize bone metabolism. Basically, these drugs consist solely of calcium. These tools include:
- Calcium gluconate. Among monopreparations, this one is the most affordable. The medication in question is prescribed in tablets, and, in addition, in injections for osteoporosis.
- Treatment with calcium lactate. This medical product is classified as a dietary supplement in the category of antioxidants.
- The use of calcium glycerophosphate. This mineral supplement is able to normalize tissue metabolism in tubular bones. They sell such medicine in pharmacies in the form of powder and pills. The most effective calcium preparation for osteoporosis will help you choose a doctor.
As a rule, experts recommend treating older people suffering from senile osteoporosis with calcium-based drugs. Datamedicines are suitable for the treatment of pregnant women and children.
Below, consider the best drugs for osteoporosis in women.
Use of anabolic steroids for women
Such drugs are prescribed by specialists in cases where treatment lasts for years. Steroids can accelerate bone growth by slowing down metabolic processes. Use these funds to treat osteoporosis among females in menopause.
Adverse reactions may include hirsutism along with voice changes. Sometimes patients may complain about changes in the subcutaneous and fat layer.
What is the most effective injection for osteoporosis?
In treatment, long-acting anabolic steroids, such as Retabolil, are the most preferred. The active ingredient in Retabolil is nandrolone decanoate. This medicine is released in the form of injections for injections.
Among the adverse reactions during treatment with such drugs, patients have serious disturbances in the endocrine system. In this regard, during therapy, you need to regularly study the hormonal background.
Osteoporosis pills are also popular.
Active metabolites of vitamin D
Vitamin D can increase the absorption of calcium from the digestive system, and also reduces the leaching of this trace element from bone tissue. Indications for treatment are the presence of steroid and senile osteoporosis, and, in addition, calcium malabsorption syndrome. The most popular drugs in this groupthe following medicines are used:
- A drug called "Calcium-D3". In addition to the synthetic substitute for vitamin D, calcium is included in the composition of the presented medicinal product. Release this medicine in the form of tablets intended for chewing. This medicine has a very pleasant fruity taste.
- Medication "Ideos". This medical product regulates calcium metabolism, restoring bone tissue, and also promoting bone mineralization.
- Calcitriol medicine. This medication is often prescribed in the presence of a compression fracture of the spine, as this remedy relieves pain.
When implementing the course, experts recommend reducing the consumption of chicken eggs and butter in the diet, as hypercalcemia is likely to develop.
Estrogens as another category of drugs for women with osteoporosis
This category is for the treatment of women with postmenopausal osteoporosis. It is advisable to use estrogens as a means for preventive treatment. For women who are over sixty-five years old, these drugs are not prescribed because of their extremely low effectiveness at this age. Among the drugs of this pharmacological group, there are:
- Medication called "Estrofem". This drug can regulate a woman's menstrual cycle by preventing calcium from being leached out. The drug is produced in the form of tablets. The course of therapy is usually six months.
- Using "Livial". This medication is prescribed to women a year after the end of menstruation. According to statistics, the use of Levial at an early stage of postmenopause increases bone density in women by an average of four percent. In later periods, this figure increases by as much as five percent.
It is worth noting that when prescribing the above drugs, it is mandatory to be regularly examined by a gynecologist, since any hormonal medications can affect the mammary glands, and, in addition, myometrium.
And what are the best painkillers for osteoporosis to buy?
Non-opioid analgesics
In case of pain resulting from a compression fracture, people suffering from osteoporosis are prescribed non-opioid drugs that have analgesic and anti-inflammatory properties. True, these drugs do not have any effect on the underlying disease at all, and prolonged use of analgesics is fraught with the occurrence of diseases in the digestive system.
The treatment of osteoporosis with drugs should be comprehensive and timely. Features of therapy also consist in the use of fluoride preparations.
Fluorine preparations
These drugs are prescribed by doctors for osteoporosis in order to increase the mineralization of bone tissues. Specialists recommend treating with fluoride preparations in the presence of osteoporosis that has arisen against the background of the use of glucocorticosteroid drugs. Besides,a pronounced effect can be observed in the case of the use of fluorine-based drugs for the treatment of women in menopause.
The density of vertebral bones may increase by four or five percent a year. Fluorine preparations can be treated only after the diagnosis of osteoporosis has been confirmed. The most recommended among fluorine preparations are:
- A drug called Coreberon. The format of its release are tablets. Mostly elderly people suffering from senile osteoporosis are treated with Coreberon. This medicine has many side effects.
- Ossin medication. This drug is produced in the form of dragees and pills with different flavors. This drug is recommended not only for adult patients, but also for children. It is usually prescribed to maintain the level of fluoride in the human body. This medicine can be used for several years. The list of drugs - drugs for the treatment of osteoporosis is quite extensive.
Fluorides are very effective in the treatment of osteoporosis with spinal lesions. Adverse reactions often include joint pain along with digestive disorders.
Everyone wants to find the most effective cure for osteoporosis.
Calcitonin treatment
This category includes drugs that are also high in calcium. These medical devices fully prevent bone destruction. Doctorsit is recommended to treat with calcitonins steroid, senile or postmenopausal osteoporosis. The most convenient form of release is a nasal spray.
Treatment of osteoporosis with medication should only be carried out under medical supervision.
Drug "Sibacalcin"
The drug "Sibacalcin" contains synthetic calcitonin in its composition. This medication is produced in the form of a dry powder intended for injection, in ampoules of 0.25 or 0.5 milligrams. Dosing is selected individually. The medication "Sibacalcin" as a treatment is taken as a course for five months.
Another way to treat osteoporosis, what medicines?
Medication "Forteo"
This medication is also recommended by specialists for osteoporosis. This medicine is prescribed to treat a severe or advanced form of the disease. This medication is a synthetic thyroid hormone that increases bone density. A drug called Forteo is taken daily, the course of therapy directly depends on the result of the clinical examination.
It is worth noting that the drug in question can also be injected. The effect of calcitonins can be revealed very quickly, however, their beneficial compounds also rapidly leave the body. In addition, these drugs can be highly addictive with long-term use.
What else is on the osteoporosis drug list?
Strontium preparations
Strontium drugs form a separate category. They are produced in the form of suspensions in a sachet of 2 grams. In addition to strengthening bone tissue, such drugs also effectively affect cartilage tissue.
Such funds are usually used orally, one sachet per day, a couple of hours after a meal. To do this, one sachet is dissolved in 80 milliliters of water, and then stirred, and then drunk. Strontium-based drugs are recommended by doctors to be taken just before bedtime.
Among the adverse reactions are diseases of the digestive system. Additionally, the nervous system can also be affected. According to reviews, most often during therapy, headaches can occur along with general malaise. Such drugs are contraindicated for pregnant women, and, in addition, for patients suffering from diseases of the heart and blood vessels.
It is important to note that when using this drug for osteoporosis, you should limit your intake of dairy products in your diet, because they reduce the absorption of strontium.
Homeopathic remedies
Homeopathy has proven itself in the treatment of osteoporosis. But it should be borne in mind that such treatment requires a long time. Often, the first result from taking a homeopathic medicine appears years and months later.
Homeopathy is very effective in the treatment of diseases in the early stages and is suitable for the prevention of osteoporosis. Patients suffering from a severe or advanced form of the disease can be cured with these drugs only in combination withother medicines. According to many reviews, homeopathy can have a beneficial effect on the body only if the patient himself believes in this method of treatment.
How to choose the most effective medicine for osteoporosis, according to doctors?
Doctors advice
Doctors recommend giving preference to such a medicine as Bonviva and strontium preparations for osteoporosis. As the doctors write, these medicines are convenient to take and, in comparison with the Foroza medicine, they do not cause any side effects.
As for women, doctors are more likely to prescribe estrogen-based drugs for them. Experts also refer Zometa and Aklasta to the most effective drugs in the presence of osteoporosis.
It is better to read reviews about osteoporosis drugs in advance.
But all doctors unanimously declare that only the doctor should make the choice of this or that medication. Only a specialist can choose the optimal treatment solution for a particular patient.
And there are a lot of the most effective drugs for osteoporosis on today's pharmaceutical market. The main thing, according to doctors, is to take into account all the nuances and peculiarities of the he alth of a particular patient. And only then will it be possible to choose the most effective remedy for osteoporosis.
