Violation of the outflow of bile today occurs in many people, the reasons for this phenomenon can be different: liver pathology, high lithogenicity of bile, and so on. When choosing a choleretic drug, its pharmacodynamics must be taken into account. One of the effective means is "Berberine Bisulfate". The active ingredient is an alkaloid that is obtained from the root and leaves of barberry and other plants. In medicine, its sulfate s alt or bisulfate is used.
Characteristics and description of the drug
"Berberine bisulfate" is a choleretic drug produced in the form of yellow tablets. Each of which contains 0.005 grams of the active ingredient, which has the same name as the medicine itself. The pills are placed in a jar in the amount of fifty pieces.
Berberine bisulfate is a raw material of plant origin, it is obtained from the root and leaves of barberry. It has a pronounced choleretic and antispasmodic effect.
"Berberine bisulfate" found application for suchpathologies:
- Chronic hepatitis.
- Cholecystitis.
- Hepatocholecystitis.
- Cholelithiasis.
- Pathologies of the biliary tract.
- Chronic viral hepatitis.
- Peptic ulcer.
- Cholelithiasis.
- Dyskinesia of the gallbladder.
- Pathology of the liver in a chronic form.
Drug action
According to the instructions, "Berberine bisulfate" not only enhances the outflow of bile, but also lowers blood pressure, normalizes the activity of the heart, provokes uterine contractions, and has chemotherapeutic activity. Previously, this drug was widely used in the treatment of malaria and leishmaniasis.
"Berberine bisulfate" helps to accelerate the outflow of bile through the biliary tract, prevents the formation of gallstones, enhances the motor and digestive activity of the small intestine. Also, the drug stimulates labor, has a negative chronotropic and hypotensive effect.
The active substance irritates the receptors of the mucous epithelium of the duodenum, promotes the activation of the synthesis of cholecystokinin, which stimulates the outflow of bile, contraction of the biliary tract, and a decrease in their tone.
Thanks to the drug, bile production increases, its viscosity decreases.
"Berberine bisulfate": instructions for use
Doctors are instructing patients to take the study drug one or two pills three times a day. Tablets are taken before meals with a cleannon-carbonated water. The instruction contains the same data. But the course of therapy is determined on an individual basis. It can be from two to four weeks.
Use restrictions
The drug has some contraindications. These include:
- pregnancy and breastfeeding period;
- high susceptibility to drug ingredients.
The drug can be used in conjunction with other drugs. It does not affect the speed of psychomotor reactions, so it can be used while driving a car or other mechanisms.
Development of adverse reactions and overdose
Usually, the drug is well tolerated by patients, provided that the instructions and recommendations of the doctor are followed. In rare cases, the following adverse reactions may occur:
- reducing blood pressure;
- increased myometrial tone;
- allergic reactions;
- bradycardia.
In medical practice, no cases of overdose have been recorded. When using the medicine in large quantities, you need to rinse the stomach, take a sorbent and go to the clinic. Theoretically, if you take a large number of pills, you can develop nosebleeds and bradycardia.
If you experience any negative symptoms, it is recommended to consult a doctor.
How to store medicine
Store "Berberine bisulfate" is recommended in a dark, dry place. The air temperature should not exceed twenty-five degrees. Shelf life is threeyear from the date of issue. After the expiration of this period, the drug must be disposed of. Children should not have access to medicines.
Cost and purchase of medication
The drug is sold in many pharmacies in the country. To purchase it, you do not need a prescription from a doctor, but it is not recommended to self-medicate. The cost of the medicine is about one hundred and ten rubles.
Analogues
"Berberine bisulfate" is similar in pharmacological action to drugs such as:
- "Tanacehol" has a choleretic and antispasmodic effect, enhances the production and outflow of bile, normalizes its biochemical composition. The price of the drug is sixty rubles.
- Cholagogue collection - a choleretic agent of plant origin. In addition to choleretic, it has anti-inflammatory, antispasmodic and antibacterial effects. Its cost is about forty rubles.
- "Allochol" has a similar therapeutic effect. Also, the drug helps to eliminate flatulence. Its cost is from eight rubles.
Medic reviews
In medicine they talk about the beneficial properties of "Berberine Bisulfate". This substance has a positive effect on the activity of the cardiovascular system, contributing to the expansion of blood vessels and lowering blood pressure. Also, the drug normalizes the level of lipids, lowers the concentration of sugar in the blood.
This drug also has antioxidant andanti-inflammatory effect. It reduces pressure in the gallbladder, which helps to normalize the process of bile production, increases the synthesis of cholecystokinin.
In medicine, the drug is often used for pathologies of the biliary system. Doctors often prescribe the drug to their patients.
Patient testimonials
Reviews about the drug are mostly good. Many note its high efficiency and good tolerability. When using the drug for at least two weeks, there was an improvement in well-being. Some patients note that the drug helped to get rid of constipation, pain in the right hypochondrium, bitterness in the mouth.
There are a small number of people who talk about the development of adverse reactions in the form of itching of the skin, so they had to abandon this drug. But, most likely, this is an individual intolerance to its components, so before using the medicine, you need to study the instructions and consult a doctor.
Conclusion
"Berberine bisulfate" is a herbal drug that practically does not cause the development of adverse reactions and has a small list of contraindications. The medicine is usually well tolerated by patients, it effectively fights many problems.
Reviews of doctors and patients about the medicine are positive. They talk about the safety and effectiveness of the drug. It is prescribed in courses if indicated or once, when pain appears in the right hypochondrium.
