Hypertension and heart failure are very common diagnoses in today's world. Both elderly people and patients aged thirty years complain about them. Nowadays, these ailments are rejuvenated. Of course, there are more reasons for them in modern times. Stress, malnutrition, nervous tension, overwork have never had an excellent effect on good he alth.
Hypertension: effective interventions
Treatment of diseases of the circulatory system requires special attention. When the pressure jumps sharply, measures should be taken, by itself it will not stabilize. If this is not done, a person can get a myocardial infarction or stroke, the consequences of which can be very sad.
Hypertension and other diseases associated with pressure instability should be treated under the supervision of a doctor. Any amateur activity is inappropriate in this case.
Often, in order to bring the pressure back to normal, patients are prescribed a very expensive drug "Perindopril". Analogues, synonyms of thisMedicines are also not cheap medicines. However, knowing all the properties of the drug, you can still find a less expensive replacement for it in the modern pharmaceutical market.
Properties of the drug "Perindopril"
This is an effective remedy recommended by many experts. So, before looking for an analogue of "Perindopril", let's find out a little what it actually is.
This is a medicine from the group of ACE inhibitors that affect the restoration of muscle tone of blood vessels, due to which the pressure returns to normal. Pharmacological features boil down to the fact that perindopril, decomposing to perindopilate, reduces the content in the blood of elements that make the vessels inoperative. By expanding them, it is possible to increase the minute volume of blood and a tolerant mode of the heart is developed under such a load. A more detailed description is indicated in the instructions for the drug.
The drug is produced in the form of tablets containing the active substance perindopril in the amount of 4 mg, 5 mg, 8 mg, 10 mg.
The effect of the drug is noticeable an hour after taking it. After four hours, it reaches its maximum concentration and normalizes the pressure for the whole day. It does not affect conscious thinking, stimulates the brain, concentrates attention. Excreted from the body through the kidneys.
Reception is very simple, one tablet (the dose prescribed by the doctor) is drunk once a day before meals. If you take the medicine after a meal, it will act slowly.
Produced in Germany and Hungary. Pricepackaging of tablets varies from 500 to 600 rubles.
Drugs similar to "Perindopril" (analogues), instructions for use do not describe. Let's take a look at them below.
Indications for use
This drug is suitable for the treatment of type 1 and type 2 diabetics, which is why it is so popular.
The medicine "Perindopril" is prescribed for arterial hypertension, as well as chronic heart failure, is used to prevent recurrent heart attacks and strokes.
Contraindications
It is not recommended to prescribe this remedy to children, breastfeeding mothers, if there is an allergic reaction to perindopril, with renal diseases, with thrombocytopenia, leukopenia.
Possible side effects
This drug has a fairly wide list of side effects. Topical: dry cough, headache, insomnia, weakness with chest pain, convulsions, pruritus, bronchospasm, rhinitis, shortness of breath, muscle spasms, sexual disorders, depression, pneumonia, taste disturbance.
Medication "Prestarium A": perindopril + arginine
The composition of the medicine "Perindopril" includes: the active substance perindopril, erbumine s alt and auxiliary components - magnesium stearate, anhydrous colloidal silicon dioxide, a mixture of starch and lactose, acesulfame potassium.
Since the composition of the drug has been improved over the years, the drug Prestarium A, an analogue of Perindopril, appeared in pharmacies. So the differences between them are in the trade name of the drug and onecomponent. The drug "Prestarium A" instead of erbumine s alt includes arginine. Their effect on the human body is identical. Arginine only allowed the drug to be stored for three years longer.
But Prestarium A is more expensive than Perindopril, its price is 700 rubles per pack.
Many doctors advise patients to use in the treatment of hypertension a cheap analogue of Perindopril (hence, Prestarium A drugs) - Perinev tablets, which also include perindopril. Its cost varies from 200 to 300 rubles.
The group of analogues of the drug "Perindopril" includes such drugs as "Parnavel" (costs 300 rubles), "Hypernik" (300 rubles), "Piristar" (250-400 rubles), "Stopress" (360 rubles), "Arentopres" (400 rubles), "Parnavel" (280 rubles).
If you select substitutes for drugs such as Prestarium A, which contain arginine in addition to perindopril, the analogs listed above are also suitable for replacing them.
Cheap analogues of "Perindopril" that do not contain perindopril
If substitute medicines are identical in composition and effect on the patient's body, then other similar medicines may contain other components, but be characterized by the same effect in the treatment of heart failure and arterial hypertension.
For example, the drug "Lizinopril" is an analogue of "Perindopril", which contains an active substance similar in action to perindopril - lisinopril. italso a remedy from the group of ACE inhibitors.
The average cost of this analogue is 200 rubles. It is also available in the form of tablets. You can also find in pharmacies the medicine "Lizinopril" of Ukrainian production, German or Israeli. Buyers give preference to a product manufactured in Germany.
This remedy is ideal for obese and diabetic people who find it very difficult to find drugs to lower blood pressure, since many of them have a large list of side effects that are life-threatening for such patients.
The drug "Lizinopril" is widely used in the treatment of patients with pathological diseases of the heart and vascular system.
Of course, this remedy, along with its advantages, has its disadvantages, it can cause dizziness, nausea, dry cough, diarrhea.
The drug is contraindicated for use in diseases of the kidneys and liver, during pregnancy, breastfeeding, children under 18 years of age, with hereditary Quincke's edema, with intolerance to lisinopril and other components of the drug.
Choosing analogues for the drug "Perindopril", you can also stop at the drug "Enalapril". Its composition includes a substance similar in effect on the body of a patient with perindopril, enalapril maleate. This medicine is also an ACE inhibitor, therefore, lowers blood pressure and at the same time reduces the workload on the heart, preventing the complex consequences of hypertension.
In productionmedicine in Serbia, Macedonia. The drug has established itself in medical practice as reliable. Release form - tablets. The cost of one pack of pills is from 100 to 200 rubles.
It is necessary to pay attention to the fact that this drug is contraindicated in diabetes mellitus, pregnancy, renal and hepatic insufficiency, breastfeeding, and is not intended for the treatment of children.
May cause the following side effects: dizziness, asthenia, skin rash and itching, fatigue, drowsiness, anxiety, dry cough. Also, this drug can cause a sharp decrease in pressure, so its use should be accompanied by the supervision of the attending doctor, since the wrong dose can cause an overdose, and therefore worsen the patient's condition.
Many substitutes for the drug "Perindopril". Analogues of the drug can also be selected from the group of ACE inhibitors containing in their composition the active substance captopril, similar to perindopril. Such is the medicine "Captopril", which is applicable in the treatment of arterial hypertension, coronary heart disease and heart failure.
The drug is produced in Slovenia and Ukraine. The average cost of this medicine is 300 rubles.
Capotopril is not prescribed during pregnancy, breastfeeding, children under 18 years of age, with severe kidney and liver dysfunction, cardiogenic shock, in the presence of obstructions in the outflow of blood from the left ventricle of the heart, edemaQuincke.
This medicine may also cause side effects such as blurred vision, fatigue, headaches, thrombocytopenia, decreased appetite, stomatitis, pruritus, tachycardia, acidosis.
Before using cheap analogues of the drug "Perindopril", you should carefully study the instructions for them. Only the attending physician should prescribe them. Each of them has its own list of side effects and a list of contraindications that should not be underestimated.
Treatment of hypertension is not easy, each patient has his own tendency to tolerate one or another component of medicines, and it is not so easy to choose the right drug that will not cause discomfort during treatment.
The only way to select an individual therapeutic agent is through drug trials.
Noliprel, Co-Pyreneva: perindopril + indapamide
For many patients, it is not sufficient to normalize the pressure by taking only the medicine "Perindopril", the therapy is supplemented with several more effective means. To facilitate the work of doctors, pharmacists have created combined preparations with the basis of perindopril.
Thus, perindopril + indapamide analogs of perindopril with enhanced effects on the patient's body are composed of such as "Noriprel" and "Co-Pyreneva". Naturally, combined preparations are more expensive than pure perindopril. The cost of the drug "Noriprel" (perindopril + arginine + indapamide) is 800 rubles, the drug "Co-Pyreneva" (perindopril +erbumine + indapamide) – 650 rubles.
Cheaper, containing indapamide and perindopril, analogues-synonyms from the group of combined drugs: Prlamid tablets costing from 200 to 400 rubles, Co-Prenessa tablets - 400 rubles, Perindid - 300 rubles. The difference in price, as you can see, is palpable.
To the combination "perindopril plus indapamide" analogues can also be selected from the group of combined ACE inhibitors, which include other active substances. For example, Ampril Hd tablets (ramipril + hydrochlorothiazide) cost 400 rubles, and similar Euroramipril tablets cost 200 rubles.
The quality of analogues containing perindopril + indapamide is not particularly noted. A low price is not always a guarantee that the properties of original drugs will be preserved.
Drugs "Prestans", "Dalneva": perindopril + amlodipine
The experiments did not end with indapamide, because perindopril shows its effect very well in combination with amlodipine. Recently, the combined drugs Prestans (perindopril + arginine + amlodipine) have appeared, their cost is from 700 to 900 rubles, and Dalneva (perindopril + erbumine + amlodipine) - 500 rubles.
Containing perindopril + amlodipine analogues of a cheaper order can be selected from the group of substitutes, for example, Amlessa tablets, their price is 400 rubles, and from the group of combined ACE inhibitors that do not contain perindopril and amlodipine, for example, tablets "Akkupro" (quinapril) at a price of 200-300 rubles.
Which of the medicinalcombinations suitable for the patient, only the doctor knows, who has before his eyes a picture of the diagnosis after a thorough examination of the patient. If you need to choose cheaper analogues for the drug "Perindopril", then the attending physician also deals with this task, since only he can evaluate in practice the effectiveness of the action of a particular drug.
Reviews of doctors and patients about the drug "Perindopril"
The pharmaceutical market is overflowing with ACE inhibitors. Of these, there are a lot of drugs that replace the drug "Perindopril". Analogues and replacement, as you have already seen, can be identical both in composition and in effects on the body. But, despite such a variety of cheap substitutes for the drug in question, many patients still prefer to be treated with the original, as evidenced by their reviews.
Of course, if the patient cannot afford the original treatment, then there is a transition to cheap combined medicines, among which doctors have singled out more or less high-quality ones. Naturally, even among cheap drugs, doctors choose European-made medicines, among which there are practically no fakes.
The drug "Perindopril" in medical practice has proven to be reliable and effective, thanks to it, doctors today manage to restore the he alth of 80% of patients with arterial hypertension and heart failure, and also prevent complications in the form of myocardial infarction in 50% of them and stroke.
Having, of course, knowledge about what drugs can replace the drug"Perindopril" is much easier to navigate in a large list of ACE inhibitor medications. And when prescribing, it becomes easy to understand what the doctor specifically recommends for therapy - the original drug or its cheap analogue.
