The flu can be quite severe. For its treatment, antiviral agents are used, but in many cases it is not possible to avoid the addition of a secondary infection and the development of complications, such as meningitis, otitis, pneumonia. In 2013, a domestic pharmaceutical company released the Sovigripp vaccine, which is a worthy replacement for foreign drugs. It is actively used for free immunization of the Russian population. The vaccine contains substances that make up the surface shell of influenza viruses of different strains. Every year, the Sovigripp vaccine changes in its composition depending on the types of influenza, the spread of which is predicted for the next season. Basically, the disease develops as a result of the ingestion of viruses A and B. But the causative agent of the disease is constantly mutating, so there is a need to constantly change the composition of the vaccine, because it determines its effectiveness.
Composition, release form
Depending on the form in which the vaccine is produced, it may include a component of thiomersal with ethyl mercury, which acts as a preservative. Vials with such a product are used repeatedly, thanks to the preservative, fungal and bacterial contamination is excluded. If the drug is used in vials, each of which contains a separate dose of the vaccine, there is no preservative in the composition.
In the Sovigripp vaccine, the composition is represented by the following components:
- hemagglutinin of influenza viruses type B and subtypes A, which include H3N2 and H1N1;
- buffered phosphate saline;
- preservative;
- sovidone.
Phosphate-saline solution is made from potassium dihydrogen phosphate, sodium hydrogen phosphate and chloride, injection water. Thiomersal has been added to the vaccine solution with a preservative.
Pharmacological properties
The main difference between the vaccine and analogues is the presence of sovidone instead of polyoxidonium, it is used as an adjuvant and is an additive that enhances the body's immune response. Thanks to this substance, the following effects are achieved:
- protection of cell membranes;
- antioxidant action;
- formation of immunity to the negative effects of influenza viruses;
- detoxification.
"Sovigripp" instructions for use allows you to use it to form a high specific immunity against seasonal pathogensflu. The product is intended for intramuscular injection.
Indications
Immunization with the vaccine is indicated for people over the age of 18. It is necessary for the prevention of influenza. Most others need such a vaccine:
- persons over 60;
- students;
- military;
- people working in the police, trade, transport, catering, service, education and government;
- social workers;
- medical workers;
- people with immunodeficiency;
- people who have chronic diseases (somatic diseases, anemia, allergic diseases, diseases that affect the kidneys, heart, nervous and respiratory systems, diabetes mellitus) or often develop acute respiratory infections.
When using Sovigripp (vaccine), the instruction recommends paying attention to all the features of this drug. There are some restrictions for pregnant women. During this period, vaccination is allowed only in 2-3 trimesters, and only in cases where the benefits outweigh the possible risks. There is no negative effect on the fetus. Women who are pregnant are not at risk, but the effects of the flu on them can be serious, so it is worth getting vaccinated if possible.
Vaccination
Those who want to get vaccinated need to know what Sovigripp (vaccine) is. The instruction shows that immunization is carried out in early autumn. Thus it turns outprepare the body for a seasonal epidemic. The immune response occurs no more than two weeks after the administration of the drug. Sovigripp provides protection against influenza pathogens for a period of seven to nine months. Even if it has already become known about cases of the development of influenza, it still makes sense to get vaccinated. An anti-flu agent does not provide 100% protection against the disease, but significantly reduces the likelihood of influenza (by 75-90%).
Vaccination is carried out annually by introducing a single dose of a 0.5 ml solution. The intramuscular method is used to administer the vaccine. The vaccine is given in the shoulder (upper third). Before immunization, it is recommended to exclude contacts with people who have acute respiratory infections. You also need to dress warmly so as not to overcool. The same rules should be followed after the introduction of Sovigripp. Doctors' comments show that the vaccine can be wetted, experts recommend staying in the clinic for thirty minutes after vaccination. In the event that complications arise, he alth workers will quickly provide the necessary assistance.
Contraindications
Before vaccination with Sovigripp, contraindications to be aware of include the following cases:
- the likelihood of allergic manifestations caused by chicken protein or other components of the vaccine;
- period of exacerbation of chronic diseases;
- development of diseases in which the temperature rises;
- the occurrence of serious complications due to earlierconducted anti-influenza vaccination, such as severe swelling at the injection site, collapse, loss of consciousness, convulsive conditions, changes in body temperature with its increase to 40 ° C or more.
Side effects
Information about the occurrence of serious complications after vaccination with the Sovigripp vaccine does not contain doctors' reviews, because so far there have been no such cases. However, the possibility of such an outcome of immunization exists. The drug is highly purified, so it is usually well tolerated by the body. Sometimes some side effects may develop, most often systemic and local reactions appear, but they quickly disappear (within 1-2 days). Allergic reactions are very rare. Studies have shown that in 0.9-1% of cases, the injection site turned red in people, sometimes this area hurt a little, low-grade fever was present, but the negative manifestations quickly disappeared. Vaccine side effects include:
- runny nose, sore throat;
- headache;
- Quincke's edema, urticaria, rashes, anaphylaxis (may develop with hypersensitivity).
Special Instructions
"Sovigripp" instructions for use prohibits intravenous administration. Immediately before vaccination, a person should be examined by a doctor, thermometry is required. If the body temperature is more than 37 ºС, the vaccine is not administered. In rooms where immunization is carried out, there must be means intended forimplementation of anti-shock therapy. Yes, and after the introduction of Sovigripp, you should not drink alcohol for at least three days, because it negatively affects the process of producing immune antibodies, and helps to reduce the body's defenses. Drinking alcohol as a result of vaccination can cause a cold.
When opening the ampoules containing "Sovigripp" (vaccine), the instruction reflects the need to strictly follow the rules of antisepsis and asepsis. The same applies to the procedure for introducing the solution. The opened ampoule is unsuitable for further use.
Before using the vaccine, it is important to pay attention to the absence of changes in its physical properties, expiration date, labeling and integrity of the packaging, ampoules. Do not use product that has been improperly transported or stored.
Interaction with other tools
The vaccine is suitable for HIV-infected people, can be combined with other vaccinations (the only exception is the vaccine, which is directed against the development of tetanus), but in this case, its administration should be carried out in different areas. It is better to use a vaccine that is stored in clinics, as it is more likely to be properly stored in such institutions.
Sharing with other substances means "Sovigripp" (vaccine), the instruction recommends taking into account contraindications for each of the vaccines that are planned to be used. All drugs should be administered not only to different parts of the body, but alsodifferent syringes.
Cost of the drug, analogues
At "Sovigripp" the price is about 1700 rubles. (one dose). Other Russian vaccines can be purchased from analogues, such as Ultrix, AHC-vaccine. This group of vaccines includes Microflu, Grifor and Grippovac. As an analogue, you can use the drug of French production "Vaxigrip" or Swiss - "Inflexal V". From German vaccines, you can choose Fluarix or Agrippal. This country produces another remedy - "Begrivak". In the Netherlands, the Influvac vaccine is being manufactured. For influenza vaccination, you can choose Sovigripp or Grippol, a vaccine that is also an effective domestic product.
Reviews
Everyone decides for himself whether to get vaccinated against the flu, many people are against it. Although the instructions for Sovigripp indicate that it has not yet caused serious complications, some people do not feel well after its introduction. Some reviews contain information that after this vaccination, cases of colds have become more frequent. However, there are also enough positive reviews from people who tolerated vaccination well and did not notice any negative changes in the future. As the reviews of the Sovigripp vaccine show, the price turned out to be affordable for many.
