What is Dimexide for? Let's figure it out in this article.
The drug is a synthetic drug for external use, which has analgesic, antibacterial and anti-inflammatory effects. This medication is widely used in dermatological medical practice, and is also prescribed for muscle and joint pain.
Reviews about "Dimexide" abound.
Description
The main active ingredient of solutions of various concentrations for external use has a number of therapeutic effects:
- Anti-inflammatory effect - elimination of the severity of some manifestations of inflammatory processes, in particular, pain, tissue swelling and hyperemia (redness due to excessive blood supply).
- Local anesthetic effect - reduction of all types of sensitivity (mainly pain) due to blocking of nerve endings located infabrics.
- Antiseptic effect - suppression of various pathogenic (pathogenic) microorganisms - viruses, bacteria and fungi.
- Fibrinolytic effect - dissolution of fibrin plaque in the area of skin damage or inflammation, which prevents the regeneration (healing) of tissues.
Dimexide is used in cosmetology.
Through local application, the active substance quickly penetrates into the mucous membranes and under the skin into deep tissues. In addition, it significantly increases their permeability to other medicines, so solutions are in most cases used in combination with other medicines, after dissolving them in it.
What is the composition of Dimexide?
Composition and release form
The active substance of this medical product is dimethyl sulfoxide, auxiliary elements are nipagin (methyl parahydroxybenzoate), nipazole (propyl parahydroxybenzoate), sodium carboxymethylcellulose (sodium carmellose), purified water. The composition of "Dimexide" is described in detail in the instructions.
The drug is available in the form of concentrates for the preparation of solutions and gel for external use, in aluminum tubes, packed in cardboard boxes. There are no other forms of Dimexide release.
Pharmacological properties
Medication with anti-inflammatory and local analgesic effects. It has a moderate antiseptic property, has a fibrinolytic effect.
Dimethyl sulfoxide - the main substance, suppresses inflammatory tissue infiltration, helps stabilize the process of fibrin formation, increases microcirculation in tissues, stimulates erythrocyte aggregation, increases phagocyte activity, reduces neutrophil chemotaxis and the content of immune complexes circulating in the blood.
This active substance is able to penetrate through the layers of the skin, mucous membranes, bacterial cell walls (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability to drugs. This medicine is practically non-toxic.
Pharmacokinetics
According to the instructions for Dimexide, when the drug is applied, dimethyl sulfoxide is detected in the blood after about 7-16 minutes, and the maximum concentration of the substance is noted after 3-9 hours. As a rule, after 30-36 hours, dimethyl sulfoxide in the blood is no longer determined.
With external methods of using the drug, dimethyl sulfoxide penetrates into the joint cavities, binds to proteins in tissues and blood, does not accumulate.
This active substance is excreted from the body through urine unchanged and in the form of oxidation products - dimethyl sulfate and dimethyl sulfone, as well as in the form of dimethyl sulfide (reconstituted product) is excreted with exhaled air.
Indications for use
The drug "Dimexide" is prescribed in most cases as an element in the complex treatment of the therapy of the following pathologies:
- Various disorders in the musculoskeletal system: rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease), deforming osteoarthrosis (with damage to periarticular tissues), reactive synovitis.
- Erythema nodosum, limited scleroderma, discoid lupus erythematosus, athlete's foot, thrombophlebitis, keloid scars, eczema, alopecia, erysipelas.
- Sprains, bruises, traumatic infiltrates.
- Sciatica, trophic ulcers, furunculosis, purulent wounds, burns, acne.
What is Dimexide for? The medicine is used, as a rule, to prevent a possible inflammatory process due to damage to the epidermis, or to eliminate an existing pathological focus.
In the field of skin plastic surgery, the drug can be used to preserve homografts.
Indications for the use of "Dimexide" in gynecology
Medicine is prescribed when:
- cervical erosion;
- complications after surgery;
- thrush;
- colpite;
- cervicitis;
- vulvovaginitis;
- endometritis;
- adnexite;
- postpartum condition.
Contraindications
Pharmacological agent should not be used in the following pathological conditions:
- hypersensitivity;
- severe forms of liver or kidney failure;
- angina;
- atherosclerosis;
- cataract, glaucoma;
- stroke, myocardial infarction, coma;
- pregnancy and lactation period;
- Children under 12.
Prescribing a drug simultaneously with other drugs should be done with extreme caution, since it can increase not only the toxicity, but also the activity of some of them.
Method of using "Dimexide" and dosage
This medical product is applied on the skin, in the form of compresses, irrigations (washings) and applications. How to use the Dimexide solution for a compress?
In a solution of the drug of the required concentration, moisten gauze napkins and apply to the affected area for 20-30 minutes. On such a napkin, you can put a plastic film and cotton or linen fabric. The duration of the therapeutic course is 10-14 days.
In the treatment of trophic ulcers and erysipelas - apply a 30-50% solution of 50-100 ml several times a day.
For diffuse streptoderma and eczema, compresses with a 40-90% solution of the drug are used.
For local anesthesia with severe pain syndromes, a 25-50% solution is used in the form of 150 ml compresses.
Medical product "Dimexide" in the form of a gel is used externally. It should be applied in a layer on the affected areas 1-2 times a day. The duration of such treatment should be 7-14 days. A second course can be carried out no earlier than 10 days later.
How to use"Dimexide" in cosmetology?
For the skin of the face and other highly sensitive areas, it is recommended to use 10-20-30% solutions. You can make anti-wrinkle masks with this tool. For these purposes, Dimexide ointment and gel are usually used, a solution for such purposes is rarely used. For prevention, the procedure is carried out several times a month, and in case of skin problems for 10-14 days, 3 times a day.
In the field of skin plastic surgery, dressings with 10-20% solutions are used on transplanted skin homo- and autografts immediately after surgery and in the following days after it until the graft is permanently implanted. With a less concentrated solution of this medication, inflamed and purulent-necrotic cavities and foci are washed.
Features of the use of "Dimexide" in gynecology:
- Candles. As a means for complex treatment.
- Tampons. To do this, you will need sterile cotton wool, it is impregnated with a solution. These tampons are then inserted into the vagina. It is not recommended to use the remedy during menstruation, as there is a possibility of developing unwanted reactions.
- Compresses. Lidaza, novocaine, antibacterial agents, aloe can be additionally used. A clean cloth is wetted in the medicine, applied to the site of inflammation. The compress can cover diseased and he althy tissues.
- Electrophoresis. The drug can also be used in physiotherapy. The therapeutic effect is enhanced as the drug penetrates the tissues better.
What else does the instruction toDimexide?
Use in childhood
The drug is contraindicated for the treatment of children under 12 years of age, however, when patients reach this age, the drug is widely used not only to treat the above diseases, but also to eliminate an inflammatory cough. This symptom can be so debilitating that it requires the use of emergency measures to eliminate it. In addition, irritation of the respiratory tract and throat causes pain even during meals.
In this case, low-concentrated solutions of the drug "Dimexide" are used in the form of compresses.
A similar remedy for treating a child works as follows:
- stops inflammation in the lymphoid tissue by introducing a medicinal substance into the immediate focus;
- increases the properties of local immunity, stimulates the production of macrophages;
- actively promotes the introduction of medicinal substances that relieve spasms of the respiratory system and have a direct anti-inflammatory effect, without being introduced into the blood and absorbed in the body.
Medication has no warming effect.
For children, this compress is placed for 15-30 minutes, but no more. You can apply a gauze bandage not only on the throat area with pharyngitis or laryngitis, but also on the chest with inflammation of the lungs and bronchi.
Side effects
According to reviews of Dimexide, when using a medication in some casesthe following adverse reactions may occur:
- allergic - contact dermatitis, pruritic dermatitis, dry skin, erythematous rashes, mild burning, increased skin pigmentation, in rare cases - bronchospasm;
- digestive – nausea, gagging.
In case of an overdose of this pharmacological drug, dose-dependent negative effects may increase. In this case, the drug should be discontinued, the damaged area washed and the solution removed.
Special Instructions
Some patients may experience garlic odor in the air they breathe.
Before using the drug "Dimexide" it is necessary to test for tolerance to it. To do this, a little solution should be applied to the surface of the skin with a swab dipped in it. The occurrence of severe hyperemia and itching will indicate hypersensitivity.
When allergic symptoms appear during therapy with this drug, its use is stopped and histamine H1 receptor blockers are started.
Interaction with other medicines
The drug can enhance absorption and increase the effects of insulin, ethanol and other substances. This drug is compatible with antibacterial drugs, heparin, and NSAIDs.
In addition, the treatment with this agent increases the sensitivity of microorganisms to beta-lactam and aminoglycoside antibiotics, as well as to chloramphenicol, griseofulvin, rifampicin.
Analogues of the drug
Analogues of this medication for therapeutic effects are the following drugs:
- "Apizartron";
- "Larkbone";
- "Extra Hit";
- Capsicam;
- "Dolobene".
The composition of the absolute analogues of the drug "Dimexide" are:
- "Dimethyl sulfoxide";
- "Dimex";
- "Dimexide-Lugal";
- "Dimexide-JFF";
- Dimexide-FT.
Medication reviews
There are a lot of reviews about Dimexide, so we can conclude that this drug is widely used not only in the treatment of various infectious and inflammatory pathologies, but also for prophylactic purposes with a high probability of developing purulent infections of damaged areas of the body. This medicine is used not only at home, but also in hospitals and preventive departments.
The feedback from patients who used the Dimexide solution for compress reflects a large amount of information about its high efficiency. First of all, this applies to a variety of purulent lesions of the skin, resulting from injuries and bruises. At the same time, the patients noted that after the start of therapy with Dimexide in the form of washing a purulent wound, their condition improved significantly - the affected tissues healed faster, the manifestations of redness, swelling and inflammation of the skin decreased. Also, this medicine has proven itself in the treatment of burns - patients observed rapid healing of the burn surface,a significant decrease in the pain syndrome, which is especially pronounced in this pathology.
Leave reviews about "Dimexide" and people who used it to treat childhood diseases. They say that the drug effectively helps with a variety of pathologies of the throat and respiratory organs, which are of an inflammatory nature. These are pharyngitis, bronchitis, tracheitis, pneumonia, rhinitis, etc. At the same time, compresses with the drug in low concentrations were used, and the parents claim that the disease in the child passed much faster and easier.
