Chlorphenamine maleate is widely used in pharmacology today. This substance is part of a variety of drugs that are intended for the treatment of colds and respiratory diseases, as well as diseases of the upper respiratory tract. It is worth noting that this remedy is an effective antihistamine.
Chalorphenamine maleate: pharmacological properties
This substance is a well-known blocker that acts on histamine H1 receptors. Due to this mechanism of action, chlorphenamine maleate has excellent antihistamine as well as sedative properties. That is why this substance is used as a component of some combined drugs, as the severity of an allergic reaction is reduced.
This remedy acts on the capillaries, reducing the permeability of their walls. It also quickly narrows the lumen of blood vessels and relieves swelling. In addition, chlorphenamine maleate relieves hyperemia of the mucous membrane of the nasal passages, paranasal sinuses and nasopharynx, thereby facilitating breathing and general well-being of the patient. The same substance significantly reduces the amount of exudate andrelieves allergic symptoms such as itchy eyes and sneezing.
It is worth noting that chlorphenamine maleate begins to act approximately 20-30 minutes after entering the digestive system. The substance enters the bloodstream, where the corresponding blood protein binds to it. Thus, the transport of funds throughout the body is carried out. The duration of its effect is 4 to 4.5 hours.
Chlorphenamine maleate: indications for use
As already mentioned, this substance has strong antihistamine properties, therefore it is used to suppress an allergic reaction and eliminate its main symptoms. It is used to treat rhinorrhea, sinusitis, allergic rhinitis, rhinosinusopathy. In addition, it effectively relieves allergy symptoms in infectious and acute respiratory diseases.
The product is not used in its pure form, but is an integral component of some combined drugs. For example, it is part of such drugs as TheraFlu, Rinza, Antigrippin, Toff, Coldact, etc.
As for the dose of the drug, this indicator directly depends on the chosen drug.
Chlorphenamine maleate: contraindications and side effects
This substance has practically no contraindications. It is forbidden to take it only to patients who are hypersensitive to its components.
Adverse reactions also appear not too often. Since chlorphenamineMaleate has sedative properties, its use can cause drowsiness, weakness, and sometimes lack of coordination. As a rule, side effects disappear after a few days of use.
Rarely, a rash or dermatitis may occur. Some patients complain of dryness in the mouth and nose, which is associated with a decrease in the secretion of the mucous membrane of the upper respiratory tract. It is extremely rare that constipation, urination disorders, and double vision act as a side reaction. Sometimes taking the drug may be accompanied by anemia.
