"Pimafucin" - a modern antifungal drug to combat thrush. Safe. Rarely causes side effects. Treatment of thrush with "Pimafucin" can be carried out not only for women, but also for men, as well as for ladies who are expecting the birth of a child. And at all stages of pregnancy. The course lasts six days. But the patient's condition improves after the first use of the drug.
"Pimafucin": composition, release form
The drug "Pimafucin" is widely known in the medical field and is often used to treat fungal diseases. It has several release forms, these are:
- vaginal suppositories;
- topical cream;
- tablets, enteric pack.
Vaginal suppositories contain the active ingredient natamycin. In addition to it, the composition of the medicinal product includes the following additional components:
- ethyl alcohol;
- solid fat;
- sorbitan trioleate;
- polysorbate80;
- sodium bicarbonate;
- adipic acid.
Suppositories have a torpedo shape. They have a white-yellowish color with a slight brown tint. Packed in three pieces in an aluminum strip. Sold in a cardboard box of 3 or 6 candles, along with instructions for use. The shelf life of vaginal suppositories is two years. Suppositories are stored at a temperature not exceeding 25 ° C.
The cream, like suppositories, contains the active ingredient natamycin. In addition to it, the composition contains:
- wax;
- sodium lauryl sulfate;
- decyloleate;
- propyl parahydroxybenzoate;
- propylene glycol;
- methyl parahydroxybenzoate;
- cetostearyl alcohol;
- purified water.
The cream has a dense creamy consistency and is colored white. Packed in a tube of 30 g and enclosed in a cardboard box with instructions. The shelf life of the drug is four years.
The tablets are enteric-coated. Contains the active ingredient natamycin. Additional components of the drug are: potato starch, povidone, magnesium stearate, lactose monohydrate. The shell consists of cellacephate, sucrose, triacetin, calcium carbonate, methyl parahydroxybenzoate. The composition of the shell also includes kaolin, acacia gum, white beeswax, titanium dioxide, gelatin and talc. The tablets are round in shape. Coated in white. Enclosed in a brown glass bottle of 20 pieces, which is enclosed incarton box with instructions. Tablets have a shelf life of four years.
Side effects from Pimafucin are rare. But in order to avoid negative phenomena at all, one should take into account contraindications and follow the scheme for using the drug prescribed by the doctor.
Pharmacology of a drug
The active ingredient natamycin is a polyene antibiotic. Belongs to the group of macrolides. Has antifungal properties. Has a wide spectrum of activity. It connects the sterols of fungal cells, thereby violating their integrity. This leads to the destruction of pathogenic microorganisms.
Many yeasts are sensitive to natamycin. Among them are Candida albicans, T.vaginalis, Aspergillus, Penicillium, Cephalosporium. Dermatophytes are less sensitive to the drug.
Yeasts do not develop resistance to natamycin even with prolonged use of the drug.
With local and external use, the drug is not absorbed into the blood if the skin is not damaged and remains intact. This also applies to the mucous membranes.
The tablet form of the drug is equipped with an enteric coating and acts only in the intestinal lumen. The active substance is not absorbed from the gastrointestinal apparatus and does not have a systemic effect. Therefore, Pimafucin causes side effects in rare cases.
Indications for use
Is it possible to use "Pimafucin" whenpregnancy? Yes, this is one of those remedies that are allowed to be used not only during the period of expectation of a child, but also when breastfeeding a baby.
Each form of release of "Pimafucin" has its own purpose. The cream is indicated for fungal diseases caused by Candida fungi, which appear on the skin and mucous membranes. Effective for balanoposthitis, vulvovaginitis, vulvitis. It gives a good result in the treatment of candidiasis of the dermis and nail plate. The cream is used for otitis externa, the appearance of which was caused by fungi or is accompanied by candidiasis. The medicine is used for ringworm.
Pimafucin vaginal suppositories are indicated for vulvovaginitis, vaginitis and vulvitis. The appearance of which was influenced by Candida mushrooms.
Pimafucin tablets are prescribed for intestinal candidiasis. With candidiasis of acute pseudomembranous and acute atrophic type, complicated by immune deficiency and cachexia. The drug is used for candidiasis, which arose due to treatment with antibiotics, cytostatics and corticosteroids.
Pills are indicated for the sanitation of the intestinal reservoir with Candida fungi, for candidiasis of the dermis and mucous membranes. This includes vulvitis, vulvovaginitis, and candidal vaginitis.
Contraindications
About how to apply "Pimafucin", the instruction tells in detail. She also warns that the drug is not used if there is hypersensitivity to the substances that make up its composition.
Pimafucin is also prescribed for pregnant women. There is no evidence of negativeimpact on fetal development.
How to take the drug in tablets and how to use the cream and suppositories?
Pimafucin tablets should be taken orally. Regardless of food. If there is intestinal candidiasis, then it is recommended to drink a tablet 4 times a day. Children are given one pill twice a day.
With vaginitis of fungal origin in a severe stage of development, treatment with tablets is combined with the use of local remedies, for example, with Pimafucin cream or suppositories. For sanitation of the intestine affected by candidiasis, only pills are taken. "Pimafucin" is taken according to the instructions, 1 tablet up to four times a day.
The duration of treatment in each case is individual. After the negative symptoms have disappeared, the therapy is continued for a couple more days.
Cream "Pimafucin" in the treatment of balanoposthitis, vulvovaginitis and vulvitis is applied to the affected area from one to two times a day. With a complex course of diseases such as vulvovaginitis and vulvitis caused by the fungus Candida albicans, Pimafucin tablets or vaginal suppositories are additionally prescribed.
In ringworm (this includes fungal infections of the skin and nail plate, as well as diaper rash in children), an external agent is applied to the affected area up to four times a day.
If there is mycosis of the ear canal, then the area affected by the fungus is treated with cream up to four times a day. First, the ear is cleaned of impurities. After the cleansing procedure, the turunda is twisted from cotton wool,cotton or wool, generously smeared with cream and placed in the ear canal. The duration of therapy is determined by the doctor.
Vaginal suppositories for such diagnoses as vulvovaginitis, vulvitis and vaginitis, are administered one at a time at night, for 3-6 days. The introduction of suppositories is carried out in the supine position, trying to place the suppository as deep as possible. If the diseases provoked by Candida albicans continue to progress, then Pimafucin tablets are prescribed for oral administration. The drug is recommended to drink one tablet four times a day, to sanitize the focus of fungal infection in the intestinal environment. Treatment is carried out for 10-20 days.
With a fungal infection of the genital organs in a man, Pimafucin cream is used. The therapeutic course is prescribed by the doctor in each case individually. After the disappearance of negative symptoms, therapy is continued for several more days.
Side effects
Pimafucin tablets cause side effects from the gastrointestinal tract. They manifest as nausea and diarrhea. Usually occur on the first day of taking the drug. Do not require discontinuation of treatment. With the passage of therapy, negative symptoms disappear on their own. If other side effects appear, stop taking the medication and seek medical help.
When using suppositories and Pimafucin ointment, side effects are quite rare. Usually this is a slight irritation of the mucous membranes or the skin. Itching and burning in the application area.
Special Instructions
Which is better - Pimafucin or other antifungal drugs such as Clotrimazole, Zalain, Flucostat? This should be decided by the doctor. After all, only he, based on the picture of the disease, can prescribe the right treatment.
When taking Pimafucin tablets to patients with Lapp lactase deficiency, galactose intolerance, malabsorption of glucose-galactose nature and sucrase-isom altase deficiency, it should be taken into account that the composition of the pills includes sucrose and lactose monohydrate. If there is at least one of the above pathologies, then you should consult a doctor for advice.
"Pimafucin" in the form of tablets should not be given to infants. This prescription may cause difficulty in swallowing the drug.
Vaginal suppositories melt quickly under the influence of body heat. In doing so, they create a foamy mass. This ensures their uniform distribution over the vaginal mucosa. If the disease has become chronic or recurs, then in addition to the suppositories, a cream or tablets are prescribed.
Cetyl alcohol contained in candles can cause a slight burning sensation in the genital area. This feature should be paid attention to people who are hypersensitive to this substance. For the period of menstruation, therapy with vaginal suppositories is stopped. When treating with candles, patients are allowed to have a full sexual life.
When a fungal disease is detected in one of the partnerscandidiasis nature, the second partner should also undergo an examination. If a candidal lesion is detected, a full therapeutic course should be completed with one of the Pimafucin medications. Barrier contraceptives should be used during treatment.
Data on overdose of "Pimafucin" is not available. The drugs do not interact with other medications.
"Pimafucin" does not affect the ability to drive a car and concentration, reaction speed, which is used when working with complex mechanisms.
"Pimafucin": analogues
The instruction warns that you should consult a specialist before using the drug. If for some reason the drug did not fit, then analogues can replace it. These include:
- "Primafungin". Direct analogue of the drug. Contains natamycin. Produced in the form of candles. It costs about 150-300 rubles.
- Ecofucin. Direct analogue in the form of candles. The active ingredient in its composition is natamycin. The price ranges from 160 to 380 rubles.
- "Fluconazole". Produced in tablets. It is similar in its action, but has a different composition. Cost - from 14 rubles.
- "Nystatin". A drug with a different composition, but with similar properties. Its price ranges from 50 to 140 rubles.
- "Itraconazole". Produced in tablets. It has a different composition, but a similar effect. Its cost starts from 260 rubles.
Analogues to the cream "Pimafucin" can serve as ointment "Nystatin", gelMiconazole and Clotrimazole cream.
What is better - "Pimafucin" or its substitutes? This question is difficult to answer. After all, each medicine is good in its own way. Has its advantages and disadvantages. When prescribing, one should rely on the severity of the pathology, the condition and age of the patient, and the material possibilities of the patient. All this is taken into account by the doctor when prescribing the drug.
Cost
"Pimafucin" causes side effects in rare cases and is well tolerated by patients. The cost of 20 tablets fluctuates around 500 rubles, the price of a cream in a tube of 30 g is 300 rubles. Three candles can be purchased for 250 rubles. Pimafucin preparations are sold in pharmacies and dispensed without a doctor's prescription.
Patient testimonials
Treatment with "Pimafucin" gives an excellent result, which is confirmed by numerous reviews of patients. People say that pills and suppositories effectively fight thrush. Eliminate the symptoms of candidiasis quickly. A particularly good effect appeared when suppositories, tablets and cream were used in combination. In this case, women got rid of thrush for a long period. Reviews of the ladies claim that it is important that the sexual partner also undergoes treatment. Otherwise, re-infection will occur and the disease will progress.
Some patients claim that "Pimafucin" is good only at the initial stage of the disease, and with recurrent thrush this medicine does not always help.
Of the negative aspects, patients noted the side effects that the medicine caused. Among them: abdominal pain, nausea, system disorderdigestion. Some patients say that the course of treatment with Pimafucin is expensive, especially if all forms of the drug are used simultaneously. According to them, this medication does not always give a good result in the treatment of a fungal infection.
