Pregnancy planning for some is limited to a medical examination and taking the necessary vitamins, others face a number of difficulties and difficulties. In some cases, this is caused by a decrease in ovulatory function in a woman or the presence of diseases of the pelvic organs, often the ovaries.
What is ovulation
To understand how and how to stimulate ovulation, you need to be able to determine its onset, to know the definition of this term. This is the name of the exit from the ovary of the egg into the cavity of the fallopian tube as a result of the rupture of the dominant follicle. It happens that a woman goes through an anovulatory cycle, which can be repeated for several months in a row. This is due to the fact that the dominant follicle does not mature in the ovaries and the egg is not released for its subsequent fertilization into the cavity of the fallopian tube. According to studies, about 25% of women face this problem.
Before going to the doctor, a woman can determine a malfunction in the body at home. For thisit is necessary to observe how the menstrual cycle goes. For example, some note that the interval between bleeding has increased, and the discharge has become more scarce. These are indirect signs of a hormonal imbalance and possible problems associated with the onset of ovulation.
Some experienced scheduling women measure their basal temperature by plotting it on a chart. Conducting observations over several cycles allows us to speak about the reliability of the data obtained. Do not exclude changes in the body of a woman, which can be traced by secretions. The fact of ovulation is manifested in the form of transparent, viscous secretions similar to egg white.
However, the most obvious way is to conduct folliculometry, which allows you to visually determine the number of mature follicles, as well as the presence of a dominant one among them. This study is carried out for several days before the start of the expected ovulation. It also allows you to establish its absence.
Indications for stimulation
The main indications that are associated with the need to stimulate ovulation is the absence of pregnancy in a couple who have been trying to conceive for a year, but all attempts are unsuccessful. If their age exceeds 35 years, then this period is reduced to six months. Only a qualified doctor can determine the need for additional assistance to the female body. Therefore, the indications for use and the need to take any drugs are judged after a series of studies and analyzes.
To achievea positive result is prescribed folliculometry, and also check the patency of the fallopian tubes. If there are adhesions in the pipes, then the effect of stimulation will be zero. As for the growth and development of the dominant follicle, ultrasound can determine how this process proceeds in the ovaries.
In the case of diagnosing problems associated with the onset of ovulation, a couple can be offered several solutions, the last of which is the IVF program. This procedure involves not only the use of donor material, but also your own eggs, which will later be fertilized. Accordingly, it is necessary to prepare the body for the dominant follicle to mature in the ovary. Before starting the manipulations, the doctor explains how to stimulate ovulation during IVF, what vitamins and medications you need to take. They will help the body if it cannot cope on its own.
Types of drugs for stimulation
Before you stimulate ovulation, you need to find out what drugs are prescribed in a particular case. When it comes to problems with the release of an egg to stimulate the rupture of the follicle, hormonal drugs such as Horagon, Ovitrel, Prophase, Pregnil are prescribed. Follicle-stimulating hormones (FSH) include Puregon and Gonal. They have a similar structure to the natural hormone in terms of the production of the female body. Drugs that contribute to the suppression of estrogen increase the level of FSH - "Duphaston", "Clomid", "Klostilbegit", "Serofen".
It is noteworthy that the processstimulation of the ovaries should not be resorted to too often, this leads to their exhaustion. The attending physician can say exactly how many times in a row you can stimulate ovulation, because he knows the medical history and monitors the patient's he alth. It also requires constant medical monitoring of the condition of the ovaries.
When taking hormonal drugs, some women report the onset of side effects in the form of insomnia, pain in the lumbar region and lower abdomen, sweating, increased anxiety, and weight gain. However, in most cases, reviews of stimulation converge on the fact that women do not experience severe discomfort while taking medications.
Hormonal drugs for stimulation
When the question arises of how to stimulate ovulation, doctors offer one of the leading remedies in medical practice - Clostilbegit. It refers to antiestrogen drugs, which is available in the form of tablets. It is very specific in terms of action: it binds the estrogen receptors of the pituitary and ovaries. If an insufficient amount of estrogens is observed in the female body, then this drug contributes to a slight increase in it. Otherwise, when there is an excess of this hormone, Clostilbegit acts as an antiestrogenic agent.
Before starting the reception, many are interested in the reviews and results of Klostilbegit. In most cases, it has a positive effect, in the annotation to the drug it is also noted that its administration contributes to the onset of multiple pregnancy. For some planning couples, thisthe fact becomes very expected and positive. Therefore, it can be recommended to those who are thinking about how to stimulate ovulation to conceive twins.
It is worth remembering that there are contraindications that must be studied before taking. These include:
- Hypofunction or pituitary tumors.
- Ovarian cysts (except PCOS syndrome (polycystic).
- Failures in the work of the adrenal glands and thyroid gland.
- Lactose intolerance.
- Renal or liver failure.
- Endometriosis.
This list is not final, but contains the main diseases that prevent the reception of "Klostilbegit". The duration of admission is 5 days, before the onset of the expected ovulation. If the drug did not have the desired result, then its administration is stopped for 3 cycles and only then the course is repeated again.
Based on the opinion of doctors, it is worth noting that in most cases these are positive reviews. The results of "Klostilbegit" among patients and are estimated by high figures. Many couples have become happy parents thanks to this drug.
Vitamin Therapy
Fans of traditional medicine know how and how to stimulate ovulation, what proportions of herbs should be added as raw materials for preparing decoctions and infusions. One of the most popular herbs that stimulate the production of progesterone in the female body is the upland uterus. If the reason for stimulation is its insufficient amount, then it is worth consulting with a doctor regarding the possibilityinclusion in the diet of a decoction of this plant.
Not to do in this case without taking vitamins that stimulate ovulation. They enhance the functions of the body, in particular folic acid, potassium iodide, iron and vitamins D, E, A. It is recommended to continue taking them after pregnancy in order to properly lay the internal organs of the fetus, its nervous system and normal development. It is recommended to start taking vitamins from the first day of the cycle and not to stop them with the onset of pregnancy.
Some forums are full of various promotional offers that supposedly can replace the effect of drugs. You should not delay contacting a doctor and stay in the hope that they will replace proper treatment. The use of vitamins is recommended as a concomitant therapy, and not a substitute.
Injections to improve ovulation
When it comes to what are effective injections that stimulate ovulation, doctors answer: "HCG" (chorionic gonadotropin) and "Gonal". The first is also prescribed in combination with a drug such as Clostilbegit. Together, they contribute to the production of hormones necessary for the onset of ovulation and prevent the development of a follicular cyst. HCG injections contribute to the growth of the dominant follicle, which in the future will allow ovulation to occur. If there is a lack of progesterone production in the female body, then this often becomes the cause of an unsuccessful pregnancy or the development of infertility.
HCG injections are prescribed in preparation for IVF,when additional stimulation of ovulation is needed. As a rule, a dosage of 5000 units. is sufficient to achieve the desired result. Injections are carried out intramuscularly, while the most optimal place for inserting a needle is the abdomen. This is explained by the fact that in this area the injection is felt less painful than if it is given in the gluteal muscle. The time for the introduction of hCG as an injection is determined jointly with the doctor after ultrasound monitoring.
"Gonal" is considered a less harmful hormonal drug, easier to tolerate and prevents the formation of cysts. This drug is used in the first week of the menstrual cycle, and the duration is determined based on the results of the tests, which reflect the level of estrogen. If there is no positive effect in the current month, the next dosage is doubled.
Gonal is produced in the form of a syringe-pen, which contains the required amount of the drug. Judging by the user reviews, no painful symptoms are felt during the injection. Clear instructions for use for "Gonal F" allows you to independently carry out the procedure at home. It is important to comply with all requirements for the safe and proper storage of the pen, to control the dosage administered. The use of funds in the form of a powder should be carried out under the supervision of the attending physician. This is due to the fact that the dose of follitropin depends on the solution for the preparation of the injection.
According to the instructions for use of "Gonal F", the likelihood of multiple pregnancy is high. However, judging by the reviews, many couples who are already desperate to conceive a baby will be happy if they manage to get pregnant with twins or triplets at once.
Dufaston
Many years of experience in using this drug is no longer a discovery for anyone, as well as its positive properties. Therefore, questions such as whether Duphaston stimulates ovulation are being asked less and less. Most women who have experienced problems with conception and menstrual irregularities speak of Duphaston as a remedy that causes almost no side effects compared to its counterpart, Utrozhestan. It restores the cycle, contributes to the normalization of the luteal phase.
The active ingredient dydrogesterone does not have a negative effect on the blood coagulation process, liver function, carbohydrate metabolism. The duration of taking "Dufaston" as a drug that promotes the onset of ovulation is from 3 to 6 months. The timing of admission is determined by the doctor, in particular, in case of insufficiency of the second phase - from 14 to 25 days of the menstrual cycle. It is advisable not to stop taking the drug without consulting a doctor.
The main indication for use is hormone replacement therapy. The drug allows you to save the onset of pregnancy due to the fact that it stimulates the natural production of progesterone. Reviews of women who took the drug during planning claim that it is well tolerated, there are no changes in mood, sleep disturbances, which is more common in other hormonaldrugs.
Letrozole
One of those drugs that can be used an unlimited number of times. Unlike "Klostilbegit", which is used no more than 6 times during a lifetime, "Letrozole" is allowed to be used as much as needed. Naturally, it is necessary to coordinate its reception with the attending physician. Most women who use this drug live abroad. This is explained by the fact that abroad it is very popular and effective. It is noted that pregnancy occurs already in the first cycle of the drug.
As stated in the instructions for "Letrozole", it helps to reduce the level of estradiol. This leads to the fact that the pituitary gland produces an increased amount of LH (luteinizing hormone) and FSH, which favorably affects the onset of ovulation. With the combined use of "Letrozole" with injections of "hCG", a better state of the endometrium is noted. This has a positive effect on the likelihood of pregnancy and maintenance.
While taking this drug, women note the absence of unpleasant side effects that accompany them while using other hormonal drugs. In particular, weight, mood do not change, there are no hot flashes, sweating, dryness in the vagina. However, it is also noted that this tool is much more expensive than its counterparts.
The instructions for "Letrozole" say that it is used primarily as an anticancer drug. This is due to the fact that it is in the processtesting, and the effect on the ovulation process is still under study. Therefore, it is not recommended to use it as a means for self-medication.
Puregon
Contains follitropin beta, which is a follicle-stimulating hormone called Puregon. The instructions for use say that its use is indicated to stimulate superovulation. The drug is effective in terms of preparation for the IVF and ICSI procedures, as well as before intrauterine insemination, during the embryo transfer procedure.
Those who have experienced problems with conception know firsthand what stimulates ovulation with polycystic ovaries. This drug is also indicated for restoring the anovulatory cycle, as well as in the absence of a positive therapeutic effect as a result of taking Clomiphene.
On sale the drug is found in the form of a solution for injection. It is administered subcutaneously or intramuscularly, depending on the dosage. According to the instructions for use for Puregon, it can be 100, 150, 200 IU (the drug can be administered both intramuscularly and subcutaneously), 300, 600 or 900 IU - only subcutaneously.
In the process of therapy, constant monitoring of how the ovaries react to this drug is necessary. According to reviews, positive results from the appointment of "Puregon" during IVF can occur as a result of its use over several cycles. If we are talking about a period of more than 4 months, then there is a decrease in its effectiveness. As soon as the results of the ultrasound examinationthere is a growth of the dominant follicle, injections of "hCG" are added to this drug, which helps to retain the egg in the uterine cavity and the development of pregnancy. This measure is not mandatory if there is an increased growth of several follicles. When a couple does not want a multiple pregnancy, the use of hCG is excluded.
The drug, which is sold in cartridges, is convenient to use, as a woman can independently carry out the procedure at home. In order to eliminate the risk of developing fatty atrophy, it is recommended to alternate the injection site. It is advisable to carry out the first injection in a medical facility, together with a doctor.
Efficiency reviews
Before considering the need for hormone therapy, it is important to find out which hormone stimulates ovulation and whether there are deficiencies in its production by the woman's body in vivo. Reviews of doctors agree that independent attempts to identify and cure certain abnormalities in the reproductive system lead to a deterioration in the overall picture of the disease. Alternative methods of treatment do not always have the desired effect, and the use of drugs on the recommendation increases the timing of the onset of normal ovulation.
Only an experienced specialist can tell you how to stimulate ovulation at home. Reviews of the successful use of this or that drug are based on the fact that the woman had previously undergone a complete study, and this remedy was selected for her by the attending physician based on the characteristics of the conditionher he alth. Therefore, it is extremely important to seriously approach the issue of planning for those couples who are faced with the problem of conception.
Even if you find out which pills stimulate ovulation, they may not have the desired effect. The secret here lies in the fact that this or that concomitant hormonal treatment is aimed at solving a specific problem. As it turned out from what was written above, the reason for stimulating ovulation may lie not only in the fact that a woman has a lack of a hormone, but also in the fact that a mature follicle simply cannot be released. Drugs that contain components that suppress the activity of certain hormones that prevent the onset of ovulation can also help him in this.
Positive reviews in general are based on the fact that the treatment regimen was chosen correctly and took into account certain characteristics of the female body. Despite the fact that medicine does not stand still, some long-known drugs, such as Dufaston, to this day help to cope with the problems of conception and pregnancy, contribute to the normalization of the ovulatory cycle.
In any case, the effectiveness of treatment does not depend only on taking medications, it is important to follow all the doctor's prescriptions, adhere to proper nutrition and avoid excessive stress, nervous strain. The female hormonal system is extremely sensitive to any changes. Therefore, the likelihood of ovulation directly depends on how seriously the lady approaches this issue. It is important that her partner also provides her with all possible assistance in this,contributed to the preservation of harmony and peace in relations, provided support.
