In the article, we will consider the instructions for use and reviews for the drug "Klion-D 100".
Trichomonas and fungal infections appear in women very often. The reasons for this can be very different, ranging from weakened immunity and heredity, ending with casual and unprotected intimate relationships. Among the many drugs, one of the best is Klion-D 100. This drug locally fights infections, producing a medicinal effect. In the article, we will get acquainted with the instructions for using these vaginal suppositories, in addition, we will find out what analogues it has, and in at the end we will find out the opinion of patients about this drug, who used it for treatment.
Description of the drug
According to the instructions for "Klion-D 100", the presented vaginal suppositories are intended for the treatment of a mixed infection caused mainly by a yeast-like fungus in combination with Trichomonas. The course of treatment, as a rule, is about ten days,after which it is required to confirm the absence of a pathogenic agent by conducting a control test, which must be performed during the next three menstrual cycles. It is worth noting that this tool has some contraindications for use. For example, these suppositories cannot be used in the first trimester of gestation, and in addition, while breastfeeding.
Pharmacological action
The antifungal effect of the drug "Klion-D 100" is made possible thanks to two powerful components: miconazole and metronidazole. The first active ingredient of vaginal suppositories fights the disease by affecting the cell membranes of pathogenic microorganisms.
These microorganisms begin to weaken and soon die. The substance miconazole helps to get rid of annoying itching, which is often accompanied by ailments of a fungal nature.
Suppositories "Klion-D 100" act as an antiprotozoal and antibacterial agent. The active substances penetrate the DNA of microbes, blocking the processes of cell division. Due to this, the pathogen stops growth and reproduction.
Since the absorption of this drug is very high, the active ingredients of the drug penetrate into the mother's milk, spinal cord and placenta. This drug is excreted in the urine. As a result, urine may turn brown.
Composition and format of release
As the instructions indicate, "Klion-D 100" is available in the form of vaginalcandles. Each suppository contains 100 milligrams of metronidazole and miconazole. In addition to these components, sodium lauryl sulfate is additionally used along with magnesium stearate, povidone, colloidal anhydrous silicon and sodium bicarbonate. In addition, the composition also includes crospovidone, tartaric acid and lactose monohydrate.
Vaginal suppositories are white in color and almond-shaped with a rough surface. Candles are packed ten pieces in foil blisters. The composition of this medicine is aimed at destroying the focus of fungal infection in a short time, and in addition, actively resisting it.
In what cases is the use of "Kliona-D 100" shown?
Indications for use
The presented drug is used to treat female infections that originated against the background of infection with Trichomonas and Candida. That is, this medicine is used for thrush and vaginitis of a different nature.
When Pregnant
During lactation and during the first three months of gestation, the use of this drug is strictly contraindicated. This is explained primarily by the fact that it can penetrate the placental barrier and into breast milk. Starting from the second trimester, this remedy in the form of vaginal suppositories is used only as directed by the doctor in case of emergency.
When menstruation
There is no categorical ban on the use of these vaginal suppositories during menstruation as such. But during the release of the blood mass, some portion of the dissolved candle may simply come out. Eventuallyit turns out that, for example, only half the dosage will have an effect, which, of course, is not enough for treatment. In this regard, it is better to postpone the therapy with the presented drug during this period of the cycle, since there will be no effect when using suppositories.
Contraindications
These vaginal suppositories should be used with caution by women who have an individual intolerance to at least one ingredient that makes up the medicine. A contraindication for vaginal suppositories are also the first twelve weeks of pregnancy, and in addition, the lactation period. It is also forbidden to combine this medicine with alcoholic beverages or medical products based on disulfamiram.
Like any other medication, these vaginal suppositories can cause some side effects in patients. Next, find out what adverse reactions should be feared when using them for treatment.
Side effects
Some women leave complaints that they have orange discharge after this medication, the patients consider them an adverse reaction. But in fact, the discharge is completely different depending on the nature of the inflammatory process that occurs in the vagina. Orange color indicates severe inflammation of the mucous tissue. Such a specific color occurs due to blood impurities from the affected area. This phenomenon is considered normal and does not require an immediate interruption of vaginal suppository treatment.
Also, according to the instructions andreviews, "Klion-D 100" can cause a number of adverse reactions. For example, agranulocytosis, neutropenia, thrombocytopenia or leukopenia may develop. The immune system may respond with anaphylactic shock. Among other things, adverse reactions such as decreased appetite may be observed along with the appearance of mental disturbances, hallucinations, confusion and bad mood.
As for the reaction of the nervous system, it can react with headache, convulsions, drowsiness, encephalopathy, dizziness, ataxia or taste disorder. There may be a short-term visual impairment along with blurring of the image and a decrease in its sharpness. Sometimes patients have a violation of color perception, as well as optic neuropathy with neuritis.
The digestive system may experience nausea, vomiting, diarrhea, dry mouth, inflammation of the mucous membranes, stomatitis or anorexia when taking this medicine. In laboratory indicators, darkening of urine may be recorded.
Drug Interactions
What else does the instruction for the use of "Kliona-D 100" tell us? This drug can be combined with antibiotics from the category of sulfonamides.
This medical product interacts very badly with disulfiramine-based drugs. Their simultaneous use contributes to the emergence of confusion.
This drug greatly enhances the effect of anticoagulants, therefore such drugs should only be prescribedspecialists.
Vaginal suppositories "Klion-D 100" can increase the concentration of lithium in the blood. For this reason, it is necessary to either adjust the dosage or reduce it.
Alcohol Compatibility
Alcoholic drinks with this drug are combined very poorly. Their simultaneous use can provoke the development of flushing, abdominal pain, vomiting, nausea or headache.
Dose and overdose
As a rule, no more than one suppository is used by the intravaginal method. In the presence of any fungal disease, no more than one candle should be used once.
Overdose of this drug in the form of vaginal suppositories is not possible. But in the event that for some reason it does happen, then poisoning will occur, which will manifest itself as nausea, vomiting, abdominal pain, diarrhea, itching, and in addition, a metallic taste in the mouth. In case of an overdose, ataxia, convulsions or a decrease in leukocytes cannot be ruled out.
Instructions for use
This drug in the form of vaginal suppositories for certain sexual infections is usually used in different ways. For example, with trichomoniasis, vulvovaginal candidiasis or thrush, one suppository is used intravaginally in the evening for ten days.
Medication expiry date
The presented vaginal suppositories should be stored at a temperature not exceeding thirty degrees. The effect of moisture, as well as sunlight, on thismeans should be minimal. The described medicinal product can be stored for no more than five years from the date of release.
Special Instructions
Do not drink alcohol while taking this drug. Even during the next few days after the completion of the therapeutic course, it is recommended not to drink alcoholic beverages. These vaginal suppositories are forbidden to be used for longer than ten days and no more than three times a year. Women who are on peritoneal hemodialysis do not need to adjust the dosage of vaginal suppositories.
It is required to cancel the use of this drug if there is excessive sensitivity of the genital mucosa, and in addition, against the background of the development of leukopenia. During treatment with Klion-D vaginal suppositories, it is forbidden to perform the Nelson test, as it will be false positive. Diabetics and patients with impaired microcirculation should be especially careful with this drug in the form of suppositories.
Medicine cost
Vaginal suppositories "Klion-D 100" in the amount of ten pieces in one package cost an average of two hundred and ten rubles. The described drug is available only by prescription.
Analogues of "Kliona-D 100"
The absolute analogues of this drug are "Neo-Pentoran" along with "Metromicon-Neo". Among the substitutes with a similar action include "Geynomax" along with "Clomegel", "Vagisept", "Ginalin" and "Vagiferon".
Reviews from women
Ohcandles "Klion-D 100" there are mostly satisfied reviews. Women especially praise this drug for its help in the fight against thrush. It is reported that with bacterial diseases of the female genital organs, this drug very quickly and effectively copes with itching and burning.
In addition, women in reviews of "Klion-D 100" write that with bacterial diseases, three days after the use of this medication, the discharge stops. But, unfortunately, there are many complaints about various adverse reactions, such as headache, insomnia and dizziness.
Thus, the presented medical preparation, according to the patients, very quickly removes the most unpleasant medical symptoms. Women find this remedy effective and appropriate for the treatment of various bacterial infections.
