Afobazol is a modern Russian-made over-the-counter drug that can fight anxiety disorders in adults. "Afobazol" acts as a mild tranquilizer and is widely used in general medical practice. The drug has proven itself due to its good tolerability and effectiveness.
Description of the drug "Afobazol"
Synthetic drug related to anxiolytics. "Afobazole" acts as an anti-anxiety agent, without interacting with benzodiazepine receptors, without giving a sedative effect. The drug activates the nervous system, removing asthenia, fatigue and anxiety. Does not relax muscles, does not dull attention, does not impair memory. The drug does not develop dependence and withdrawal syndrome upon discontinuation. Having a sedative effect, "Afobazol" indirectly improves sleep, speeding up the process of falling asleep. Corrects vegetative symptoms and dropsmood.
Absorption and excretion
The drug is taken orally and reaches its maximum concentration, being absorbed from the stomach in less than an hour. The transformation of the active substance takes place in the liver. It is excreted quickly, remaining in the blood for a maximum of two and a half hours. The drug tends to increase its concentration in organs with the most developed blood supply, including the brain, quickly moving into the smallest vessels and capillaries. Excretion is carried out with urine and feces in the form of metabolically modified compounds.
How long does Afobazole work? For a positive anti-anxiety effect, the drug must accumulate within a week, and the maximum benefit is achieved only after four weeks of regular use of the drug.
From what tablets "Afobazol"
The drug is used in the treatment and correction of the following conditions in adults:
- Used for generalized anxiety disorders, accompanied by persistent underlying anxiety, which can occur on the slightest reasons and without them.
- The use of the drug makes sense in agoraphobia, when patients cannot leave the house and be in public places without fear and somatic symptoms.
- Afobazol is prescribed for panic attacks that haunt a person in the form of anxiety attacks with fear of death and autonomic reactions that occur for no apparent reason.
- With neurasthenia has a good effectdue to its light activating action.
- Afobazol acts as an anxiolytic and mood stabilizer in adaptation disorders.
- With somatoform autonomic dysfunction, manifested by various bodily manifestations without damage to organs or body systems.
- In the complex treatment of psychosomatosis (bronchial asthma, hypertension, peptic ulcer, atopic dermatitis, rheumatoid arthritis, hyperthyroidism), "Afobazole" acts as a remedy that positively affects the nervous system by calming. Thus, it stabilizes the condition of the affected organs.
- To supplement the treatment of insomnia that accompanies neurotic disorders, as well as occurring independently.
- Gynecologists use the drug to relieve symptoms in the premenstrual period, as well as to reduce pathological menopausal manifestations (irritability, headaches, sweating, anxiety, mood swings).
- Narcologists and toxicologists prescribe a drug to alleviate the withdrawal syndrome when refusing alcohol after prolonged systematic use, as well as to improve the state of craving for smoking when trying to quit addiction.
- Medicine is widely used by doctors of all profiles to stabilize the state of the nervous system in chronically ill patients, including those with cancer, heart disease and skin manifestations.
How to use
Knowing why Afobazol tablets are prescribed in general medical practice, you need to figure out the dosing regimen and duration of use of this remedy.
The drug is prescribed only for adults after eating orally. The medicine is taken one tablet three times a day with an average daily dose of 30 mg. Under the supervision of a doctor, it is possible to increase the dosage to 60 mg per day. Most often this occurs in a regimen of two tablets three times a day.
The average course of "Afobazol" is from two to four weeks. For long-term treatment of nervous system disorders, this drug may be taken longer, up to three months.
When prescribing and taking medication, it should be remembered that it tends to accumulate in the body for at least a week, and the anti-anxiety effect is fully developed by the end of the month of admission, remaining in the body even after stopping the use of the drug for about two weeks.
Contraindications
Afobazol sedative tablets should not be taken when:
- Pregnancy.
- Breastfeeding the baby.
- In children under 18.
- Individual hypersensitivity reactions to the main or auxiliary components of the drug, including lactose intolerance.
Side effects and overdose
Drugvery well tolerated.
Of the undesirable effects, one can note the occurrence of allergic manifestations in the form of skin rashes, itching of the skin, Quincke's edema. Very rarely, patients are worried about the headache associated with taking the drug "Afobazol".
Taking medication in dosages that are significantly higher than the average recommended may cause overdose symptoms. They manifest themselves in severe drowsiness without muscle relaxation. To remove this unwanted effect, a 20% solution of caffeine sodium benzoate should be injected subcutaneously one milliliter up to three times.
Special Instructions
The drug is not used in childhood.
Pregnant and lactating women should not use this remedy.
Drivers and workers involved at heights and other hazardous types of work can use "Afobazol" in the recommended dosages, since the drug does not have an effect that can slow down the reaction and reduce the concentration ability of a person.
Interactions with other drugs
Let's consider how the drug manifests itself when taken simultaneously with other drugs:
- "Afobazole" does not react with ethyl alcohol.
- Means for hypnosis "Thiopental" does not reduce its effect when taking "Afobazole".
- When used together with "Carbamazepine" and its analogues, the anticonvulsant effect increases.
- Anxiolytic "Diazepam" begins to act with greateffect.
Reviews
When studying the drug "Afobazole" with instructions for use and price, reviews of this drug from doctors and patients also deserve attention.
Psychiatrists, psychotherapists and narcologists note the drug in most cases on the positive side due to the stable anti-anxiety effect and good tolerance. In this case, there is a rule that says not to harm the patient. Therefore, doctors clearly distinguish between the conditions in which it is advisable to prescribe this drug, and in which it will no longer be effective and precious time will be lost.
When doctors prescribe "Afobazole" for neurotic disorders, the degree of disruption of the nervous system, the duration of the disease and what medications the patient took before, what helped and what worsened the state of he alth, are taken into account. It should be remembered that by self-medicating in cases of pathology affecting the brain and peripheral nervous system, you can seriously harm yourself, so all medicinal substances should be prescribed only by a specialist.
Patients who took "Afobazole" in medium therapeutic dosages, doing it regularly, without missing a dose and for the period prescribed by the doctor, characterize this medication as an effective remedy for combating anxiety as the main manifestation of neurosis. Having studied the statistics on sites with drug reviews, one can imaginethe result in the form of a percentage of positive responses, which, according to various sources, ranges from 74 to 100%.
Release form, storage, dispensing of the drug and price in pharmacies
The drug is compressed into white 10mg tablets with added potato starch, cellulose, lactose, magnesium stearate and povidone.
Pills are packaged in blisters of 20 units, which are packed in a cardboard box of three.
Keep the medicine where children can't get it. The storage temperature should not exceed 25 degrees, avoiding direct sunlight and high humidity. The shelf life of the drug is three years from the date of manufacture, it is prohibited to use the product after this period.
The drug can be bought at the pharmacy network without a prescription. Instructions for use are included with each package.
In reviews of "Afobazole" the price of this drug is characterized as acceptable. The cost in pharmacies varies from 326 to 535 rubles.
