In the instructions for use, the tablets "Baclosan" are designated as a centrally acting muscle relaxant. They reduce the excitability of the terminal sections of sensitive afferent fibers and suppress intermediate neurons, thereby inhibiting poly- and monosynaptic transmission of nerve impulses. In addition, the product relieves the pre-stress of the muscle spindles.
The main component of the "Baklosan" composition is baclofen. The drug has a high absorption rate. Its maximum concentration in the blood is reached 2-3 hours after taking the pill. The drug is quickly absorbed by the digestive system. Excreted from the body by the kidneys. The medicine reduces convulsions, lowers the tone of skeletal muscles, as a result of which the sensitivity of the limbs also decreases.
Description and storage
Tablets "Baklosan" have a round biconvex shape, white. They are released in two dosages: 10 mg (there is a divisive risk), 25 mg. They are packed in polypropylene jars of 50 pieces, which are packed in a cardboard box. They release the drug without a doctor's prescription.
The shelf life of the medicine is 5 years. It must be stored in a dry and dark placetemperature not lower than +25 °C, away from children.
Indications
Baklosan tablets have the following indications for use:
- cerebral palsy;
- multiple sclerosis;
- traumatic brain injury;
- diseases of the spinal cord of traumatic, degenerative and infectious origin;
- alcoholism;
- stroke;
- disorders of the nervous system;
- meningitis.
Often, experts prescribe medication for various injuries, fractures, dislocations and pathologies of the spinal cord. Alcohol and Baklosan (this is indicated in the instructions for use) are incompatible.
The drug should be taken with meals. The tablet is washed down with water. Begin treatment with 5 mg three times a day, the dose is increased every three days. The amount of the drug is increased until the patient shows a significant improvement. The dosage is increased only by a doctor, in some exceptional cases it can reach 25 mg. Cancellation of "Baklosan" must be agreed with the attending physician. The maximum daily dose is 100 mg.
Side results
Side effects of Baklosan are rarely recorded. With great care, the medication should be taken by older people who are susceptible to the components of the remedy. Possible side effects:
- nausea and vomiting;
- constipation and diarrhea;
- weakness and dizziness;
- puffiness;
- urinary incontinence;
- depressive state;
- drowsy;
- numbness;
- dry mouth.
The drug is produced in the form of small biconvex tablets. The main component of the drug is, as already mentioned, baclofen. Instructions for use for "Baclosan" indicates that the additional components are: potato starch, talc, magnesium stearate, gelatin and lactose.
Overdose
Overdose of the drug manifests itself with the following symptoms:
- severe muscle hypotension;
- respiratory depression;
- confusion;
- coma (in cases where consciousness returns, muscle hypotension can be observed up to 72 hours).
According to the instructions for use for Baklosan, in case of poisoning with the drug and the appearance of the above symptoms, diuretics should be immediately given to the patient, drinking plenty of water is recommended. If oppressed breathing is observed, then a procedure for artificial lung ventilation is prescribed.
Special Instructions
If Baclosan is prescribed to a patient with diabetes mellitus or liver diseases, then periodically it is necessary to monitor the activity of special enzymes - liver transaminases, as well as blood glucose and alkaline phosphatase.
According to the instructions for the drug, for the duration of treatment, everyone who takes it should refrain from performing hazardous activities that require a quick mental and motor reaction, increased attention.
Key aspects of addiction
Cure is not addictive in a physics project. Chemically, the agent is not dangerous, howeverBaclofen as a functioning substance can activate the psychological need for continued use of the pills.
It is known that Baklosan is able to constantly increase the euphoric result from other drugs, for this reason, experienced drug addicts use this medication to enhance the effect of narcotic substances. In some cases, they try to combine a muscle relaxant with alcohol, which is deadly.
Tolperison
The main active substance is tolperisone hydrochloride. Auxiliary components - citric acid, lactose acid (milk sugar), hyprolose, crospovidone, stearic carbonic acid.
Pharmacological action
"Tolperizon" - an analogue of "Baklosan", belongs to the group of N-cholinolytics. A muscle relaxant drug that has a selective effect (depressant) on the caudal part of the reticular formation of the brain, has anticholinergic central properties. It does not have any effect on the peripheral parts of the human nervous system. The drug is characterized by a weak vasodilating and antispasmodic effect.
Indications for use
The drug is prescribed in the following cases:
- Diseases with stiffness, muscle spasm and dystonia, obliterating diseases of the arteries (thromboangiitis obliterans and atherosclerosis of the vessels of the upper and lower extremities, diabetic angiopathy, Raynaud's syndrome).
- Cerebral and spinal palsy (contracturelimbs, muscle spasm and hypertonicity, spinal automatism).
- Motor disorders resulting from damage to the subcortical-thalamic connections and basal ganglia.
- Little's disease, disorders of post-thrombotic venous and lymphatic circulation, trophic ulcers of the lower leg, epilepsy, hypertonicity, combined with a violation of muscle tone of a different type, as well as encephalopathy, which has a vascular etiology.
Dosage, contraindications and overdose
The drug is taken orally (regardless of food intake) with water. The initial dosage for adults is 50 mg two or three times a day. Gradually increase it, bringing up to 150 mg. The duration of the course is determined by the doctor, it depends on the nature of the course of the disease and its severity.
The drug should not be taken in the following cases: myasthenia gravis, age under 1 year, hypersensitivity, and during pregnancy and lactation.
Overdose of a non-biological element (tolperisone) can provoke nervousness in a patient (especially in a child), respiratory paralysis, convulsions (tonic and cyclic), ataxia.
Theizalud
Indications for the use of "Tizalud" analogue of "Baklosan":
- painful muscle contractions due to damage to the spine, as well as surgical intervention (postoperative period);
- skeletal muscle spasm in neurological diseases: disseminatedsclerosis, myelopathy, degenerative diseases of the spinal cord, stroke).
Contraindication: sensitivity to the active substance - tizanidine. With caution, the drug is prescribed for violations of the function of the kidneys and liver. "Tizalud" should not be used during pregnancy, except in situations where the predicted benefit to the mother outweighs the likely threat to the fetus. If you need to use the substance during lactation, you must stop breastfeeding.
Mydocalm
"Mydocalm" is a muscle relaxant of central action. Instructions for use for Baklosan and Mydocalm are very similar. The latter is prescribed under the following conditions:
- muscle hypertonicity;
- accompanied by muscular dystonia (including in childhood) encephalopathy;
- muscle spasm;
- CP;
- neurological organic and degenerative diseases in which striated muscle tone is observed.
The main effect of Mydocalm is to relax muscles and solve the problem of muscle spasms caused by various factors. The effectiveness of the drug has been clinically proven in blind studies. The action of "Mydocalm" is central, due to which the effect is carried out directly on the brain, The drug has contraindications:
- individual intolerance;
- epilepsy;
- psychosis;
- Parkinson's disease.
The use of the drug during pregnancy is allowed in exceptional cases, when the effectiveness of therapy is higher than the risk to the child.
"Mydocalm" is taken orally, the tablet should be swallowed with water. At the beginning of the dose for an adult - 50 mg two or three times a day, followed by a three-fold increase in dose. If side effects occur (muscle weakness, low blood pressure, headache), the dose of the drug should be reduced.
Other properties
Other useful properties of the drug: reducing the high excitability of the spinal cord, stabilizing the sheaths of receptive and motor fibers, reducing stiffness and muscle tone. Unlike other similar pharmaceuticals, "Mydocalm" does not show a sedative effect, does not have an excessively negative effect on the hematopoietic system.
Other analogues
In the pharmacy you can find a large number of analogues, such as:
- "Katadolon";
- "Memikar";
- "Memorel";
- "Mementine".
Katadolon should be taken with great care. This drug is strong enough, but it is not considered a narcotic. It has a strong analgesic effect. "Baclofen" also helps to get rid of pain, relieve muscle tension. With the help of Memorel tablets, you can restore a normal mental state, improve memory. "Memantine"available as a powder, it helps increase stamina.
